Page last updated: 2024-09-05

atropine and isoniazid

atropine has been researched along with isoniazid in 31 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (isoniazid)	Trials (isoniazid)	Recent Studies (post-2010) (isoniazid)
26,711	1,259	1,697	21,815	960	4,493

Protein Interaction Comparison

Protein	Taxonomy	isoniazid (IC50)
Myeloperoxidase	Homo sapiens (human)	4.85
Enoyl-[acyl-carrier-protein] reductase [NADH]	Mycobacterium tuberculosis H37Rv	8.29
Putative FAD-containing monooxygenase MymA	Mycobacterium tuberculosis H37Rv	4.9

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (54.84)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (19.35)	29.6817
2010's	8 (25.81)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Beech, J	1
Reidenberg, MM	1
Tuttle, RS	2
Ganshorn, A; Kurz, H	1
Greengard, P; Quinn, GP; Reid, MB	1
Stoliarov, GV	1
Breunig, HL; Broadlick, DE; Comer, JP; Sampson, CB	1
Frank, RN; Green, WR; Ryan, SJ	1
Sidenur, VG	1
Arrell, RW	1
JOERGENSEN, G	1
FUJIMOTO, F	1
SEIFERT, G	1
Brzin, M; Erzen, I	1
Garcia Mendes, E; Scemes, E	1
BARRNETT, RJ; LENTZ, TL	1

Reviews

3 review(s) available for atropine and isoniazid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Principles of therapy. The Veterinary clinics of North America. Large animal practice, 1979, Volume: 1, Issue:1 Topics: Adrenal Cortex Hormones; Aerosols; Ampicillin; Animals; Atropine; Bronchodilator Agents; Chloramphenicol; Cromolyn Sodium; Horse Diseases; Horses; Isoniazid; Oxytetracycline; Penicillins; Pyrilamine; Respiratory Tract Diseases	1979
[PHARMACOGENETICS]. Die Medizinische Welt, 1964, Jan-04, Volume: 33 Topics: Abnormalities, Drug-Induced; Atropine; Cleft Palate; Cortisone; Genetics; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Isoniazid; Mutation; Oxidoreductases; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Primaquine; Thalidomide; Toxicology	1964

