Page last updated: 2024-09-05

atropine and esmolol

atropine has been researched along with esmolol in 28 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(esmolol)
Trials
(esmolol)
Recent Studies (post-2010) (esmolol)
26,7111,2591,6971,023309266

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)esmolol (IC50)
Beta-1 adrenergic receptorHomo sapiens (human)0.197

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (35.71)18.2507
2000's12 (42.86)29.6817
2010's6 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Caracciolo, E; Chinitz, L; Demopoulos, L; Perez, J; Schrem, S; Schwartzman, D; Slater, W1
Burton, MD; Johnson, DC; Kazemi, H1
Elghozi, JL; Escourrou, P; Januel, B; Laude, D1
Bernardi, L; Bianchini, B; Calciati, A; Leuzzi, S; Marchesi, E; Passino, C; Rinaldi, M; Spadacini, G; Valle, F; Viganó, M1
Arone, LJ; Hirsch, J; Leibel, RL; Mackintosh, R; Rosenbaum, M1
Dürsch, M; König, S; Neuzner, J; Pitschner, H; Wilhelmy, R2
Chen, C; Chen, L; Chen, M; de Prada, VA; Feng, YJ; Gillam, L; Ma, L; Waters, D1
Garcia, MJ; Koch, R; Lang, RM; Mor-Avi, V; Spencer, KT; Vignon, P; Weinert, L1
Arrone, LJ; Hirsch, J; Leibel, RL; Mackintosh, R; Rosenbaum, M1
Aronne, LJ; Hirsch, J; Mackintosh, RM1
Cooklin, M; Gold, MR; Kavesh, N; Kirk, M; MacMurdy, K; Peters, RW; Rashba, EJ; Sarang, S; Shorofsky, SR1
Hou, Y; Jackman, WM; Lazzara, R; Schauerte, P; Scherlag, BJ; Scherlag, M; Sun, YX; Yamanashi, WS1
Frakes, MA1
Lighthall, G; Robinson, M1
Bleich, M; Brendel, J; Busch, AE; Knobloch, K; Rosenstein, B; Wirth, KJ1
Claydon, R; Hall, A; Haydon, TP1
Guo, JH; Jackman, WM; Jiang, H; Lazzara, R; Lin, J; Lu, Z; Niu, G; Po, SS; Scherlag, BJ; Yu, L1
Calame, J; Calame, S; Gallo, A; Habel, N; Lustgarten, DL; Müller, JG; Noori, A; Sobel, BE; Spector, PS; Thompson, N; Znojkiewicz, P1
Fan, Y; Hepler, E; Huang, H; Liu, Y; Male, S; Mao, J; Po, SS; Scherlag, BJ; Varma, V; Xia, W1
Buchholz, B; Del Mauro, JS; Deutsch, ACR; Donato, M; Gelpi, RJ; Höcht, C; Perez, V; Rodríguez, M1

Reviews

2 review(s) available for atropine and esmolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Rapid sequence induction medications: an update.
    Journal of emergency nursing, 2003, Volume: 29, Issue:6

    Topics: Adrenergic beta-Antagonists; Anesthetics; Atropine; Barbiturates; Drug Therapy, Combination; Emergency Nursing; Fentanyl; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Lidocaine; Narcotics; Neuromuscular Blocking Agents; Oxygen Inhalation Therapy; Paralysis; Propanolamines; Succinylcholine

2003

Trials

5 trial(s) available for atropine and esmolol

ArticleYear
Effect of autonomic blockade on heart rate and blood pressure in sleep apnea syndrome.
    Blood pressure, 1995, Volume: 4, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Blood Pressure; Heart Rate; Humans; Male; Muscarinic Antagonists; Nicergoline; Parasympathetic Nervous System; Propanolamines; Respiratory Physiological Phenomena; Sleep Apnea Syndromes

1995
Selective and unselective blockade of sympathicus and parasympathicus and vagal enhancement by pirenzepine: effects on heart rate and heart rate variability in healthy subjects.
    Clinical science (London, England : 1979), 1996, Volume: 91 Suppl

