Page last updated: 2024-09-05

atropine and glucagon-like peptide 1

atropine has been researched along with glucagon-like peptide 1 in 17 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(glucagon-like peptide 1)
Trials
(glucagon-like peptide 1)
Recent Studies (post-2010) (glucagon-like peptide 1)
26,7111,2591,6979,4841,2086,374

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)glucagon-like peptide 1 (IC50)
Glucagon-like peptide 1 receptorHomo sapiens (human)0.0051

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's6 (35.29)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawai, K; Koizumi, F; Ohashi, S; Ohneda, A; Ohneda, K; Ohneda, M; Suzuki, S1
Göke, B; Herrmann-Rinke, C; Hess, M; Vöge, A1
Göke, B; Herrmann-Rinke, C; Hörsch, D; McGregor, GP1
Balks, HJ; Brabant, G; Holst, JJ; von zur Mühlen, A1
Barcelo, A; Chayvialle, JA; Claustre, J; Cuber, JC; Moro, F; Plaisancié, P1
Göke, B; Herrmann-Rinke, C; McGregor, GP1
D'Alessio, DA; Havel, PJ; Kieffer, TJ; Taborsky, GJ1
Hansen, L; Holst, JJ; Lampert, S; Mineo, H1
Gulec, G; Isbil-Buyukcoskun, N1
Cam Etöz, B; Güleç, G; Işbil Büyükcoşkun, N; Ozlük, K1
Göke, B; Katschinski, M; Nicolaus, M; Schirra, J; Struckmeier, C; Woerle, HJ1
Cao, F; Chen, X; Kim, TH; Ma, N; Niu, G; Sun, Z; Tong, G1
Deacon, CF; Hartmann, B; Holst, JJ; Knop, FK; Plamboeck, A; Veedfald, S; Vilsbøll, T1
Agampodi, SB; Jayasumana, MACS; Rathish, D; Siribaddana, SH1
Kumari, P; Nakata, M; Otgon-Uul, Z; Yada, T; Zhang, BY1
Agampodi, S; Jayasumana, C; Rathish, D; Senavirathna, I; Siribaddana, S1
Agampodi, S; Jayasumana, C; Rathish, D1

Reviews

1 review(s) available for atropine and glucagon-like peptide 1

ArticleYear
In vivo, ex vivo and in vitro evidence for atropine-mediated attenuation of glucagon-like peptide-1 secretion: findings from a systematic review.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:29

    Topics: Adult; Animals; Atropine; Dipeptidyl Peptidase 4; Female; Glucagon-Like Peptide 1; Humans; Male; Mice; Postprandial Period; Rats; Swine

2019

Trials

2 trial(s) available for atropine and glucagon-like peptide 1

ArticleYear
GLP-1 regulates gastroduodenal motility involving cholinergic pathways.
    Neurogastroenterology and motility, 2009, Volume: 21, Issue:6

    Topics: Adult; Atropine; Autonomic Pathways; Blood Glucose; Double-Blind Method; Duodenum; Eating; Gastrointestinal Motility; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hormones; Humans; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Peptide Fragments; Receptors, Glucagon; Stomach

2009
The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Volume: 309, Issue:5

    Topics: Acetylcholine; Adult; Atropine; Blood Glucose; Denmark; Efferent Pathways; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Healthy Volunteers; Heart Rate; Humans; Infusions, Intravenous; Insulin; Male; Muscarinic Antagonists; Single-Blind Method; Somatostatin; Synaptic Transmission; Time Factors; Vagus Nerve; Young Adult

2015

Other Studies

14 other study(ies) available for atropine and glucagon-like peptide 1

ArticleYear
The structure-function relationship of GLP-1 related peptides in the endocrine function of the canine pancreas.
    The Tohoku journal of experimental medicine, 1991, Volume: 165, Issue:3

    Topics: Animals; Atropine; Dogs; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Peptide Fragments; Peptides; Protein Precursors; Structure-Activity Relationship

1991
Regulation of glucagon-like peptide-1 secretion from rat ileum by neurotransmitters and peptides.
    The Journal of endocrinology, 1995, Volume: 147, Issue:1

    Topics: Animals; Atropine; Bombesin; Cholinergic Agonists; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Ileum; In Vitro Techniques; Male; Neuropeptides; Neurotransmitter Agents; Peptide Fragments; Perfusion; Protein Precursors; Radioimmunoassay; Rats; Rats, Wistar; Secretory Rate; Stimulation, Chemical

1995
Galanin is a potent inhibitor of glucagon-like peptide-1 secretion from rat ileum.
    Peptides, 1996, Volume: 17, Issue:4

    Topics: Animals; Atropine; Galanin; Glucagon; Glucagon-Like Peptide 1; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Kinetics; Male; Methacholine Chloride; Neurons; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar

1996
Rapid oscillations in plasma glucagon-like peptide-1 (GLP-1) in humans: cholinergic control of GLP-1 secretion via muscarinic receptors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:3

