Compounds > atropine

Page last updated: 2024-09-05

atropine and medetomidine

atropine has been researched along with medetomidine in 19 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (medetomidine)	Trials (medetomidine)	Recent Studies (post-2010) (medetomidine)
26,711	1,259	1,697	1,335	296	444

Protein Interaction Comparison

Protein	Taxonomy	atropine (IC50)	medetomidine (IC50)
Alpha-2A adrenergic receptor	Homo sapiens (human)		3.4

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (10.53)	18.7374
1990's	8 (42.11)	18.2507
2000's	8 (42.11)	29.6817
2010's	1 (5.26)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Short, CE	1
Räihä, JE; Räihä, MP; Short, CE	1
Palmu, L; Vainio, O	1
Benson, GJ; Ko, JC; Olson, WA; Thurmon, JC; Tranquilli, WJ; Vaha-Vahe, AT	1
Ishiguro, T; Nishimura, R; Sakaguchi, M; Sasaki, N; Takeuchi, A; Tamura, H	1
Benson, GJ; Ko, JC; Olson, WA; Thurmon, JC; Tranquilli, WJ	1
Bufalari, A; Giannoni, C; Short, CE; Vainio, O	1
Alibhai, HI; Clarke, KW; Lee, YH; Thompson, J	1
Mohammad, FK; Yakoub, LK	1
Benson, GJ; Grimm, KA; Olson, WA; Thurmon, JC; Tranquilli, WJ	1
Fox, SM; Ko, JC; Mandsager, RE	1
Emons, VM; Ince, C; Zuurbier, CJ	1
O'Flaherty, K; Ugarte, CE	1
Barthez, PY; Pollak, YW; Schaafsma, IA	1
Blyde, D; Johnston, S; Lemon, J; Ward, DG	1
Halbertsma, FJ; Heunks, LM; Santosa, JP; Scheffer, GJ; Snijdelaar, DG; VAN DE Pol, FM; VAN DEN Brink, IA; VAN DER Hoeven, JG; VAN Egmond, J; Vaneker, M	1
Rózańska, D	1
Benson, GJ; Greene, SA; Grimm, KA; Thurmon, JC; Tranquilli, WJ	1

Trials

6 trial(s) available for atropine and medetomidine

Article	Year
Hemodynamic and anesthetic effects of etomidate infusion in medetomidine-premedicated dogs. American journal of veterinary research, 1994, Volume: 55, Issue:6 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Atropine; Dogs; Drug Combinations; Etomidate; Female; Hemodynamics; Imidazoles; Infusions, Intravenous; Male; Medetomidine; Premedication; Respiration; Safety	1994
Effects of preemptive atropine administration on incidence of medetomidine-induced bradycardia in dogs. Journal of the American Veterinary Medical Association, 2001, Jan-01, Volume: 218, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Bradycardia; Cross-Over Studies; Cyanosis; Dog Diseases; Dogs; Female; Heart Rate; Linear Models; Medetomidine; Muscarinic Antagonists; Tongue	2001
The use of a medetomidine, butorphanol and atropine combination to enable blood sampling in young pigs. New Zealand veterinary journal, 2005, Volume: 53, Issue:4 Topics: Anesthesia; Anesthetics, Combined; Animals; Animals, Newborn; Atropine; Blood Specimen Collection; Butorphanol; Injections, Intramuscular; Male; Medetomidine; Swine	2005
Effect of four sedative and anesthetic protocols on quantitative thyroid scintigraphy in euthyroid cats. American journal of veterinary research, 2006, Volume: 67, Issue:8 Topics: Anesthetics; Animals; Atropine; Cats; Female; Hypnotics and Sedatives; Ketamine; Male; Medetomidine; Midazolam; Propofol; Radionuclide Imaging; Radiopharmaceuticals; Salivary Glands; Sodium Pertechnetate Tc 99m; Thyroid Gland	2006
Evaluation of medetomidine-midazolam-atropine (MeMiA) anesthesia maintained with propofol infusion in New Zealand White rabbits. Polish journal of veterinary sciences, 2009, Volume: 12, Issue:2 Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Intravenous; Animals; Atropine; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Male; Medetomidine; Midazolam; Propofol; Rabbits	2009
Anesthetic and cardiopulmonary effects of propofol in dogs premedicated with atropine, butorphanol, and medetomidine. Veterinary therapeutics : research in applied veterinary medicine, 2001,Winter, Volume: 2, Issue:1 Topics: Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Animals; Atropine; Blood Pressure; Butorphanol; Dogs; Female; Male; Medetomidine; Propofol; Time Factors	2001