    Topics: Adrenergic beta-Antagonists; Adult; Atropine; Autonomic Nervous System; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Neuromuscular Blocking Agents; Parasympatholytics; Pirenzepine; Propanolamines; Signal Processing, Computer-Assisted

1996
Patients with AV nodal reentrant tachycardias show a reduced vagal impact on heart rate compared to healthy subjects with further decrease of vagal tone after radiofrequency catheter modification.
    Clinical science (London, England : 1979), 1996, Volume: 91 Suppl

    Topics: Adrenergic beta-Antagonists; Adult; Atropine; Catheter Ablation; Female; Heart Rate; Humans; Male; Middle Aged; Parasympatholytics; Pirenzepine; Propanolamines; Sympathetic Nervous System; Tachycardia, Atrioventricular Nodal Reentry

1996
The effects of drugs used to treat obesity on the autonomic nervous system.
    Obesity research, 2000, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Appetite Depressants; Atropine; Autonomic Nervous System; Basal Metabolism; Calorimetry; Creatinine; Cyclobutanes; Dexfenfluramine; Dopamine; Epinephrine; Heart Rate; Humans; Male; Norepinephrine; Obesity; Parasympatholytics; Phentermine; Propanolamines; Serotonin Receptor Agonists; Single-Blind Method

2000
Effects of selective autonomic blockade on T-wave alternans in humans.
    Circulation, 2002, Feb-19, Volume: 105, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atropine; Autonomic Nervous System; Cardiac Pacing, Artificial; Coronary Artery Disease; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Parasympathetic Nervous System; Parasympatholytics; Propanolamines; Prospective Studies; Sympathetic Nervous System; Sympatholytics; Tachycardia, Ventricular; Ventricular Dysfunction, Left

2002

Other Studies

21 other study(ies) available for atropine and esmolol

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Autonomic manipulation influences both temporal and frequency analyses of late potentials.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2

    Topics: Adrenergic beta-Antagonists; Atropine; Electrocardiography; Female; Heart Conduction System; Humans; Isoproterenol; Male; Middle Aged; Myocardial Infarction; Propanolamines; Signal Processing, Computer-Assisted

1992
Adrenergic and cholinergic interaction in central ventilatory control.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:5

    Topics: Acetylcholine; Animals; Atropine; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Colforsin; Cyclic AMP; Dogs; Isoproterenol; Medulla Oblongata; Propanolamines; Receptors, Adrenergic; Receptors, Cholinergic; Respiration; Respiratory Center; Second Messenger Systems; Yohimbine

1990
Demonstrable cardiac reinnervation after human heart transplantation by carotid baroreflex modulation of RR interval.
    Circulation, 1995, Nov-15, Volume: 92, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Atropine; Baroreflex; Carotid Arteries; Electrocardiography; Heart; Heart Rate; Heart Transplantation; Humans; Middle Aged; Parasympatholytics; Pressoreceptors; Propanolamines; Suction; Sympathetic Nervous System

1995
Autonomic nervous system activity in weight gain and weight loss.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 2

    Topics: Adrenergic beta-Antagonists; Adult; Atropine; Autonomic Nervous System; Energy Metabolism; Female; Heart Conduction System; Heart Rate; Humans; Infusions, Parenteral; Male; Obesity; Peripheral Nerves; Propanolamines; Reference Values; Sympathetic Nervous System; Weight Gain

1995
Effects of beta-blockade and atropine on ischemic responses in left ventricular regions subtending coronary stenosis during dobutamine stress echocardiography.
    Journal of the American College of Cardiology, 1996, Volume: 28, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Atropine; Cardiotonic Agents; Coronary Circulation; Coronary Disease; Dobutamine; Echocardiography; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Observer Variation; Oxygen Consumption; Propanolamines; Sensitivity and Specificity; Swine; Ventricular Function, Left

