Page last updated: 2024-09-05

atropine and ketotifen

atropine has been researched along with ketotifen in 9 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(ketotifen)
Trials
(ketotifen)
Recent Studies (post-2010) (ketotifen)
26,7111,2591,6971,212275151

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)ketotifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.16
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.838
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.009
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.374
Alpha-2A adrenergic receptorHomo sapiens (human)2.187
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.112
Alpha-2B adrenergic receptorHomo sapiens (human)0.71
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)2.537
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.209
D(1A) dopamine receptorHomo sapiens (human)0.872
Histamine H2 receptorHomo sapiens (human)4.129
Alpha-1D adrenergic receptorHomo sapiens (human)3.727
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.031
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.16
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)2.537
Histamine H1 receptorHomo sapiens (human)0.0011
D(3) dopamine receptorHomo sapiens (human)1.963
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.046
5-hydroxytryptamine receptor 6Homo sapiens (human)1.141

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Owens, GR1
Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD1
Betancourt, A; Freerksen, N; Garfield, R; Günter, HH; Maul, H; Orise, P; Saade, G; Sohn, C; Vedernikov, Y; Wentz, M1
Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M1
He, P; Jin, X; Li, L; Min, Y; Song, B; Wang, Q1

Reviews

1 review(s) available for atropine and ketotifen

ArticleYear
New concepts in bronchodilator therapy.
    American family physician, 1986, Volume: 33, Issue:1

    Topics: Adrenal Cortex Hormones; Asthma; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Fenoterol; Humans; Ipratropium; Ketotifen; Lung Diseases, Obstructive; Sympathomimetics; Theophylline

1986

Other Studies

8 other study(ies) available for atropine and ketotifen

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
    Allergy, 1986, Volume: 41, Issue:7

    Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Male; Methysergide; Phthalazines; Pyridazines; Pyrilamine; SRS-A

1986
PAR-2 activating peptide-induced stimulation of pregnant rat myometrium contractile activity partly involves the other membrane receptors.
    European journal of obstetrics, gynecology, and reproductive biology, 2007, Volume: 130, Issue:1

    Topics: Animals; Atropine; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Hydrazines; Ibuprofen; In Vitro Techniques; Ketanserin; Ketotifen; Metabolic Networks and Pathways; Myometrium; Oligopeptides; Platelet Membrane Glycoproteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, G-Protein-Coupled; Receptors, Histamine H1; Receptors, Serotonin; Receptors, Thromboxane A2, Prostaglandin H2; Uterine Contraction

2007
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
    Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan

2006
The effects of the c-kit blocker glivec on the contractile response of urinary bladder.
    The Journal of surgical research, 2011, Volume: 171, Issue:2

    Topics: Animals; Atropine; Benzamides; Female; Histamine H1 Antagonists; Imatinib Mesylate; Interstitial Cells of Cajal; Ketotifen; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urodynamics

2011