Page last updated: 2024-09-05

atropine and etomidate

atropine has been researched along with etomidate in 18 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(etomidate)
Trials
(etomidate)
Recent Studies (post-2010) (etomidate)
26,7111,2591,69719011
26,7111,2591,6972,071401576

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)etomidate (IC50)
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.0005
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.0009

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's1 (5.56)18.2507
2000's5 (27.78)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carlos, R; Innerarity, S1
Kay, B1
Siegmund, B; Sörgel, HJ1
Degryse, AD; Lagerweij, E; Ooms, L; van Dijk, P1
Löffler, B1
Jones, D; Laurence, AS; Thornton, JA1
Jost, U; Ruppert, M; Schmid, A1
Benson, GJ; Ko, JC; Olson, WA; Thurmon, JC; Tranquilli, WJ; Vaha-Vahe, AT1
Ernst, AA; Houry, D; Killeen, J; Marvez-Valls, E; Weiss, SJ1
Eger, EI; Laster, MJ; Sharma, M; Sonner, JM; Zhang, Y1
Antkowiak, B; Drexler, B; Grasshoff, C; Seeger, T; Thiermann, H1

Reviews

2 review(s) available for atropine and etomidate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Protocol for rapid sequence intubation in pediatric patients -- a four-year study.
    Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:4

    Topics: Adolescent; Androstanols; Atropine; Child; Child, Preschool; Clinical Protocols; Diagnosis-Related Groups; Drug Administration Schedule; Emergencies; Emergency Treatment; Etomidate; Female; Forms and Records Control; Humans; Hypnotics and Sedatives; Infant; Intubation, Intratracheal; Lidocaine; Louisiana; Male; Medical Records; Neuromuscular Nondepolarizing Agents; Retrospective Studies; Rocuronium; Succinylcholine; Thiopental; Trauma Centers

2002

Trials

3 trial(s) available for atropine and etomidate

ArticleYear
Effect of premedication on etomidate anaesthesia.
    British journal of anaesthesia, 1979, Volume: 51, Issue:12

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Atropine; Diazepam; Etomidate; Fentanyl; Humans; Imidazoles; Middle Aged; Pain; Preanesthetic Medication

1979
Total intravenous anaesthesia with etomidate-fentanyl. Use in general and gynaecological surgery.
    Anaesthesia, 1983, Volume: 38, Issue:1

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anesthesia, Intravenous; Atropine; Droperidol; Drug Administration Schedule; Etomidate; Female; Fentanyl; Humans; Imidazoles; Intraoperative Complications; Male; Middle Aged; Postoperative Complications

1983
Hemodynamic and anesthetic effects of etomidate infusion in medetomidine-premedicated dogs.
    American journal of veterinary research, 1994, Volume: 55, Issue:6

    Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Atropine; Dogs; Drug Combinations; Etomidate; Female; Hemodynamics; Imidazoles; Infusions, Intravenous; Male; Medetomidine; Premedication; Respiration; Safety

1994

Other Studies

13 other study(ies) available for atropine and etomidate

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Total intravenous anesthesia with etomidate. II. Evaluation of a practical technique for children.
    Acta anaesthesiologica Belgica, 1977, Volume: 28, Issue:2

    Topics: Adolescent; Anesthesia, Intravenous; Atropine; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Etomidate; Humans; Imidazoles; Injections, Intravenous; Pancuronium; Succinylcholine

1977
[Premedication for relaxed electroconvulsive therapy].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1987, Volume: 39, Issue:9

    Topics: Atropine; Dexamethasone; Electroconvulsive Therapy; Etomidate; Female; Humans; Male; Premedication; Psychotic Disorders; Succinylcholine

1987
Clinical, cardiovascular and respiratory effects of R8110 in premedicated dogs.
    Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:2

    Topics: Acepromazine; Anesthesia, General; Anesthetics; Animals; Atropine; Blood Gas Analysis; Blood Pressure; Dogs; Etomidate; Female; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Injections, Intravenous; Male; Methadone; Premedication; Respiration

1987
[Alfentanil in routine clinical use. A study of 50 patients].
    Der Anaesthesist, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia, General; Atropine; Blood Pressure; Child; Etomidate; Female; Fentanyl; Hemodynamics; Humans; Male; Methohexital; Middle Aged; Muscle Rigidity; Nitrous Oxide; Preanesthetic Medication; Thiopental

1985
[Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)].
    Der Anaesthesist, 1982, Volume: 31, Issue:1

    Topics: Adult; Aged; Anthracenes; Atropine; Benzodiazepines; Buprenorphine; Carticaine; Coma; Delirium; Etomidate; Fentanyl; Humans; Male; Meperidine; Midazolam; Parasympatholytics; Physostigmine; Preanesthetic Medication; Promethazine

1982
Blockade of acetylcholine receptors does not change the dose of etomidate required to produce immobility in rats.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Atropine; Etomidate; Immobilization; Male; Mecamylamine; Motor Activity; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Nicotinic

2007
Interactions between atropine and etomidate in cortical and spinal networks during cholinergic crisis.
    Toxicology letters, 2010, Oct-20, Volume: 198, Issue:3

    Topics: Acetylcholine; Action Potentials; Anesthetics, Intravenous; Animals; Atropine; Drug Interactions; Etomidate; Female; In Vitro Techniques; Mice; Muscarinic Antagonists; Neocortex; Nerve Net; Neurons; Pregnancy; Spinal Cord

2010