1996
Segmental analysis of color kinesis images: new method for quantification of the magnitude and timing of endocardial motion during left ventricular systole and diastole.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Algorithms; Atropine; Color; Diastole; Dobutamine; Echocardiography; Endocardium; Feasibility Studies; Female; Humans; Image Processing, Computer-Assisted; Male; Motion; Muscarinic Antagonists; Propanolamines; Reference Values; Systole; Ventricular Function, Left

1997
Cardiac autonomic nervous system activity in obese and never-obese young men.
    Obesity research, 1997, Volume: 5, Issue:4

    Topics: Adult; Atropine; Autonomic Nervous System; Electrocardiography; Heart; Humans; Male; Obesity; Parasympatholytics; Propanolamines; Sympatholytics

1997
Endovascular stimulation within the left pulmonary artery to induce slowing of heart rate and paroxysmal atrial fibrillation.
    Cardiovascular research, 2002, Volume: 54, Issue:2

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Atrial Fibrillation; Atropine; Autonomic Nervous System; Disease Models, Animal; Dogs; Electric Stimulation; Electrocardiography; Endothelium, Vascular; Heart Rate; Muscarinic Antagonists; Propanolamines; Propranolol; Pulmonary Artery

2002
Asystole during successive electroconvulsive therapy sessions: a report of two cases.
    Journal of clinical anesthesia, 2004, Volume: 16, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atropine; Bradycardia; Catatonia; Depressive Disorder; Dose-Response Relationship, Drug; Electrocardiography; Electroconvulsive Therapy; Heart Arrest; Heart Rate; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Propanolamines; Retreatment

2004
Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:7

    Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Biphenyl Compounds; Chromans; Flecainide; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Propafenone; Propanolamines; Sotalol; Sulfonamides; Swine; Ventricular Function

2004
Transient transmural ischaemia during endobronchial laser treatment: possible coronary artery embolism.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:5

    Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atropine; Bronchoscopy; Coronary Vessels; Diagnosis, Differential; Electrocardiography; Embolism, Air; Ephedrine; Female; Heart Rate; Humans; Hypotension; Laser Therapy; Lung Neoplasms; Metaraminol; Middle Aged; Monitoring, Intraoperative; Myocardial Ischemia; Ovarian Neoplasms; Propanolamines

2008
Autonomic mechanism for initiation of rapid firing from atria and pulmonary veins: evidence by ablation of ganglionated plexi.
    Cardiovascular research, 2009, Nov-01, Volume: 84, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Atrial Fibrillation; Atropine; Autonomic Denervation; Cardiac Pacing, Artificial; Catheter Ablation; Disease Models, Animal; Dogs; Electrophysiologic Techniques, Cardiac; Ganglia, Autonomic; Heart Atria; Injections, Intravenous; Muscarinic Antagonists; Propanolamines; Pulmonary Veins

2009
The impact of pharmacologic sympathetic and parasympathetic blockade on atrial electrogram characteristics in patients with atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 2011, Volume: 34, Issue:11

    Topics: Adrenergic beta-1 Receptor Antagonists; Atrial Fibrillation; Atropine; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Nerve Block; Parasympatholytics; Propanolamines; Sympathetic Nervous System; Sympatholytics; Treatment Outcome

2011
Experimental model of focal atrial tachycardia: clinical correlates.
    Journal of cardiovascular electrophysiology, 2013, Volume: 24, Issue:8

    Topics: Animals; Atropine; Disease Models, Animal; Dogs; Electric Stimulation; Electrophysiologic Techniques, Cardiac; Epinephrine; Heart Conduction System; Propanolamines; Tachycardia, Supraventricular

2013
Changes in the loading conditions induced by vagal stimulation modify the myocardial infarct size through sympathetic-parasympathetic interactions.
    Pflugers Archiv : European journal of physiology, 2015, Volume: 467, Issue:7

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Atropine; Catecholamines; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Propanolamines; Proto-Oncogene Proteins c-akt; Rabbits; Reflex; Signal Transduction; Sympathetic Nervous System; Vagus Nerve

2015