    Topics: Adult; Atropine; Glucagon-Like Peptide 1; Glucose; Humans; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Peptides; Receptors, Muscarinic; Time Factors

1997
Effects of neurotransmitters, gut hormones, and inflammatory mediators on mucus discharge in rat colon.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Atropine; Bethanechol; Bombesin; Calcitonin Gene-Related Peptide; Colon; Enteric Nervous System; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Inflammation; Interleukin-1; Intestinal Mucosa; Isoproterenol; Lasalocid; Male; Mucus; Neurotransmitter Agents; Nitroprusside; Peptide Fragments; Peptide YY; Protein Precursors; Rats; Rats, Wistar; Serotonin; Tetrodotoxin; Vasoactive Intestinal Peptide

1998
Calcitonin gene-related peptide potently stimulates glucagon-like peptide-1 release in the isolated perfused rat ileum.
    Peptides, 2000, Volume: 21, Issue:3

    Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Female; Galanin; Glucagon; Glucagon-Like Peptide 1; Ileum; In Vitro Techniques; Kinetics; Peptide Fragments; Perfusion; Protein Precursors; Rats; Rats, Wistar

2000
Activation of the parasympathetic nervous system is necessary for normal meal-induced insulin secretion in rhesus macaques.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:3

    Topics: Animals; Atropine; Blood Glucose; Food; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Insulin; Insulin Secretion; Kinetics; Macaca mulatta; Male; Muscarinic Antagonists; Nicotinic Antagonists; Pancreatic Polypeptide; Parasympathetic Nervous System; Peptide Fragments; Protein Precursors; Trimethaphan

2001
Neural regulation of glucagon-like peptide-1 secretion in pigs.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:5

    Topics: Acetylcholine; Adrenergic Agents; Analysis of Variance; Animals; Atropine; Electric Stimulation; Enteric Nervous System; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Ileum; Isoproterenol; Neurotransmitter Agents; Norepinephrine; Organ Culture Techniques; Peptide Fragments; Phentolamine; Protein Precursors; Splanchnic Nerves; Swine; Vagus Nerve

2004
Investigation of the mechanisms involved in the central effects of glucagon-like peptide-1 on ethanol-induced gastric mucosal lesions.
    Regulatory peptides, 2005, May-15, Volume: 128, Issue:1

    Topics: Animals; Atropine; Cysteamine; Ethanol; Female; Gastric Mucosa; Glucagon-Like Peptide 1; Injections, Intraventricular; Mecamylamine; Muscarinic Antagonists; Nicotinic Antagonists; Peptides; Rats; Rats, Wistar

2005
Central effects of glucagon-like peptide-1 on cold-restraint stress-induced gastric mucosal lesions.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2007, Volume: 18, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Calcitonin Gene-Related Peptide; Cold Temperature; Enzyme Inhibitors; Gastric Mucosa; Glucagon-Like Peptide 1; Incretins; Indomethacin; Injections; Male; NG-Nitroarginine Methyl Ester; Parasympatholytics; Peptide Fragments; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological

2007
PEGylated exendin-4, a modified GLP-1 analog exhibits more potent cardioprotection than its unmodified parent molecule on a dose to dose basis in a murine model of myocardial infarction.
    Theranostics, 2015, Volume: 5, Issue:3

    Topics: Aminophylline; Animals; Atropine; Blotting, Western; Cardiovascular Agents; Disease Models, Animal; Drug Combinations; Exenatide; Glucagon-Like Peptide 1; Heart; Heart Function Tests; Histocytochemistry; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Nitroglycerin; Papaverine; Peptides; Phenobarbital; Survival Analysis; Treatment Outcome; Venoms

2015
From organophosphate poisoning to diabetes mellitus: The incretin effect.
    Medical hypotheses, 2016, Volume: 91

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Diabetes Mellitus, Type 2; Endocrine System; Glucagon-Like Peptide 1; Glucose; Homeostasis; Humans; Incretins; Models, Theoretical; Organophosphate Poisoning; Organophosphates; Treatment Outcome

2016
GLP-1 receptor agonist liraglutide exerts central action to induce β-cell proliferation through medulla to vagal pathway in mice.
    Biochemical and biophysical research communications, 2018, 05-15, Volume: 499, Issue:3

    Topics: Animals; Atropine; Brain Stem; Cell Proliferation; Feeding Behavior; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Hypothalamus; Injections, Intraventricular; Injections, Subcutaneous; Insulin-Secreting Cells; Liraglutide; Male; Medulla Oblongata; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Vagus Nerve

2018
A low GLP-1 response among patients treated for acute organophosphate and carbamate poisoning: a comparative cross-sectional study from an agrarian region of Sri Lanka.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:3

    Topics: Acetylcholinesterase; Acute Disease; Adult; Atropine; Carbamates; Chronic Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Erythrocytes; Female; Glucagon-Like Peptide 1; Humans; Incidence; Incretins; Insecticides; Male; Middle Aged; Occupational Exposure; Organophosphate Poisoning; Sri Lanka

2019