atropine has been researched along with fpl 55712 in 20 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (fpl 55712) | Trials (fpl 55712) | Recent Studies (post-2010) (fpl 55712) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 393 | 2 | 3 |
| Protein | Taxonomy | atropine (IC50) | fpl 55712 (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 1.58 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.51 | |
| Thromboxane-A synthase | Homo sapiens (human) | 10 | |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | 0.51 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 2.255 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (90.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Asakura, K; Kataura, A; Kojima, T; Narita, S; Shirasaki, H | 1 |
| Regal, JF | 1 |
| Hosokawa, T; Irinoda, K; Maruyama, Y; Misawa, M; Mizuno, H; Ohno, H; Sugimoto, K; Takahashi, Y; Yanaura, S; Yoshimura, K | 1 |
| Bánovcin, P; Hanácek, J; Korpás, J; Plank, L; Visnovský, P | 1 |
| Aizawa, H; Hakoda, H; Hirose, T; Ito, Y; Suzuki, H | 1 |
| Charette, L; Denis, D; Jones, TR | 1 |
| Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD | 1 |
| Benveniste, J; Brink, C; Haye-Legrand, I; Labat, C; Norel, X | 1 |
| Gobran, LI; Rooney, SA | 1 |
| Okamoto, M; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, K | 1 |
| Bell, RL; Regal, JF | 1 |
| Jones, TR; Masson, P | 1 |
| Burka, JF; Paterson, NA | 2 |
| Cade, JF; Clancy, RL; Pain, MC; Walker, SE | 1 |
| Casey, FB; Chakrin, LW; Hardy, TM; Regal, JF | 1 |
| Hammerbeck, DM; Swingle, KF | 1 |
| Alphin, RS; Callaham, EM; Foxwell, MH; Smith, WL; Yanni, JM | 1 |
| Abraham, WM; King, MM; Oliver, W; Wanner, A; Yerger, L | 1 |
1 review(s) available for atropine and fpl 55712
| Article | Year |
|---|---|
Effects of atropine, acetylsalicylic acid, FPL 55712, and phentolamine on increased histamine responsiveness of cat lung strips under conditions of airway inflammation.
Topics: Animals; Aspirin; Atropine; Bronchitis; Cats; Chromones; Constriction, Pathologic; Female; Histamine Release; In Vitro Techniques; Lung; Male; Phentolamine | 1989 |
19 other study(ies) available for atropine and fpl 55712
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.
Topics: Administration, Intranasal; Administration, Topical; Animals; Atropine; Benzenesulfonates; Capsaicin; Chromones; Coloring Agents; Diphenhydramine; Exudates and Transudates; Guinea Pigs; Histamine; Histamine Release; Injections, Subcutaneous; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Substance P | 1992 |
IgG vs IgE: mediators of antigen-induced guinea pig lung parenchymal contraction.
Topics: Animals; Antigens; Atropine; Chromones; Guinea Pigs; Histamine Release; Immunoglobulin E; Immunoglobulin G; Indomethacin; Lung; Male; Muscle Contraction; Pyrilamine; SRS-A | 1985 |
[Effects of flutropium bromide, a new antiasthma drug, on mediator release from mast cells and actions of mediators].
Topics: Animals; Asthma; Atropine; Atropine Derivatives; Chromones; Dogs; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Male; Mast Cells; Rats; Rats, Inbred Strains; Serotonin Antagonists; SRS-A | 1988 |
The spontaneous electrical and mechanical activity of human bronchial smooth muscle: its modulation by drugs.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Bronchi; Chromones; Electric Stimulation; Electrophysiology; Female; Humans; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Membrane Potentials; Middle Aged; Muscle Contraction; Muscle, Smooth; Physostigmine | 1989 |
Leukotriene and anti-IgE induced contractions of human isolated trachea: studies with leukotriene receptor antagonists and a novel 5-lipoxygenase inhibitor.
Topics: Animals; Antibodies, Anti-Idiotypic; Arachidonate Lipoxygenases; Atropine; Benzofurans; Chromones; Goats; Humans; In Vitro Techniques; Indomethacin; Keto Acids; Lipoxygenase Inhibitors; Muscle Contraction; Phenylbutyrates; Pyrilamine; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Sulfones; Trachea | 1988 |
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Male; Methysergide; Phthalazines; Pyridazines; Pyrilamine; SRS-A | 1986 |
Antigenic contraction of guinea pig tracheal preparations passively sensitized with monoclonal IgE: pharmacological modulation.
Topics: Animals; Antibodies, Monoclonal; Antigens; Atropine; Chromones; Dinitrophenols; Dose-Response Relationship, Immunologic; Guinea Pigs; Immunization, Passive; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Phenothiazines; Serum Albumin, Bovine; Trachea; Tripelennamine | 1988 |
Adenosine and leukotrienes have a regulatory role in lung surfactant secretion in the newborn rabbit.
Topics: Adenosine; Animals; Animals, Newborn; Atropine; Chromones; Phospholipids; Pilocarpine; Pulmonary Surfactants; Rabbits; Receptors, Purinergic; SRS-A; Theophylline | 1988 |
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; SRS-A; Tachyphylaxis | 1988 |
Mediators of C5a-induced bronchoconstriction in the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; Histamine; Indomethacin; Male; Phenylbutyrates; Pyrilamine; SRS-A | 1987 |
Comparative study of the pulmonary effects of intravenous leukotrienes and other bronchoconstrictors in anaesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Blood Pressure; Bronchi; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Lung; Male; Methysergide; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A; Timolol; Vagotomy | 1985 |
Inhibition of antigen-induced release of prostaglandin-like material from guinea-pig trachea by antihistamines FPL55712 and atropine.
Topics: Animals; Antigens; Atropine; Chromones; Ethers; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Male; Prostaglandins E; SRS-A; Trachea | 1980 |
The effects of SRS-A and histamine antagonists on antigen-induced contraction of guinea pig trachea.
Topics: Airway Resistance; Animals; Antigens; Atropine; Autacoids; Chromones; Drug Interactions; Ethers; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Male; Muscle Contraction; Trachea | 1981 |
Slow-reacting substance from alveolar macrophages--a mechanism of asthma?
Topics: Animals; Asthma; Atropine; Autacoids; Chromones; Cimetidine; Ethers; Guinea Pigs; Indomethacin; Macrophages; Methysergide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea | 1981 |
Effects of C5a on guinea pig lung: histamine release and mechanism of contraction.
Topics: Animals; Aspirin; Atropine; Chromones; Complement C5; Complement C5a; Dose-Response Relationship, Immunologic; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth | 1983 |
Use of a simple in vivo technique to investigate components of the immediate hypersensitivity reaction in conscious guinea pigs.
Topics: Aerosols; Anaphylaxis; Animals; Atropine; Bronchial Spasm; Chlorpheniramine; Chromones; Guinea Pigs; Hypersensitivity, Immediate; Indomethacin; Lipoxygenase; Male; Premedication; Prostaglandin-Endoperoxide Synthases | 1984 |
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response.
Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Expectorants; Hypersensitivity, Immediate; Immune Sera; Methods; Methysergide; Mucus; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains; Trachea | 1984 |
Effect of pharmacologic agents on antigen-induced decreases in specific lung conductance in sheep.
Topics: Airway Resistance; Animals; Antigens; Ascaris; Atropine; Bronchial Spasm; Chlorpheniramine; Chromones; Cromolyn Sodium; Ethers; Indomethacin; Metiamide; Respiratory Hypersensitivity; Sheep | 1981 |