atropine has been researched along with hydrochlorothiazide in 20 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (hydrochlorothiazide) | Trials (hydrochlorothiazide) | Recent Studies (post-2010) (hydrochlorothiazide) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 6,921 | 2,165 | 1,262 |
| Protein | Taxonomy | atropine (IC50) | hydrochlorothiazide (IC50) |
|---|---|---|---|
| Carbonic anhydrase 2 | Homo sapiens (human) | 5.4954 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chazov, EI | 1 |
| Bissett, JK; de Soyza, ND; Kane, JJ; Murphy, ML | 1 |
| Bonardi, G; Coppi, G; Gaetani, M | 1 |
| Doshchitsin, VL; Eremina, GA; Gratsianskii, NA | 1 |
| Smalley, HE | 1 |
| Bruzzese, T; Casadio, S; Coppi, G; Pala, G; Turba, C | 1 |
| Aminlari, A; Sassani, JW | 1 |
| Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR | 1 |
| Boeing, T; Cechinel-Filho, V; da Silva, LM; de Andrade, SF; de Souza, P; Krueger, CMA; Mariano, LNB; Schlickmann, F; Steimbach, VMB | 1 |
1 review(s) available for atropine and hydrochlorothiazide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
19 other study(ies) available for atropine and hydrochlorothiazide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[Treatment of rhythm and conduction disorders].
Topics: Adrenergic beta-Antagonists; Ajmaline; Arrhythmias, Cardiac; Atropine; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Inosine; Isoproterenol; Quinidine | 1975 |
Electrophysiology of atropine.
Topics: Adult; Aged; Atrioventricular Node; Atropine; Bundle of His; Bundle-Branch Block; Cardiac Catheterization; Electrocardiography; Electrophysiology; Heart; Heart Atria; Heart Conduction System; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Neural Conduction; Nitroglycerin; Purkinje Fibers; Refractory Period, Electrophysiological; Rheumatic Heart Disease; Tachycardia | 1975 |
Experimental gastric ulcers and uropepsinogen excretion in the rat.
Topics: Animals; Atropine; Carbon Tetrachloride; Endopeptidases; Enzyme Precursors; Female; Hydrochlorothiazide; Kidney Diseases; Male; Phenylbutazone; Prednisolone; Pyrimidines; Rats; Reserpine; Secretory Rate; Stomach Ulcer | 1971 |
[Atrioventricular blockade and its treatment in acute myocardial infarct].
Topics: Acute Disease; Administration, Oral; Aged; Atropine; Electric Stimulation Therapy; Electrocardiography; Female; Heart Block; Humans; Hydrochlorothiazide; Injections, Intravenous; Injections, Subcutaneous; Isoproterenol; Male; Monitoring, Physiologic; Myocardial Infarction; Prednisolone; Thiamine Pyrophosphate | 1973 |
Diagnosis and treatment of carbaryl poisoning in swine.
Topics: Animal Feed; Animals; Anorexia Nervosa; Antidotes; Ataxia; Atropine; Brain Edema; Carbamates; Humans; Hydrochlorothiazide; Muscular Diseases; Nervous System Diseases; Parasympathetic Nervous System; Swine; Swine Diseases | 1970 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chemistry, Organic; Chlorpromazine; Chlorpropamide; Cocaine; Cough; Diphenhydramine; Diuresis; Edema; Guinea Pigs; Hexamethonium Compounds; Histamine; Hydrochlorothiazide; Morphine; Naphthalenes; Nicotine; Organic Chemistry Phenomena; Phenylbutazone; Rats; Serotonin; Spasm | 1966 |
Simultaneous bilateral malignant glaucoma following laser iridotomy.
Topics: Atropine; Cyclopentolate; Female; Glaucoma, Angle-Closure; Humans; Hydrochlorothiazide; Intraocular Pressure; Iris; Laser Therapy; Middle Aged; Pilocarpine; Postoperative Complications; Visual Acuity | 1993 |
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY | 2014 |
Chemical composition and diuretic, natriuretic and kaliuretic effects of extracts of Mimosa bimucronata (DC.) Kuntze leaves and its majority constituent methyl gallate in rats.
Topics: Administration, Oral; Animals; Atropine; Cell Line; Disease Models, Animal; Diuretics; Gallic Acid; Hydrochlorothiazide; Hypertension; Male; Mice; Mimosa; Natriuretic Agents; Plant Extracts; Plant Leaves; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Muscarinic | 2017 |