Page last updated: 2024-09-05

atropine and erythromycin

atropine has been researched along with erythromycin in 47 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (erythromycin)	Trials (erythromycin)	Recent Studies (post-2010) (erythromycin)
26,711	1,259	1,697	14,524	1,138	1,926

Protein Interaction Comparison

Protein	Taxonomy	erythromycin (IC50)
30S ribosomal protein S6	Escherichia coli K-12	1.156
30S ribosomal protein S7	Escherichia coli K-12	1.156
50S ribosomal protein L15	Escherichia coli K-12	1.156
Cytochrome P450 3A4	Homo sapiens (human)	1.045
50S ribosomal protein L10	Escherichia coli K-12	1.156
50S ribosomal protein L11	Escherichia coli K-12	1.156
50S ribosomal protein L7/L12	Escherichia coli K-12	1.156
50S ribosomal protein L19	Escherichia coli K-12	1.156
50S ribosomal protein L1	Escherichia coli K-12	1.156
50S ribosomal protein L20	Escherichia coli K-12	1.156
50S ribosomal protein L27	Escherichia coli K-12	1.156
50S ribosomal protein L28	Escherichia coli K-12	1.156
50S ribosomal protein L29	Escherichia coli K-12	1.156
50S ribosomal protein L31	Escherichia coli K-12	1.156
50S ribosomal protein L31 type B	Escherichia coli K-12	1.156
50S ribosomal protein L32	Escherichia coli K-12	1.156
50S ribosomal protein L33	Escherichia coli K-12	1.156
50S ribosomal protein L34	Escherichia coli K-12	1.156
50S ribosomal protein L35	Escherichia coli K-12	1.156
50S ribosomal protein L36	Escherichia coli K-12	1.156
30S ribosomal protein S10	Escherichia coli K-12	1.156
30S ribosomal protein S11	Escherichia coli K-12	1.156
30S ribosomal protein S12	Escherichia coli K-12	1.156
30S ribosomal protein S13	Escherichia coli K-12	1.156
30S ribosomal protein S16	Escherichia coli K-12	1.156
30S ribosomal protein S18	Escherichia coli K-12	1.156
30S ribosomal protein S19	Escherichia coli K-12	1.156
30S ribosomal protein S20	Escherichia coli K-12	1.156
30S ribosomal protein S2	Escherichia coli K-12	1.156
30S ribosomal protein S3	Escherichia coli K-12	1.156
30S ribosomal protein S4	Escherichia coli K-12	1.156
30S ribosomal protein S5	Escherichia coli K-12	1.156
30S ribosomal protein S8	Escherichia coli K-12	1.156
30S ribosomal protein S9	Escherichia coli K-12	1.156
50S ribosomal protein L13	Escherichia coli K-12	1.156
50S ribosomal protein L14	Escherichia coli K-12	1.156
50S ribosomal protein L16	Escherichia coli K-12	1.156
50S ribosomal protein L23	Escherichia coli K-12	1.156
30S ribosomal protein S15	Escherichia coli K-12	1.156
50S ribosomal protein L17	Escherichia coli K-12	1.156
50S ribosomal protein L21	Escherichia coli K-12	1.156
50S ribosomal protein L30	Escherichia coli K-12	1.156
50S ribosomal protein L6	Escherichia coli K-12	1.156
30S ribosomal protein S14	Escherichia coli K-12	1.156
30S ribosomal protein S17	Escherichia coli K-12	1.156
30S ribosomal protein S1	Escherichia coli K-12	1.156
50S ribosomal protein L18	Escherichia coli K-12	1.156
50S ribosomal protein L2	Escherichia coli K-12	1.156
50S ribosomal protein L3	Escherichia coli K-12	1.156
50S ribosomal protein L24	Escherichia coli K-12	1.156
50S ribosomal protein L4	Escherichia coli K-12	1.156
50S ribosomal protein L22	Escherichia coli K-12	1.156
50S ribosomal protein L5	Escherichia coli K-12	1.156
30S ribosomal protein S21	Escherichia coli K-12	1.156
50S ribosomal protein L25	Escherichia coli K-12	1.156
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	0.039
50S ribosomal protein L36 2	Escherichia coli K-12	1.156

