atropine has been researched along with idazoxan in 20 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (idazoxan) | Trials (idazoxan) | Recent Studies (post-2010) (idazoxan) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 1,499 | 40 | 123 |
| Protein | Taxonomy | atropine (IC50) | idazoxan (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0083 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0195 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0537 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 2.884 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0195 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Caló, G; Ferioli, V; Gaist, G; Morari, M | 1 |
| Barnes, PJ; Kuo, HP; Rogers, DF; Rohde, JA; Tokuyama, K | 1 |
| Loiacono, RE; Mitchelson, FJ | 1 |
| Ramage, AG; Tomlinson, A | 1 |
| Greenwood, B; Read, NW | 1 |
| Fozard, JR; Ramage, AG | 1 |
| Berridge, TL; Gadie, B; Roach, AG; Tulloch, IF | 1 |
| Beleslin, DB; Jovanović-Mićić, D; Samardzić, R | 1 |
| Amabeoku, GJ | 1 |
| Eisenach, JC; Pan, HL; Song, HK | 1 |
| Kimura, K; Kise, M; Masui, Y; Niida, H; Shirouchi, Y; Tajima, K; Ueda, F; Yamamoto, O | 1 |
| Chariot, J; Fu-Cheng, X; Rozé, C; Souli, A | 1 |
| Church, JE; Hodgson, WC | 1 |
| Conklin, D; Eisenach, JC; Obata, H | 1 |
| Corrêa, FM; Fernandes, KB; Resstel, LB | 1 |
| Honda, M; Ono, H; Takasu, K; Tanabe, M | 1 |
20 other study(ies) available for atropine and idazoxan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of [3H]choline and D-[3H]aspartate efflux from guinea pig and human neocortex.
Topics: Animals; Aspartic Acid; Atropine; Cerebral Cortex; Choline; Desipramine; Dioxanes; Electric Stimulation; Guinea Pigs; Humans; Idazoxan; Norepinephrine; Reference Values; Tritium | 1992 |
Neural control of goblet cell secretion in guinea pig airways.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Blood Pressure; Capsaicin; Dioxanes; Electric Stimulation; Epithelial Cells; Epithelium; Guinea Pigs; Idazoxan; Male; Mucous Membrane; Muscle, Smooth; Propranolol; Trachea; Vagus Nerve | 1990 |
Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices.
Topics: Acetylcholine; Aminoacridines; Animals; Atropine; Cerebral Cortex; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Nerve Endings; Nicotine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Tacrine; Tubocurarine | 1990 |
The effect of yohimbine, WY 26392 and idazoxan on sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Cats; Dioxanes; Dioxins; Dose-Response Relationship, Drug; Heart Rate; Idazoxan; Male; Quinolizines; Sympathetic Nervous System; Yohimbine | 1985 |
Neural control of jejunal and ileal motility and transmural potential difference in the ferret.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Brimonidine Tartrate; Dioxanes; Ferrets; Gastrointestinal Motility; Idazoxan; Ileum; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Muscle Contraction; Quinoxalines | 1986 |
Evidence that the putative 5-HT1A receptor agonists, 8-OH-DPAT and ipsapirone, have a central hypotensive action that differs from that of clonidine in anaesthetised cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Cats; Clonidine; Dioxanes; Heart Rate; Idazoxan; Male; Naphthalenes; Neurons; Pyrimidines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Trimethaphan; Vagotomy | 1987 |
alpha 2-Adrenoceptor agonists induced mydriasis in the rat by an action within the central nervous system.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Brain; Dioxins; Epinephrine; Guanabenz; Idazoxan; Injections, Intraventricular; Male; Mydriatics; Physostigmine; Pupil; Rats; Rats, Inbred Strains | 1983 |
The role of alpha-adrenergic mechanisms within the area postrema in dopamine-induced emesis.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Atropine; Cats; Cerebral Ventricles; Dioxanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Hemicholinium 3; Idazoxan; Injections, Intraventricular; Male; Mecamylamine; Methyltyrosines; Methysergide; Naloxone; Oxidopamine; Prazosin; Reserpine; Tolazoline; Tyrosine 3-Monooxygenase; Vomiting; Yohimbine | 1995 |
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Droxidopa; Drug Synergism; Idazoxan; Imipramine; Male; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phentolamine; Physostigmine; Prazosin; Reserpine; Seizures; Serotonin | 1993 |
Spinal nitric oxide mediates antinociception from intravenous morphine.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Atropine; Drug Interactions; Enzyme Inhibitors; Idazoxan; Injections, Intravenous; Male; Morphine; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Pain; Rats; Rats, Sprague-Dawley | 1998 |
Inhibition of stress-stimulated colonic propulsion by alpha 2-adrenoceptor antagonists in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Clonidine; Colon; Defecation; Gastrointestinal Motility; Gastrointestinal Transit; Idazoxan; Male; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Stress, Physiological; Yohimbine | 1998 |
Antisecretory effect of peptide YY through neural receptors in the rat jejunum in vitro.
Topics: Animals; Atropine; Haloperidol; Hexamethonium; Idazoxan; In Vitro Techniques; Jejunum; Male; Peptide YY; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin | 1999 |
Dose-dependent cardiovascular and neuromuscular effects of stonefish (Synanceja trachynis) venom.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atropine; Blood Pressure; Cardiovascular System; Chickens; Coronary Vessels; Fish Venoms; Fishes, Poisonous; Freeze Drying; Heart; Idazoxan; In Vitro Techniques; Muscarinic Antagonists; Muscle, Smooth, Vascular; Neuromuscular Blocking Agents; Propranolol; Quinolines; Rats; Reserpine; Swine | 2000 |
Spinal noradrenaline transporter inhibition by reboxetine and Xen2174 reduces tactile hypersensitivity after surgery in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Atropine; Behavior, Animal; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drosophila Proteins; Drug Interactions; Hyperalgesia; Idazoxan; Male; Morpholines; Muscarinic Antagonists; Pain Threshold; Pain, Postoperative; Peptides; Rats; Rats, Sprague-Dawley; Reboxetine; Snail Family Transcription Factors; Spinal Cord; Time Factors; Transcription Factors | 2005 |
alpha-Adrenergic and muscarinic cholinergic receptors are not involved in the modulation of the parasympathetic baroreflex by the medial prefrontal cortex in rats.
Topics: Animals; Atropine; Baroreflex; Cobalt; Dioxanes; Idazoxan; Male; Parasympathetic Nervous System; Phenylephrine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 2005 |
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine | 2006 |