Page last updated: 2024-09-05

atropine and dimenhydrinate

atropine has been researched along with dimenhydrinate in 7 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(dimenhydrinate)
Trials
(dimenhydrinate)
Recent Studies (post-2010) (dimenhydrinate)
26,7111,2591,6975159580

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)dimenhydrinate (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.634
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.037
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.461
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.57
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.316
Alpha-2A adrenergic receptorHomo sapiens (human)4.313
Cytochrome P450 2D6Homo sapiens (human)1.509
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.451
Alpha-2B adrenergic receptorHomo sapiens (human)5.457
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.447
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.037
Alpha-1D adrenergic receptorHomo sapiens (human)2.894
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.693
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.634
Histamine H1 receptorHomo sapiens (human)0.319
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.724
Sodium-dependent dopamine transporter Homo sapiens (human)2.245
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.158

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Christenson, CP; Christenson, PJ; Hardoin, RA; Henslee, JA; White, M1
McCabe, BF1
Shapley, JM; Wilson, JR1
Hill, ME; Marshall, BM; Wortzman, G1

Reviews

1 review(s) available for atropine and dimenhydrinate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for atropine and dimenhydrinate

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Colic medication and apparent life-threatening events.
    Clinical pediatrics, 1991, Volume: 30, Issue:5

    Topics: Atropine; Colic; Dimenhydrinate; Drug Combinations; Female; Gastroesophageal Reflux; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Monitoring, Physiologic; Phenobarbital; Respiration Disorders; Scopolamine

1991
Central aspects of drugs for motion sickness and vertigo.
    Advances in oto-rhino-laryngology, 1973, Volume: 20

    Topics: Animals; Atropine; Cats; Depression, Chemical; Diazepam; Dimenhydrinate; Electric Stimulation; Evoked Potentials; Eye Movements; Methods; Motion Sickness; Scopolamine; Stereotaxic Techniques; Vertigo; Vestibular Nuclei

1973
Post-anaesthetic jaundice due to glucose-6-phosphate dehydrogenase deficiency.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:3

    Topics: Adult; Anesthesia; Atropine; Dextropropoxyphene; Dimenhydrinate; Glucosephosphate Dehydrogenase Deficiency; Humans; Jaundice; Male; Meperidine; Secobarbital

1973
Clinical use of droperidol in pneumoencephalography.
    Canadian Medical Association journal, 1968, Feb-17, Volume: 98, Issue:7

    Topics: Adolescent; Adult; Aged; Atropine; Benperidol; Cerebral Ventriculography; Codeine; Dimenhydrinate; Humans; Injections, Intramuscular; Injections, Subcutaneous; Meperidine; Middle Aged; Opium; Pentobarbital; Tablets

1968