atropine has been researched along with losartan in 21 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (losartan) | Trials (losartan) | Recent Studies (post-2010) (losartan) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 7,231 | 1,245 | 2,118 |
| Protein | Taxonomy | atropine (IC50) | losartan (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 9.01 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.882 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.019 | |
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.0018 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0247 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0234 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0032 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.047 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.025 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0118 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.019 | |
| Platelet glycoprotein VI | Homo sapiens (human) | 4 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.1481 | |
| Type-1 angiotensin II receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.2884 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Le Mevel, JC; Mabin, D; Pamantung, TF; Vaudry, H | 1 |
| Barnes, JC; Hawcock, AB | 1 |
| Kim, HJ; Kim, KS; Lee, EJ; Lee, JH; Lee, WJ; Park, JS; Yang, EK | 1 |
| Höhle, S; Qadri, F; Rascher, W; Unger, T; Waldmann, T; Wolf, A | 1 |
| Blume, A; Culman, J; Herdegen, T; Lebrun, CJ; Moellenhoff, E; Unger, T | 1 |
| Johnson, AK; Xu, Z | 1 |
| Bishop, VS; LaGrange, LP; Toney, GM | 1 |
| Dendorfer, A; Dominiak, P; Raasch, W; Ziegler, A | 1 |
| Anyukhovsky, EP; Danilo, P; Hefer, D; Janse, MJ; Rosen, MR; Rosen, TS; Sosunov, EA | 1 |
| Edebo, A; Ewert, S; Fändriks, L; Johnsson, E; Olbers, T; Spak, E | 1 |
| Arora, R; Prabhakar, H; Rath, GP | 1 |
| Asnar, DS; Colombari, DS; De Luca, LA; de Paula, PM; Menani, JV; Roncari, CF | 1 |
| Colombari, DS; Colombari, E; David, RB; De Luca, LA; De Paula, PM; Johnson, AK; Johnson, RF; Menani, JV; Roncari, CF | 1 |
| de Araújo, JE; de Paula Facioli, T; de Souza, HC; Gastaldi, AC; Maida, KD | 1 |
| Gatineau, E; Gong, MC; Yiannikouris, F | 1 |
1 review(s) available for atropine and losartan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
20 other study(ies) available for atropine and losartan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Intracerebroventricular administration of angiotensin II increases heart rate in the conscious trout.
Topics: Angiotensin II; Animals; Atropine; Biphenyl Compounds; Blood Pressure; Cerebral Ventricles; Consciousness; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Injections, Intra-Arterial; Injections, Intraventricular; Losartan; Tetrazoles; Trout | 1994 |
Pharmacological characterization of the contractile responses to angiotensin analogues in guinea-pig isolated longitudinal muscle of small intestine.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Tetrazoles; Tetrodotoxin | 1993 |
Effect of brain angiotensin II AT1, AT2, and cholinergic receptor antagonism on drinking in water-deprived rats.
Topics: Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Cholinergic Antagonists; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cholinergic; Receptors, Neurotransmitter; Recombinant Proteins; Tetrazoles; Thirst; Time Factors; Water Deprivation | 1996 |
Differential contribution of angiotensinergic and cholinergic receptors in the hypothalamic paraventricular nucleus to osmotically induced AVP release.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arginine Vasopressin; Atropine; Blood Pressure; Hexamethonium; Losartan; Male; Muscarinic Antagonists; Nicotinic Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Cholinergic; Saline Solution, Hypertonic | 1998 |
Central angiotensin AT1 and muscarinic receptors in ITF expression on intracerebroventricular NaCl.
Topics: Animals; Atropine; Cerebral Ventricles; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Hypothalamus; Immediate-Early Proteins; Injections, Intraventricular; Losartan; Male; Neurons; Organ Specificity; Oxytocin; Paraventricular Hypothalamic Nucleus; Preoptic Area; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Muscarinic; Saline Solution, Hypertonic; Supraoptic Nucleus; Transcription Factors; Vasopressins; Zinc Fingers | 1998 |
Non-NMDA receptor antagonist-induced drinking in rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Cerebral Ventricles; Dizocilpine Maleate; Drinking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Losartan; Male; Quinoxalines; Rats; Rats, Sprague-Dawley | 1998 |
Chronic angiotensin II infusion attenuates the renal sympathoinhibitory response to acute volume expansion.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Chlorisondamine; Ganglionic Blockers; Heart Rate; Hematocrit; Kidney; Losartan; Male; Parasympatholytics; Plasma Volume; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2003 |
Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation.
Topics: Adrenergic alpha-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desipramine; Diastole; Dose-Response Relationship, Drug; Losartan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reserpine; Sympathectomy, Chemical; Sympathetic Nervous System; Symporters; Tetrazoles; Tubocurarine; Yohimbine | 2004 |
Region-specific, pacing-induced changes in repolarization in rabbit atrium: an example of sensitivity to the rare.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Apamin; Atrial Fibrillation; Atropine; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiac Pacing, Artificial; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Atria; Heart Conduction System; Losartan; Nifedipine; Potassium Channel Blockers; Propranolol; Pulmonary Veins; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Muscarinic; Ryanodine | 2005 |
Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro.
Topics: Adrenergic Antagonists; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atropine; Blotting, Western; Cholinergic Antagonists; Dose-Response Relationship, Drug; Female; Guanethidine; Humans; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Species Specificity | 2006 |
Sudden cardiac standstill during skin flap elevation in a patient undergoing craniotomy.
Topics: Aged; Amlodipine; Anesthesia, General; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Brain Neoplasms; Calcium Channel Blockers; Craniotomy; Dermatologic Surgical Procedures; Female; Heart Arrest; Heart Rate; Humans; Hypertension; Losartan; Reflex, Abnormal; Skin; Surgical Flaps; Trigeminal Nerve | 2007 |
Involvement of central cholinergic mechanisms on sodium intake induced by gabaergic activation of the lateral parabrachial nucleus.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atropine; Captopril; Diuretics; Drinking; Eating; Furosemide; GABA Agonists; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic; Sodium Chloride | 2013 |
Angiotensinergic and cholinergic receptors of the subfornical organ mediate sodium intake induced by GABAergic activation of the lateral parabrachial nucleus.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Cells, Cultured; Drinking Behavior; GABA-A Receptor Agonists; Losartan; Male; Muscarinic Antagonists; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Receptors, Cholinergic; Receptors, GABA; Receptors, Neurotransmitter; Sodium Chloride; Subfornical Organ; Water | 2014 |
Physical training associated with Enalapril but not to Losartan, results in better cardiovascular autonomic effects.
Topics: Animals; Antihypertensive Agents; Atropine; Autonomic Nervous System; Baroreflex; Blood Pressure; Combined Modality Therapy; Disease Models, Animal; Enalapril; Exercise Therapy; Heart Rate; Hypertension; Losartan; Male; Parasympatholytics; Propranolol; Rats, Inbred SHR; Sedentary Behavior; Swimming | 2017 |
Soluble Prorenin Receptor Increases Blood Pressure in High Fat-Fed Male Mice.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Baroreflex; Blood Pressure; Chlorisondamine; Diet, High-Fat; Ganglionic Blockers; Infusions, Subcutaneous; Leptin; Losartan; Male; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Propranolol; Prorenin Receptor; Receptors, Cell Surface | 2019 |