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (10.64)	18.7374
1990's	19 (40.43)	18.2507
2000's	14 (29.79)	29.6817
2010's	9 (19.15)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Forth, W; Holle, GE; Steinbach, E	1
Bosso, R; Fiorucci, S; Morelli, A	1
Jansen, JB; Jebbink, MC; Lamers, CB; Masclee, AA; Rovati, LC; Schipper, J; van der Kleij, FG	1
Bosso, R; Bottini, P; Desando, A; Fiorucci, S; Marino, C; Morelli, A; Scionti, L	1
Baker, RA; Costi, D; Saccone, GT; Thune, A; Toouli, J	1
Inatomi, N; Itoh, Z; Marui, S; Omura, S; Satoh, H; Satoh, T	1
Hashimoto, N; Inatomi, N; Itoh, Z; Maki, Y; Omura, S; Satoh, H	1
Wakabayashi, K; Yamada, S	1
Bellows, AR; Grant, WM	1
Boruchoff, SA; Dohlman, CH	1
Inoue, M; Itoh, Z; Mitsuhashi, S; Nakaya, M; Suzuki, T	1
Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O	1
Bruley des Varannes, S; Chayvialle, JA; Galmiche, JP; Parys, V; Ropert, A; Rozé, C	1
Falcucci, M; Grossi, L; Lapenna, D; Martelli, L; Marzio, L	1
Pilot, MA; Qin, XY; Scott, M; Thompson, H	1
Inatomi, N; Itoh, Z; Omura, S; Satoh, H; Satoh, T	1
Fiorucci, S; Morelli, A	1
Hayashi, N; Itoh, Z; Mizumoto, A; Ohtawa, M; Omura, S; Yanagida, K	1
Inui, A; Itoh, Z; Mizumoto, A; Omura, S; Satoh, M; Shiba, Y	1
Arruebo, MP; Murillo, MD; Plaza, MA	1
Arruebo, MP; Guerrero-Lindner, E; Murillo, MD; Plaza, MA	1
Costa, A; Crema, F; d'Angelo, L; De Ponti, F; Gibelli, G	1
Andrews, FM; Doherty, TJ; Frazier, DL; Provenza, MK	1
Coulie, B; Janssens, J; Peeters, T; Tack, J	1
Inatomi, N; Itoh, Z; Marui, S; Omura, S; Sato, F	1
Gonzalez, A; Ryan, RP; Sarna, SK	1
Athanasakis, H; Chrysos, E; Epanomeritakis, E; Koutsoumbi, P; Tsiaoussis, J; Vassilakis, JS; Xynos, E; Zoras, O	1
Burton, DD; Camilleri, M; Kim, DY; Klein, PD; Lee, JS; Stephens, D; Thomforde, GM; Viramontes, BE; Zinsmeister, AR	1
Asao, T; Haga, N; Kamiyama, Y; Kuwano, H; Mochiki, E; Nakabayashi, T	1
Elliott, RA; England, RC; Norman, RI	1
Baxter, K; Burton, D; Camilleri, M; Castillo, EJ; Cremonini, F; Delgado-Aros, S; Ferber, I; Stephens, D; Zinsmeister, AR	1
Itoh, Z; Koga, H; Omura, S; Ozaki, K; Takanashi, H; Yogo, K	1
Hoshino, S; Koike, K; Oda, S; Sakahara, S; Sakai, T; Sakata, I; Takahashi, T; Xie, Z	1

Reviews

2 review(s) available for atropine and erythromycin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Penetrating keratoplasty. International ophthalmology clinics, 1968,Fall, Volume: 8, Issue:3 Topics: Adrenal Cortex Hormones; Anesthesia, Local; Anterior Chamber; Atropine; Cataract Extraction; Cornea; Corneal Injuries; Corneal Transplantation; Edema; Erythromycin; Eye Diseases; Hospitalization; Humans; Intraocular Pressure; Methods; Phenylephrine; Postoperative Care; Preoperative Care; Prognosis; Refraction, Ocular; Suture Techniques; Tissue Donors; Tissue Preservation; Transplantation, Autologous; Transplantation, Homologous; Visual Acuity	1968

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Penetrating keratoplasty.

