Page last updated: 2024-09-05

atropine and levorphanol

atropine has been researched along with levorphanol in 13 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(levorphanol)
Trials
(levorphanol)
Recent Studies (post-2010) (levorphanol)
26,7111,2591,6976342618

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)levorphanol (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)8
Glutamate receptor ionotropic, NMDA 2DHomo sapiens (human)2.6
Glutamate receptor ionotropic, NMDA 3BHomo sapiens (human)2.6
Mu-type opioid receptorHomo sapiens (human)0.0001
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)4.45
Delta-type opioid receptorHomo sapiens (human)0.004
Kappa-type opioid receptorHomo sapiens (human)0.004
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0006
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)4.45
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)4.45
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)4.45
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)2.6
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)2.6
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)2.6
Glutamate receptor ionotropic, NMDA 2CHomo sapiens (human)2.6
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)4.45
Glutamate receptor ionotropic, NMDA 3AHomo sapiens (human)2.6
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)4.45
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)4.45

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bayerl, H; Zieglgänsberger, W1
Lajtha, A; Wajda, IJ1
Michaelson, DM; Oron, L; Sarne, Y1
Beamer, KC; Daly, T; Head, R; Vargish, T1
Askew, WE; Charalampous, KD1
Brister, CC; Davis, WM1
Goldstein, A1
Carmichael, FJ; Israel, Y1
Dundee, JW; McDowell, SA1
Smits, SE; Takemori, AE1
JACOBSEN, FG; SCHAFII-LASCHTENESCHAI, AH; ZETLER, G1

Reviews

2 review(s) available for atropine and levorphanol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Interactions of narcotic antagonists with receptor sites.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Acetylcholine; Animals; Atropine; Binding Sites; Brain; Chromatography; Drug Tolerance; Electric Stimulation; Haplorhini; Humans; Kinetics; Levorphanol; Methadone; Mice; Molecular Conformation; Morphine; Naloxone; Narcotic Antagonists; Rats; Receptors, Drug; Structure-Activity Relationship; Substance Withdrawal Syndrome; Time Factors

1973

Other Studies

11 other study(ies) available for atropine and levorphanol

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
The mechanism of inhibition of neuronal activity by opiates in the spinal cord of cat.
    Brain research, 1976, Oct-08, Volume: 115, Issue:1

    Topics: Acetylcholine; Action Potentials; Animals; Atropine; Calcium; Cats; Depression, Chemical; Dextrorphan; Dose-Response Relationship, Drug; Evoked Potentials; Female; Glutamates; Glycine; Levorphanol; Male; Membrane Potentials; Morphine; Naloxone; Neurons; Procaine; Spinal Cord; Synapses

1976
Corpus striatum as the site of drug action.
    Voprosy biokhimii mozga, 1975, Volume: 10

    Topics: Acetylcholine; Animals; Atropine; Corpus Striatum; Dextrorphan; Dopamine; Female; Levorphanol; Morphine; Naloxone; Norepinephrine; Opium; Physostigmine; Rats; Serotonin

1975
Nonopioid effect of morphine on electrically evoked acetylcholine release from Torpedo electromotor neurons.
    Journal of neurochemistry, 1992, Volume: 58, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Echothiophate Iodide; Electric Organ; Electric Stimulation; Levorphanol; Ligands; Morphine; Narcotics; Neurons; Stereoisomerism; Torpedo; Tubocurarine

1992
Myocardial opiate receptor activity is stereospecific, independent of muscarinic receptor antagonism, and may play a role in depressing cardiac function.
    Surgery, 1987, Volume: 102, Issue:2

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cardiac Output; Dextrorphan; Drug Interactions; Heart; Heart Rate; Levorphanol; Morphine; Muscarinic Antagonists; Myocardium; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism

1987
Effect of non-opiate antagonists on stereospecific opiate receptor binding of tritiated naloxone.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Atropine; Binding, Competitive; Brain; Bucladesine; Filtration; Fluorides; Isoproterenol; Levorphanol; Male; Mice; Naloxone; Phenoxybenzamine; Pimozide; Propranolol; Receptors, Drug; Structure-Activity Relationship; Theophylline; Tritium

1974
Antagonism of acute lethality of narcotic analgesics in aggregated and isolated mice by the central cholinomimetic action of pilocarpine.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 210, Issue:2

    Topics: Analgesics, Opioid; Animals; Atropine; Atropine Derivatives; Crowding; Depression, Chemical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Levorphanol; Male; Meperidine; Methadone; Mice; Morphine; Motor Activity; Parasympathomimetics; Pentazocine; Pilocarpine; Social Isolation; Stimulation, Chemical; Time Factors

1974
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2

    Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium

1973
Neurolept anaesthesia: a comparison with a conventional technique for major surgery.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:5

    Topics: Anesthesia, Inhalation; Atropine; Benperidol; Blood Pressure; Electrocardiography; Fentanyl; Humans; Intubation, Intratracheal; Levorphanol; Meperidine; Methods; Neuroleptanalgesia; Nitrous Oxide; Oxygen; Postoperative Complications; Preanesthetic Medication; Pulse; Surgical Procedures, Operative; Thiopental; Time Factors; Tubocurarine

1971
Studies on the receptors involved in the action of the various agents in the phenylbenzoquinone analgesic assay in mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:3

    Topics: Analgesics; Animals; Aspirin; Atropine; Cyclazocine; Drug Tolerance; Levorphanol; Male; Methadone; Mice; Morphine; Nalorphine; Pentazocine; Physostigmine; Quinones; Receptors, Drug; Spasm

1970
[THE INHIBITION OF MORPHINE, LEVORPHAN, METHADONE AND PETHIDINE ANALGESIA IN MICE BY "SPECIFIC" AND "NONSPECIFIC" ANTAGONISTS].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1963, Nov-08, Volume: 246

    Topics: Analgesia; Animals; Atropine; Levorphanol; Meperidine; Mephenesin; Meprobamate; Methadone; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain Management; Peptides; Phenobarbital; Research; Reserpine; Tissue Extracts

1963