atropine has been researched along with furosemide in 48 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (furosemide) | Trials (furosemide) | Recent Studies (post-2010) (furosemide) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 13,631 | 1,358 | 2,486 |
| Protein | Taxonomy | atropine (IC50) | furosemide (IC50) |
|---|---|---|---|
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Homo sapiens (human) | 3.76 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Mus musculus (house mouse) | 3.76 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (33.33) | 18.7374 |
| 1990's | 8 (16.67) | 18.2507 |
| 2000's | 11 (22.92) | 29.6817 |
| 2010's | 13 (27.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Arneric, SP; Bai, S; Clarke, T; Fitzgerald, L; Gilligan, PJ; Grossman, S; Hartig, P; He, L; Heman, K; Krause, C; Lelas, S; Li, YW; Marshall, A; McElroy, JF; Miller, K; Robertson, D; Saye, J; Trainor, G; Ward, K; Wong, H; Zaczek, R; Zeller, K; Zhang, G | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Parekh, N; Peters, HJ; Popa, G | 1 |
| Castile, RG; Kleinberg, F | 1 |
| Barnes, PJ; Chung, KF; Elwood, W; Sakamoto, T | 1 |
| Hardcastle, J; Hardcastle, PT; Mathias, WJ | 1 |
| Cooke, HJ; Kuwahara, A | 1 |
| Dissing, S; Nauntofte, B | 1 |
| Mehmel, HC | 1 |
| Ernst, SA; Lowy, RJ | 1 |
| Carey, HV; Cooke, HJ | 2 |
| Dwyer, TM; Farley, JM; Yang, CM | 1 |
| Kudva, BT | 1 |
| Stock, E | 1 |
| Kusajima, K; Wax, ST; Webb, WR | 1 |
| Beck, OA; Hochrein, H; Krämer, KD | 1 |
| Formanek, K; Lindner, A; Selzer, H | 1 |
| Cohn, JN | 1 |
| Bleifeld, W; Hamm, CW; Kupper, W | 1 |
| Bucan, CA; Ray, SG; Soma, LR; Sweeney, CR | 1 |
| Hata, T; Sakamoto, K; Suzuki, H; Takeda, U; Yokota, M | 1 |
| Martini, JA; Maxson, AD; May, LL; Soma, LR | 1 |
| Demedts, MG; Pype, JL; Verleden, GM | 1 |
| Kuwahara, A; Kuwahara, Y; Mochizuki, T; Yanaihara, N | 1 |
| Hurley, TW; Moore, WC; Ryan, MP | 1 |
| Byrd, L; Cunningham-Smith, P; Manire, CA; Rhinehart, HL; Smith, DR | 1 |
| Asnar, DS; Colombari, DS; De Luca, LA; de Paula, PM; Menani, JV; Roncari, CF | 1 |
1 review(s) available for atropine and furosemide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
47 other study(ies) available for atropine and furosemide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Synthesis and structure-activity relationships of 8-(pyrid-3-yl)pyrazolo[1,5-a]-1,3,5-triazines: potent, orally bioavailable corticotropin releasing factor receptor-1 (CRF1) antagonists.
Topics: Administration, Oral; Animals; Behavior, Animal; Biological Availability; Clinical Trials as Topic; Dogs; Inhibitory Concentration 50; Rats; Receptors, Corticotropin-Releasing Hormone; Solubility; Structure-Activity Relationship; Triazines; Water | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Effects of adrenergic and cholinergic agents on ureteral functions in dogs.
Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Female; Furosemide; Male; Metaproterenol; Muscle Contraction; Muscle, Smooth; Neostigmine; Norepinephrine; Parasympathomimetics; Phentolamine; Pressure; Sympathomimetics; Ureter | 1979 |
The pathogenesis and management of massive pulmonary hemorrhage in the neonate. Case report of a normal survivor.