International ophthalmology clinics, 1968,Fall, Volume: 8, Issue:3

Topics: Adrenal Cortex Hormones; Anesthesia, Local; Anterior Chamber; Atropine; Cataract Extraction; Cornea; Corneal Injuries; Corneal Transplantation; Edema; Erythromycin; Eye Diseases; Hospitalization; Humans; Intraocular Pressure; Methods; Phenylephrine; Postoperative Care; Preoperative Care; Prognosis; Refraction, Ocular; Suture Techniques; Tissue Donors; Tissue Preservation; Transplantation, Autologous; Transplantation, Homologous; Visual Acuity

1968

Trials

5 trial(s) available for atropine and erythromycin

Article	Year
Erythromycin enhances fasting and postprandial proximal gastric tone in humans. Gastroenterology, 1995, Volume: 109, Issue:1 Topics: Adult; Analysis of Variance; Atropine; Eating; Erythromycin; Fasting; Female; Humans; Infusions, Intravenous; Male; Motilin; Muscle Contraction; Regression Analysis; Stimulation, Chemical; Stomach	1995
Involvement of two different pathways in the motor effects of erythromycin on the gastric antrum in humans. Gut, 1998, Volume: 43, Issue:3 Topics: Anti-Bacterial Agents; Atropine; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythromycin; Gastrointestinal Motility; Humans; Manometry; Muscarinic Antagonists; Myoelectric Complex, Migrating; Pyloric Antrum; Serotonin Antagonists; Sumatriptan	1998
The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. The American journal of gastroenterology, 2000, Volume: 95, Issue:12 Topics: Adult; Atropine; Double-Blind Method; Erythromycin; Esophagus; Female; Gastrointestinal Agents; Humans; Male; Manometry; Ondansetron; Peristalsis; Receptors, Serotonin	2000
Validation of a stable isotope gastric emptying test for normal, accelerated or delayed gastric emptying. Neurogastroenterology and motility, 2001, Volume: 13, Issue:6 Topics: Adolescent; Adult; Aging; Algorithms; Anti-Bacterial Agents; Atropine; Bacterial Proteins; Breath Tests; Carbon Dioxide; Carbon Isotopes; Erythromycin; Female; Gastric Emptying; Humans; Linear Models; Male; Middle Aged; Models, Statistical; Parasympatholytics; Sex Characteristics; Spirulina	2001
Effect of gastric volume or emptying on meal-related symptoms after liquid nutrients in obesity: a pharmacologic study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:10 Topics: Adolescent; Adult; Aged; Atropine; Double-Blind Method; Erythromycin; Female; Gastric Emptying; Humans; Male; Middle Aged; Obesity; Pancreatic Polypeptide; Regression Analysis; Stomach	2005