Other Studies

28 other study(ies) available for atropine and isoniazid

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Obesity and fasting--effects on drug metabolism and drug action in man. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:5 Pt 2 Topics: Adult; Animals; Antipyrine; Atropine; Blood Proteins; Fasting; Female; Humans; Isoniazid; Obesity; Pharmaceutical Preparations; Procaine; Protein Binding; Sulfisoxazole; Tolbutamide	1977
Relationship between blood histamine and centrally evoked hypotensive response. The American journal of physiology, 1965, Volume: 209, Issue:4 Topics: Animals; Atropine; Blood; Carotid Arteries; Cats; Chlorpheniramine; Histamine Release; Histidine; Hypotension; Iliac Artery; Isoniazid; Medulla Oblongata; p-Methoxy-N-methylphenethylamine; Physostigmine; Vasodilator Agents; Vasomotor System	1965
[Differences between the protein binding of newborns and adults and their importance for pharmacological action]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2 Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental	1968
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
[On the course of drug psychoses]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:3 Topics: Adrenocorticotropic Hormone; Adult; Atropine; Barbiturates; Chlorpromazine; Disulfiram; Drug Hypersensitivity; Female; Humans; Isoniazid; Male; Prednisolone; Psychoses, Substance-Induced; Quinacrine; Time Factors	1968
Estimation of mean potency and content uniformity of tablets: a new approach. Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:2 Topics: Atropine; Caffeine; Chemistry, Pharmaceutical; Computers; Diethylstilbestrol; Drug Compounding; Drug Tolerance; Isoniazid; Mestranol; Methyltestosterone; Models, Theoretical; Paramethasone; Pharmaceutical Preparations; Phenobarbital; Sulfates; Tablets	1970
Bilateral inflammatory pseudotumors of the ciliary body. American journal of ophthalmology, 1971, Volume: 72, Issue:3 Topics: Administration, Topical; Anti-Inflammatory Agents; Atropine; Biopsy; Ciliary Body; Diagnosis, Differential; Eye Diseases; Eye Neoplasms; Humans; Inflammation; Isoniazid; Lymphoma; Male; Melanoma; Middle Aged; Mycoses; Neoplasm Metastasis; Prednisolone; Prednisone; Sarcoidosis; Tuberculosis, Ocular	1971
Drug toxicity of genetic origin. Journal of the Indian Medical Association, 1969, Jan-01, Volume: 52, Issue:1 Topics: Atropine; Barbiturates; Catalase; Drug Hypersensitivity; Humans; Isoniazid; Primaquine; Succinylcholine	1969
Evidence for histaminergic nerves in the pyramidal cat. The American journal of physiology, 1966, Volume: 211, Issue:4 Topics: Animals; Atropine; Carbon Dioxide; Carotid Sinus; Cats; Chlorpheniramine; Histamine; Isoniazid; Norepinephrine; p-Methoxy-N-methylphenethylamine; Pyramidal Tracts; Reflex; Sympathetic Nervous System; Vasomotor System	1966
Acute tuberculous panophthalmitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1967, Volume: 78, Issue:1 Topics: Acetazolamide; Aged; Aminosalicylic Acids; Atropine; Choroid Neoplasms; Exophthalmos; Female; Glaucoma; Granuloma; Humans; Isoniazid; Male; Panophthalmitis; Retina; Tuberculosis, Ocular; Tuberculosis, Pulmonary; Uveitis	1967
[THE EFFECTS OF AUTONOMIC FUNCTION ON SERUM ISONIAZID CONCENTRATION AFTER IT'S ADMINISTRATION IN RABBITS]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1963, Nov-10, Volume: 52 Topics: Adrenocorticotropic Hormone; Atropine; Autonomic Nervous System; Blood Chemical Analysis; Chlorpromazine; Epinephrine; Imidazoles; Isoniazid; Neostigmine; Pharmacology; Physiology; Rabbits; Research; Reserpine; Tetraethylammonium Compounds; Tyramine	1963
[EXPERIMENTAL PATHOMORPHOLOGY OF THE SALIVARY DUCT SYSTEM]. Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1963, Volume: 47 Topics: Acid Phosphatase; Alkaline Phosphatase; Antineoplastic Agents; Atropine; Carbonic Anhydrases; Dihydrotachysterol; Electron Transport Complex II; Histocytochemistry; Iodides; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Norepinephrine; Pathology; Pharmacology; Pilocarpine; Rats; Research; Salivary Ducts; Salivary Glands; Serotonin; Succinate Dehydrogenase	1963
Cholinergic mechanisms in hydra. Comparative biochemistry and physiology. C: Comparative pharmacology, 1978, Volume: 59, Issue:1 Topics: Acetylcholine; Animals; Atropine; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Cholinesterases; Epinephrine; Hexamethonium Compounds; Hydra; Movement; Tubocurarine	1978
Cholinergic mechanism in Liriope tetraphylla (Cnidaria, Hydrozoa). Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 83, Issue:1 Topics: Animals; Atropine; Cholinesterases; Hydra; Receptors, Cholinergic; Synaptic Transmission; Time Factors	1986
THE ROLE OF THE NERVOUS SYSTEM IN REGENERATING HYDRA: THE EFFECT OF NEUROPHARMACOLOGICAL AGENTS. The Journal of experimental zoology, 1963, Volume: 154 Topics: Amphetamine; Amphetamines; Animals; Atropine; Autonomic Agents; Biphenyl Compounds; Chlorpromazine; Cnidaria; Decamethonium Compounds; Dihydroxyphenylalanine; Enzyme Inhibitors; Ergotamine; Hexamethonium Compounds; Histocytochemistry; Histology; Hydra; Isoflurophate; Lidocaine; Methyldopa; Nervous System; Pharmacology; Physostigmine; Regeneration; Research; Reserpine; Tubocurarine	1963