Topics: Asphyxia; Atropine; Blood Transfusion; Furosemide; Heart Failure; Hemorrhage; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lung Diseases; Male; Respiration, Artificial; Vitamin K | 1976 |
Pharmacological modulation of inhaled sodium metabisulphite-induced airway microvascular leakage and bronchoconstriction in the guinea-pig.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Bronchi; Bronchoconstriction; Capillary Permeability; Capsaicin; Chlorpheniramine; Female; Furosemide; Guinea Pigs; Nedocromil; Quinolones; Solanaceous Alkaloids; Sulfites | 1992 |
The influence of the gamma-amino butyric acid (GABA) antagonist bicuculline on transport processes in rat small intestine.
Topics: Animals; Atropine; Bicuculline; Biological Transport, Active; Electrodes; Electrophysiology; Furosemide; Intestine, Small; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin | 1991 |
Tachykinin-induced anion secretion in guinea pig distal colon: role of neural and inflammatory mediators.
Topics: Animals; Atropine; Chlorides; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Furosemide; Guinea Pigs; Histamine Release; In Vitro Techniques; Male; Pyrilamine; Substance P; Tachykinins; Tetrodotoxin | 1990 |
Na+ transport properties of isolated rat parotid acini.
Topics: Acetazolamide; Amiloride; Animals; Atropine; Biological Transport, Active; Bumetanide; Carbachol; Chlorides; Fluoresceins; Fluorescent Dyes; Furosemide; In Vitro Techniques; Kinetics; Male; Ouabain; Parotid Gland; Rats; Rats, Inbred Strains; Sodium | 1990 |
[Therapy of acute myocardial infarct].
Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Care; Diazepam; Digitalis Glycosides; Early Ambulation; First Aid; Furosemide; Heparin; Humans; Hypertension; Lidocaine; Myocardial Infarction; Nitroglycerin; Pacemaker, Artificial; Positive-Pressure Respiration; Sodium; Sodium Bicarbonate; Verapamil | 1985 |
Beta-adrenergic stimulation of ion transport in primary cultures of avian salt glands.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Atropine; Biological Transport, Active; Carbachol; Cells, Cultured; Colforsin; Cyclic GMP; Ducks; Epinephrine; Furosemide; Ions; Kinetics; Ouabain; Phentolamine; Propranolol; Salt Gland | 1987 |
Neuromodulation of intestinal transport in the suckling mouse.
Topics: 3-O-Methylglucose; Animals; Atropine; Electric Conductivity; Electric Stimulation; Epithelium; Female; Furosemide; Glucose; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Membrane Potentials; Methylglucosides; Mice; Tetrodotoxin | 1989 |
Acetylcholine-stimulated chloride flux in tracheal submucosal gland cells.
Topics: Acetylcholine; Animals; Atropine; Biological Transport; Calcium; Chlorides; Egtazic Acid; Electrochemistry; Exocrine Glands; Furosemide; Isoflurophate; Male; Mucus; ortho-Aminobenzoates; Ouabain; Pirenzepine; Swine; Trachea | 1988 |
Pharmacological analysis of 5-hydroxytryptamine actions on guinea-pig ileal mucosa.
Topics: Animals; Atropine; Chlorides; Cholinergic Fibers; Cisapride; Electric Conductivity; Electric Stimulation; Female; Furosemide; Guinea Pigs; Ileum; Intestinal Mucosa; Male; Piperidines; Secretory Rate; Serotonin; Tetrodotoxin | 1985 |
Atropine induced ventricular fibrillation in a case of diazinon poisoning.
Topics: Atropine; Diazinon; Furosemide; Humans; Insecticides; Oximes; Ventricular Fibrillation | 1985 |
Prophylactic total coronary care.
Topics: Arrhythmias, Cardiac; Atropine; Diet Therapy; Digoxin; Electrocardiography; Female; Furosemide; Heart Block; Heart Failure; Heparin; Hospitalization; Humans; Hypotension; Male; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Oxygen Inhalation Therapy; Progressive Patient Care; Shock, Cardiogenic | 1973 |
Effects of methylprednisolone on pulmonary microcirculation.
Topics: Animals; Atropine; Capillaries; Dogs; Female; Furosemide; Hemorrhage; Hypotension; Lung; Male; Methylprednisolone; Microcirculation; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Atelectasis; Pulmonary Circulation; Pulmonary Valve Insufficiency; Pulmonary Veins; Venous Pressure | 1974 |
[Suicidal digoxin intoxication with hyperkalaemia: report of a case (author's transl)].
