Compounds > atropine
Page last updated: 2024-09-05

atropine and leukotriene d4

atropine has been researched along with leukotriene d4 in 9 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(leukotriene d4)		Trials
(leukotriene d4)		Recent Studies (post-2010) (leukotriene d4)
26,7111,2591,6976974297

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)leukotriene d4 (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.0007
Canalicular multispecific organic anion transporter 1Rattus norvegicus (Norway rat)5.48
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.0007
Cysteinyl leukotriene receptor 1Homo sapiens (human)0.0039

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (66.67)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Barrett, KE; Bidinger, J; Cooke, HJ; Javed, NH; Wang, YZ1
Furuhama, K; Matsumoto, K; Takami, M; Takata, Y; Tsukada, W1
Becker, K; Dobreva, G; Frieling, T; Häussinger, D; Rupprecht, C; Schemann, M1
Amemiya, T; Fujimura, M; Ishiura, Y; Matsuda, T; Myou, S; Sasaki, S1
Kokubun, S; Yamashita, T1
Berglund, M; Dalence-Guzmán, MF; Jönsson, P; Persson, CG; Skogvall, S; Sterner, O; Svensson, K1
Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M1

Reviews

1 review(s) available for atropine and leukotriene d4

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993

Other Studies

8 other study(ies) available for atropine and leukotriene d4

ArticleYear
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Enhanced tissue responsiveness in colonic ion transport of cow's milk-sensitized guinea pigs.
    Agents and actions, 1994, Volume: 41, Issue:1-2

    Topics: Animals; Atropine; Bumetanide; Cattle; Cells, Cultured; Chlorides; Colon; Dicarboxylic Acids; Electric Stimulation; Guinea Pigs; Histamine Release; Immunization; Intestinal Mucosa; Ion Transport; Lactoglobulins; Leukotriene D4; Male; Mast Cells; Milk; Piroxicam; Tetrodotoxin

1994
Possible role of thromboxane A2 in hyperresponsiveness of isolated rat lung tissue in a Sephadex-induced eosinophilia model.
    International archives of allergy and immunology, 1995, Volume: 106, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Atropine; Bronchial Hyperreactivity; Dextrans; Dose-Response Relationship, Drug; Imidazoles; Leukotriene D4; Lung; Male; Methysergide; Prostaglandin Endoperoxides, Synthetic; Pulmonary Eosinophilia; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane A2; Vasoconstrictor Agents

1995
Leukotriene-evoked cyclic chloride secretion is mediated by enteric neuronal modulation in guinea-pig colon.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:5

    Topics: Animals; Atropine; Bronchodilator Agents; Chlorides; Colon; Cyclooxygenase Inhibitors; Electric Stimulation; Electrophysiology; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Intestinal Mucosa; Leukotriene C4; Leukotriene D4; Neurons; Piroxicam; Tetrodotoxin

1997
A partial involvement of histamine in ultrasonically nebulized distilled water-induced bronchoconstriction in guinea-pigs.
    British journal of pharmacology, 1998, Volume: 125, Issue:4

    Topics: Administration, Inhalation; Animals; Atropine; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chlorpheniramine; Cromolyn Sodium; Diphenhydramine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Leukotriene D4; Male; Sonication; Water

1998
Nonselective cationic currents activated by acetylcholine in swine tracheal smooth muscle cells.
    Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:10

    Topics: Acetylcholine; Animals; Atropine; Bronchodilator Agents; Calcium; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Histamine; In Vitro Techniques; Ion Transport; Leukotriene D4; Membrane Potentials; Muscle, Smooth; Patch-Clamp Techniques; Pertussis Toxin; Swine; Trachea; Vasodilator Agents; Virulence Factors, Bordetella

1999
Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:3

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Atropine; Bronchi; Bronchodilator Agents; Capsaicin; Cholinergic Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histamine; Humans; In Vitro Techniques; Indomethacin; Leukotriene D4; Molecular Structure; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Peptides; Potassium Channels, Calcium-Activated; Propranolol; Prostaglandin D2; TRPV Cation Channels; Vasodilator Agents

2007
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
    Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan

2006