Other Studies

40 other study(ies) available for atropine and erythromycin

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effects of erythromycin in the dog upper gastrointestinal tract. The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 1 Topics: Animals; Atropine; Digestive System; Dogs; Electrophysiology; Erythromycin; Female; Ganglionic Blockers; Gastrointestinal Diseases; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Male; Neostigmine	1992
Erythromycin stimulates gallbladder emptying and motilin release by atropine-sensitive pathways. Digestive diseases and sciences, 1992, Volume: 37, Issue:11 Topics: Adult; Analysis of Variance; Atropine; Dose-Response Relationship, Drug; Erythromycin; Fasting; Female; Gallbladder; Gallbladder Emptying; Humans; Male; Middle Aged; Motilin; Reference Values; Somatostatin; Time Factors; Ultrasonography	1992
Effect of loxiglumide and atropine on erythromycin-induced reduction in gallbladder volume in human subjects. Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:4 Topics: Adult; Atropine; Cholecystokinin; Erythromycin; Female; Gallbladder; Humans; Male; Pancreatic Polypeptide; Proglumide; Pulse; Ultrasonography	1992
Effect of erythromycin on gallbladder emptying in diabetic patients with and without autonomic neuropathy and high levels of motilin. Digestive diseases and sciences, 1992, Volume: 37, Issue:11 Topics: Adult; Analysis of Variance; Atropine; Autonomic Nervous System Diseases; Diabetic Neuropathies; Erythromycin; Female; Gallbladder; Gallbladder Emptying; Heart Diseases; Humans; Male; Motilin; Ultrasonography	1992
Motilin and erythromycin enhance the in vitro contractile activity of the sphincter of Oddi of the Australian brush-tailed possum. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:1 Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Electrophysiology; Erythromycin; Gallbladder; Motilin; Muscle Contraction; Muscle, Smooth; Opossums; Sphincter of Oddi	1992
EM-523, an erythromycin derivative, and motilin show similar contractile activity in isolated rabbit intestine. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:3 Topics: Acetylcholine; Animals; Atropine; Dinoprost; Drug Interactions; Erythromycin; Female; Guinea Pigs; Intestine, Small; Male; Motilin; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Tetrodotoxin	1990
An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2 Topics: Animals; Atropine; Dogs; Erythromycin; Fasting; Gastrointestinal Motility; Male; Motilin; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Vomiting	1989
Effects of several macrolide antibiotics on blood pressure of dogs. Japanese journal of pharmacology, 1972, Volume: 22, Issue:6 Topics: Animals; Anti-Bacterial Agents; Atropine; Biological Assay; Blood Pressure; Cordotomy; Diphenhydramine; Dogs; Erythromycin; Female; Glycosides; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Lactones; Leucomycins; Male; Muscle Contraction; Oleandomycin; Parasympathetic Nervous System; Sympathectomy; Tachyphylaxis; Vagotomy	1972
Cyclocryotherapy in advanced inadequately controlled glaucoma. American journal of ophthalmology, 1973, Volume: 75, Issue:4 Topics: Adolescent; Adult; Aged; Atropine; Cryosurgery; Dexamethasone; Erythromycin; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Methods; Middle Aged; Postoperative Complications; Prednisone; Tonometry, Ocular	1973
Gastrointestinal motor-stimulating activity of macrolide antibiotics and analysis of their side effects on the canine gut. Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:6 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Atropine; Binding, Competitive; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Motility; Leucomycins; Male; Micrococcus; Muscle Contraction; Oleandomycin	1984
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs. Gastroenterology, 1995, Volume: 109, Issue:5 Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P	1995
Migrating motor complex recorded spontaneously and induced by motilin and erythromycin in an ex vivo rabbit intestinal preparation. Peptides, 1994, Volume: 15, Issue:6 Topics: Animals; Atropine; Digestive System; Erythromycin; Esophagus; Female; Gastrointestinal Motility; In Vitro Techniques; Intestine, Small; Male; Motilin; Neostigmine; Rabbits; Stomach	1994
Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis. British journal of pharmacology, 1993, Volume: 108, Issue:1 Topics: Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Antagonists; Dogs; Electromyography; Erythromycin; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Intestine, Small; Male; Metoclopramide; Muscle Contraction; Muscle, Smooth; Serotonin Antagonists; Tropanes; Vomiting	1993
