Page last updated: 2024-09-05

atropine and meclofenamic acid

atropine has been researched along with meclofenamic acid in 16 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(meclofenamic acid)
Trials
(meclofenamic acid)
Recent Studies (post-2010) (meclofenamic acid)
26,7111,2591,6971,0015572

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)meclofenamic acid (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)0.0675
Prostaglandin G/H synthase 1Homo sapiens (human)0.2115
Mitogen-activated protein kinase 1Homo sapiens (human)3.144
Prostaglandin G/H synthase 2Homo sapiens (human)0.1618
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.1
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.5307
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.74
Aldo-keto reductase family 1 member C1Homo sapiens (human)2.3533
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.164
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.1

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's6 (37.50)18.2507
2000's0 (0.00)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
McGrath, MA; Shepherd, JT1
Feng, CJ; Holton, RH; Jahr, JS1
Fitzpatrick, JM; Grant, BJ1
Archer, SL; Chesler, E; Kulik, TJ; Weir, EK1
Hyman, AL; Kadowitz, PJ; Lippton, H; Neely, CF; Neiman, M1
Cornell, RP1
Grunstein, MM; Tanaka, DT1
Hyman, AL; Kadowitz, PJ1
Chen, BB; Clougherty, PW; Geller, HS; Goll, HM; Murray, PA; Nyhan, DP1
Cooke, RG; Nicholson, T1
Kadowitz, PJ; McMahon, TJ1
Ferrara, JJ; Flint, LM; Force, SD; Franklin, EW; Hyman, AL; Lippton, HL; Taheri, PA1
Champion, HC; Del Rio, O; Garrison, EA; Kadowitz, PJ; Santiago, JA; Smith, RE1
Bellan, JA; Holton, RH; Jahr, JS; Kadowitz, PJ; Lian, TS; Nossaman, BD1

Reviews

1 review(s) available for atropine and meclofenamic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for atropine and meclofenamic acid

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Inhibition of adrenergic neurotransmission in canine vascular smooth muscle by histamine: mediation by H2-receptors.
    Circulation research, 1976, Volume: 39, Issue:4

    Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Hindlimb; Histamine; Meclofenamic Acid; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Neural Inhibition; Norepinephrine; Propranolol; Saphenous Vein; Synaptic Transmission; Vasomotor System

1976
Effect of desmopressin acetate on hindlimb perfusion pressure in rats: what is the mechanism?
    Anesthesia and analgesia, 1992, Volume: 75, Issue:3

    Topics: Anesthesia; Animals; Arginine; Atropine; Blood Pressure; Chlorobutanol; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Hindlimb; Male; Meclofenamic Acid; Nitric Oxide; Nitroarginine; Perfusion; Propranolol; Rats; Rats, Inbred Strains; Vascular Resistance

1992
Effects of pulmonary vascular obstruction on right ventricular afterload.
    The American review of respiratory disease, 1990, Volume: 141, Issue:4 Pt 1

    Topics: Animals; Atropine; Biomechanical Phenomena; Compliance; Constriction; Dogs; Ketanserin; Meclofenamic Acid; Models, Cardiovascular; Positive-Pressure Respiration; Pulmonary Artery; Pulmonary Circulation; Pulmonary Embolism; Pulsatile Flow; Vagotomy; Vascular Resistance; Ventricular Function

1990
The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 183, Issue:1

    Topics: Acetylcysteine; Animals; Aorta; Atropine; Blood Pressure; Dinoprost; Dogs; Hypoxia; Lung; Meclofenamic Acid; Methylene Blue; Prostaglandins F; Pulmonary Artery; Substance P; Vascular Resistance; Vasoconstriction

1986
Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Blood Pressure; Cats; Cimetidine; Meclofenamic Acid; Nitroglycerin; Propranolol; Pulmonary Circulation; Vasodilation; Xanthines

1989
Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 2

    Topics: Acetophenones; Adrenocorticotropic Hormone; Animals; Atropine; Autonomic Nervous System; Body Temperature; Cerebral Ventricles; Dinoprostone; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperinsulinism; Ibuprofen; Indomethacin; Injections, Intraventricular; Insulin; Insulin Secretion; Interleukin-1; Male; Meclofenamic Acid; Phentolamine; Propranolol; Propyl Gallate; Rats; Reference Values; SRS-A; Tetrazoles; Vagotomy

1989
Vasoactive effects of substance P on isolated rabbit pulmonary artery.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:4

    Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Isometric Contraction; Meclofenamic Acid; Muscle Relaxation; Neostigmine; Phentolamine; Pulmonary Artery; Rabbits; Serotonin; Substance P; Tetrodotoxin

1985
Influence of tone on responses to acetylcholine in the rabbit pulmonary vascular bed.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Dose-Response Relationship, Drug; Female; Gallamine Triethiodide; Indomethacin; Lung; Male; Meclofenamic Acid; Pirenzepine; Rabbits; Receptors, Muscarinic; Vascular Resistance; Vasodilation

1989
Combined neurohumoral block modulates pulmonary vascular P/Q relationship in conscious dogs.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Body Weight; Captopril; Cardiac Output; Cyclooxygenase Inhibitors; Dogs; Hemodynamics; Indomethacin; Lung; Meclofenamic Acid; Peptidyl-Dipeptidase A; Prazosin; Propranolol; Receptors, Angiotensin; Receptors, Vasopressin; Vasodilation

1988
The reticular groove and drug absorption.
    Journal of veterinary pharmacology and therapeutics, 1981, Volume: 4, Issue:4

    Topics: Animals; Atropine; Female; Intestinal Absorption; Male; Meclofenamic Acid; Pharmaceutical Preparations; Reticulum; Sheep; Time Factors

1981
Analysis of responses to substance P in the pulmonary vascular bed of the cat.
    The American journal of physiology, 1993, Volume: 264, Issue:2 Pt 2

    Topics: Animals; Atropine; Blood Pressure; Cats; Female; Glyburide; Male; Meclofenamic Acid; Pulmonary Circulation; Respiration; Substance P; Vasodilation

1993
Analysis of regional hemodynamic regulation in response to scald injury.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Adamantane; Animals; Arginine; Atropine; Blood Pressure; Burns; Diphenhydramine; Dogs; Femoral Artery; Hemodynamics; Hindlimb; Histamine; Isoproterenol; Meclofenamic Acid; Methoxamine; Methysergide; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroglycerin; Pulmonary Circulation; Ranitidine; Regional Blood Flow; Ritanserin; Serotonin; Serotonin Receptor Agonists; Time Factors; Triazines; Ultrasonography; Vascular Resistance; Vasodilation; Verapamil; Xanthines

1994
Analysis of responses to kallidin, DABK, and DAK in feline hindlimb vascular bed.
    The American journal of physiology, 1995, Volume: 269, Issue:6 Pt 2

    Topics: Adamantane; Animals; Arginine; Atropine; Blood Vessels; Bradykinin; Bradykinin Receptor Antagonists; Cats; Female; Hindlimb; Kallidin; Male; Meclofenamic Acid; Morpholines; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channels

1995
Vasodilator responses to desmopressin and its diluent, chlorobutanol, in the hindquarters vascular bed of the cat.
    Journal of medicine, 1996, Volume: 27, Issue:1-2

    Topics: Animals; Atropine; Cats; Chlorobutanol; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Hindlimb; Hydrogen-Ion Concentration; Meclofenamic Acid; Nitroarginine; Perfusion; Propranolol; Tachyphylaxis; Vascular Resistance; Vasodilator Agents

1996