Other Studies

13 other study(ies) available for atropine and medetomidine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effects of anticholinergic treatment on the cardiac and respiratory systems in dogs sedated with medetomidine. The Veterinary record, 1991, Oct-05, Volume: 129, Issue:14 Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Atropine; Bradycardia; Dog Diseases; Dogs; Electrocardiography; Female; Glycopyrrolate; Heart Block; Heart Rate; Imidazoles; Medetomidine; Respiration	1991
Medetomidine as a preanesthetic prior to ketamine-HCL and halothane anesthesia in laboratory beagles. Acta veterinaria Scandinavica. Supplementum, 1989, Volume: 85 Topics: Adrenergic alpha-Agonists; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Halothane; Imidazoles; Injections, Intravenous; Ketamine; Medetomidine; Preanesthetic Medication	1989
Cardiovascular and respiratory effects of medetomidine in dogs and influence of anticholinergics. Acta veterinaria Scandinavica, 1989, Volume: 30, Issue:4 Topics: Animals; Atropine; Blood Pressure; Dogs; Female; Glycopyrrolate; Heart Rate; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Pyrrolidines; Respiration	1989
Cardiopulmonary effects of a combination of medetomidine and butorphanol in atropinized pigs. The Journal of veterinary medical science, 1993, Volume: 55, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Butorphanol; Castration; Drug Interactions; Heart; Heart Rate; Hypnotics and Sedatives; Imidazoles; Lung; Medetomidine; Pulmonary Circulation; Respiratory Function Tests; Swine; Vascular Resistance	1993
Hemodynamic and analgesic effects of propofol infusion in medetomidine-premedicated dogs. American journal of veterinary research, 1994, Volume: 55, Issue:3 Topics: Analgesics; Animals; Atropine; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Dogs; Female; Heart Rate; Hemodynamics; Imidazoles; Infusions, Intravenous; Injections, Intravenous; Male; Medetomidine; Oxygen; Partial Pressure; Premedication; Propofol; Pulmonary Artery; Pulmonary Circulation; Respiration	1994
Comparative responses to propofol anaesthesia alone and with alpha 2-adrenergic medications in a canine model. Acta veterinaria Scandinavica, 1996, Volume: 37, Issue:2 Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Anesthetics, Intravenous; Animals; Atropine; Blood Pressure; Dogs; Drug Interactions; Female; Imidazoles; Male; Medetomidine; Preanesthetic Medication; Propofol; Respiration; Time Factors	1996
Cardiopulmonary effects of combinations of medetomidine hydrochloride and atropine sulphate in dogs. The Veterinary record, 1996, Jan-06, Volume: 138, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Atropine; Bradycardia; Dog Diseases; Dogs; Drug Combinations; Drug Interactions; Heart; Heart Rate; Hypertension; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Respiratory Physiological Phenomena; Respiratory System	1996
Medetomidine protection against diazinon-induced toxicosis in mice. Toxicology letters, 1997, Sep-19, Volume: 93, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazinon; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Imidazoles; Insecticides; Lethal Dose 50; Male; Medetomidine; Mice; Nervous System Diseases; Parasympatholytics; Survival Rate	1997
The pharmacodynamics of thiopental, medetomidine, butorphanol and atropine in beagle dogs. Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:2 Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Arousal; Atropine; Blood Pressure; Butorphanol; Dogs; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Medetomidine; Thiopental	1998
Hemodynamics of anesthetized ventilated mouse models: aspects of anesthetics, fluid support, and strain. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6 Topics: Anesthesia; Anesthetics; Animals; Atropine; Blood Pressure; Butyrophenones; Fentanyl; Fluid Therapy; Heart Rate; Hemodynamics; Isoflurane; Ketamine; Medetomidine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Midazolam; Models, Animal; Respiration, Artificial; Species Specificity	2002
Anesthesia of captive African wild dogs (Lycaon pictus) using a medetomidine-ketamine-atropine combination. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2006, Volume: 37, Issue:2 Topics: Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Animals, Wild; Atropine; Blood Chemical Analysis; Blood Gas Analysis; Carnivora; Hypnotics and Sedatives; Injections, Intramuscular; Ketamine; Male; Medetomidine; Time Factors	2006
Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy mice. Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:6 Topics: Anesthetics, Inhalation; Animals; Atropine; Blood Pressure; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Interleukin-1beta; Isoflurane; Ketamine; Leukocyte Count; Lung; Male; Medetomidine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Pneumonia; Respiration, Artificial; Tumor Necrosis Factor-alpha	2009