Compounds > atropine
Page last updated: 2024-09-05

atropine and flupenthixol

atropine has been researched along with flupenthixol in 6 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(flupenthixol)		Trials
(flupenthixol)		Recent Studies (post-2010) (flupenthixol)
26,7111,2591,697929128138
26,7111,2591,69738018

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)flupenthixol (IC50)
Ubiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)7
Potassium channel subfamily K member 2Homo sapiens (human)2
DRattus norvegicus (Norway rat)0.003
D(3) dopamine receptorRattus norvegicus (Norway rat)0.003
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.003
D(4) dopamine receptorRattus norvegicus (Norway rat)0.003
D(2) dopamine receptorRattus norvegicus (Norway rat)0.003
WD repeat-containing protein 48Homo sapiens (human)7
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.0022

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, JA1
Christensen, AV; Nielsen, IM1
Andrews, PR; Craik, DJ; Martin, JL1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1

Other Studies

6 other study(ies) available for atropine and flupenthixol

ArticleYear
The effect of gamma-butyrolactone on locomotor activity in the rat.
    Psychopharmacology, 1978, Dec-15, Volume: 60, Issue:1

    Topics: 4-Butyrolactone; Animals; Atropine; Benztropine; Brain Chemistry; Clomipramine; Dopamine; Female; Flupenthixol; Furans; Motor Activity; Pentobarbital; Protriptyline; Rats; Time Factors

1978
Dopaminergic supersensitivity: influence of dopamine agonists, cholinergics, anticholinergics, and drugs used for the treatment of tardive dyskinesia.
    Psychopharmacology, 1979, Apr-11, Volume: 62, Issue:2

    Topics: Animals; Antiparkinson Agents; Apomorphine; Atropine; Dopamine; Drug Synergism; Dyskinesia, Drug-Induced; Flupenthixol; Humans; Male; Methylphenidate; Mice; Muscimol; Parasympatholytics; Parasympathomimetics; Phenobarbital; Physostigmine; Stereotyped Behavior

1979
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes

1999
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008