Comparison of the motor-stimulating action of EM523, an erythromycin derivative, and prostaglandin F2 alpha in conscious dogs. Japanese journal of pharmacology, 1993, Volume: 63, Issue:2 Topics: Animals; Atropine; Dinoprost; Dogs; Dopamine; Erythromycin; Fasting; Gastrointestinal Motility; Male; Motilin	1993
Motilin and erythromycin stimulate pepsinogen secretion by chief cells isolated from guinea pig stomach. Gastroenterology, 1993, Volume: 104, Issue:4 Topics: Animals; Atropine; Calcium; Carbachol; Cholecystokinin; Dinoprostone; Erythromycin; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Motilin; Pepsinogens; Secretin; Vasoactive Intestinal Peptide	1993
Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. Gastroenterology, 1993, Volume: 104, Issue:5 Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Erythromycin; Female; Gastrointestinal Motility; Immune Sera; Male; Motilin	1993
Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. Gastroenterology, 1996, Volume: 110, Issue:1 Topics: Animals; Atropine; Dogs; Erythromycin; Gastrointestinal Hormones; Motilin; Ondansetron; Pancreatic Hormones; Serotonin Antagonists; Vagotomy	1996
Effect of motilin, somatostatin and bombesin on gastroduodenal myoelectric activity in sheep. Life sciences, 1996, Volume: 58, Issue:17 Topics: Animals; Atropine; Bombesin; Duodenum; Electroencephalography; Erythromycin; Female; Gastrointestinal Motility; Hexamethonium; Motilin; Sheep; Somatostatin; Stomach	1996
Effect of motilin on gastrointestinal myoelectric activity in conscious rabbits. Peptides, 1996, Volume: 17, Issue:6 Topics: Animals; Atropine; Consciousness; Drug Interactions; Erythromycin; Gastrointestinal Agents; Hexamethonium; Motilin; Myoelectric Complex, Migrating; Ondansetron; Rabbits	1996
In vivo characterization of the colonic prokinetic effect of erythromycin in the rabbit. Pharmacology, 1997, Volume: 54, Issue:2 Topics: Animals; Anti-Bacterial Agents; Atropine; Calcium Channel Blockers; Colon; Dose-Response Relationship, Drug; Electrodes, Implanted; Erythromycin; Female; Gastrointestinal Motility; In Vitro Techniques; Male; Muscarinic Antagonists; Nifedipine; Ondansetron; Rabbits; Serotonin Antagonists; Stimulation, Chemical	1997
Acetaminophen as a marker of gastric emptying in ponies. Equine veterinary journal, 1998, Volume: 30, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Antiemetics; Area Under Curve; Atropine; Erythromycin; Gastric Emptying; Horses; Metoclopramide; Parasympatholytics; Sympatholytics; Yohimbine	1998
EM574, an erythromycin derivative, improves delayed gastric emptying of semi-solid meals in conscious dogs. European journal of pharmacology, 2000, Apr-28, Volume: 395, Issue:2 Topics: Animals; Atropine; Cisapride; Dogs; Erythromycin; Gastric Emptying; Gastrointestinal Agents; Gastroparesis; Male; Motilin; Muscarinic Antagonists; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists	2000
Enteric locus of action of prokinetics: ABT-229, motilin, and erythromycin. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:5 Topics: Animals; Atropine; Cell Size; Cells, Cultured; Dogs; Duodenum; Electric Stimulation; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Hexamethonium; In Vitro Techniques; Infusions, Intra-Arterial; Intestinal Mucosa; Jejunum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Rabbits; Stomach; Tetrodotoxin	2000
Erythromycin induces pyloric relaxation accompanied by a contraction of the gastric body after pylorus-preserving gastrectomy. Surgery, 2003, Volume: 133, Issue:6 Topics: Animals; Atropine; Dogs; Erythromycin; Gastrectomy; Gastric Emptying; Gastrointestinal Motility; Muscle Contraction; Pylorus; Stomach	2003
Direct inhibition of rat detrusor muscle contraction by erythromycin. Neurourology and urodynamics, 2004, Volume: 23, Issue:3 Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Atropine; Calcium Channel Blockers; Calcium Signaling; Carbachol; Central Nervous System Depressants; Erythromycin; Ethanol; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium; Rats; Rats, Wistar; Urinary Bladder	2004
In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine. Pharmacology, 2007, Volume: 79, Issue:3 Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Erythromycin; Hexamethonium; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intestine, Small; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tetrodotoxin; Tropisetron; Verapamil	2007
Physiological characteristics of gastric contractions and circadian gastric motility in the free-moving conscious house musk shrew (Suncus murinus). American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:4 Topics: Animals; Atropine; Behavior, Animal; Body Weight; Eating; Erythromycin; Fasting; Gastrointestinal Motility; Male; Monitoring, Physiologic; Motilin; Postprandial Period; Protein Synthesis Inhibitors; Shrews; Stomach	2010