Topics: Acute Disease; Adult; Atropine; Bradycardia; Digoxin; Electrocardiography; Female; Furosemide; Humans; Hyperkalemia; Intensive Care Units; Pacemaker, Artificial; Poisoning; Radioimmunoassay; Suicide | 1974 |
[Effect of spasmolytic agents on the bladder evacuation time in rats].
Topics: Animals; Atropine; Diuresis; Furosemide; Metabolic Clearance Rate; Papaverine; Parasympatholytics; Physostigmine; Rats; Strychnine; Time Factors; Urinary Bladder; Urination | 1971 |
Treatment of shock following myocardial infarction.
Topics: Atropine; Cardiac Glycosides; Furosemide; Humans; Isoproterenol; Metaraminol; Myocardial Infarction; Norepinephrine; Plasma Substitutes; Shock | 1969 |
[Therapy of acute myocardial infarct before hospital admission].
Topics: Aged; Atropine; Bradycardia; Cardiac Complexes, Premature; Diagnosis, Differential; First Aid; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Lidocaine; Myocardial Infarction; Nitroglycerin | 1982 |
Exercise-induced pulmonary hemorrhage in exercising Thoroughbreds: preliminary results with pre-exercise medication.
Topics: Animals; Atropine; Bronchodilator Agents; Cromolyn Sodium; Furosemide; Hemorrhage; Horse Diseases; Horses; Ipratropium; Lung Diseases; Male; Physical Exertion | 1984 |
[Ocular and auditory organs of Ochotona rufescens].
Topics: Animals; Animals, Laboratory; Atropine; Dogs; Ear, Inner; Electroretinography; Furosemide; Guinea Pigs; Kanamycin; Lagomorpha; Mammals; Pilocarpine; Pupil; Rats; Rats, Inbred Strains; Reflex, Acoustic; Retina | 1983 |
Effects of furosemide, exercise, and atropine on tracheal mucus transport rate in horses.
Topics: Aerosols; Animals; Atropine; Exercise Test; Female; Furosemide; Horses; Injections, Intravenous; Male; Mucous Membrane; Orchiectomy; Physical Exertion; Trachea | 1995 |
Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro.
Topics: Animals; Arginine; Atropine; Bumetanide; Chymotrypsin; Drug Therapy, Combination; Electric Stimulation; Female; Furosemide; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Nedocromil; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Premedication; Propranolol; Trachea; Vasoactive Intestinal Peptide | 1994 |
Action of pituitary adenylate cyclase-activating polypeptide on ion transport in guinea pig distal colon.
Topics: Animals; Atropine; Biological Transport; Chlorides; Colon; Dose-Response Relationship, Drug; Evoked Potentials; Furosemide; Guinea Pigs; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Ions; Male; Neurons; Neuropeptides; Peptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Tetrodotoxin; Vasoactive Intestinal Peptide | 1993 |
Regulation of changes in cytosolic Ca2+ and Na+ concentrations in rat submandibular gland acini exposed to carbachol and ATP.
Topics: Adenosine Triphosphate; Animals; Atropine; Benzofurans; Calcium; Carbachol; Chelating Agents; Cytoplasm; Egtazic Acid; Ethers, Cyclic; Fluorescent Dyes; Fura-2; Furosemide; Ionomycin; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Sodium; Submandibular Gland | 1996 |
Subacute atropine toxicity in a pygmy sperm whale, Kogia breviceps.
Topics: Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Diuretics; Drug Therapy, Combination; Fatal Outcome; Furosemide; Heart Rate; Male; Muscarinic Antagonists; Paralysis; Physostigmine; Pyloric Stenosis; Respiration; Whales | 2002 |
Involvement of central cholinergic mechanisms on sodium intake induced by gabaergic activation of the lateral parabrachial nucleus.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atropine; Captopril; Diuretics; Drinking; Eating; Furosemide; GABA Agonists; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic; Sodium Chloride | 2013 |