Page last updated: 2024-09-05

atropine and digoxin

atropine has been researched along with digoxin in 86 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(digoxin)
Trials
(digoxin)
Recent Studies (post-2010) (digoxin)
26,7111,2591,69711,4839581,289

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)digoxin (IC50)
STAT3, partialHomo sapiens (human)1.862
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)0.32
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)0.0055
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.19
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiaris (dog)0.5
Nuclear receptor ROR-gammaHomo sapiens (human)3.4798
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0055
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.2359

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199061 (70.93)18.7374
1990's6 (6.98)18.2507
2000's11 (12.79)29.6817
2010's8 (9.30)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Falk, RH1
Chastre, J; Rullière, R; Schmitt, H; Vial, F1
Downing, SE; Halloran, KH1
Berman, ND1
Bigger, JT; Cramer, M; Reiffel, JA1
Addarii, F; Pretolani, E; Zoli, I1
Desai, J; Hirschfeld, D; Massie, B; O'Young, J; Peters, R; Scheinman, MM1
García del Pozo, JM; López Morales, J; Morey Molina, A; Palou de Comasema, A; Tomas-Verdera Cosmelli, J1
Goldstein, RE; Grauer, L; Miller, M; Raff, MS; Tecklenberg, PL; Ware, JH1
Alakare, B; Kärki, NT; Nevasaari, K1
Gill, MA; Gourley, DR; Miscia, VF1
Gilbert, M; Margolis, JR; Miller, HC; Strauss, HC; Wallace, AG1
Craft, AW; Nicholson, A1
Grupp, G; Grupp, I; Heikkila, J; Luomanmaki, K; Pesola, MK; Ramo, MP; Schroder, T1
Caldwell, RW; Rebagay, WR1
Edvardsson, N; Hirsch, I; Olsson, SB2
Partanen, J1
Danilenko, MP; Esyrev, OV; Kim, EA1
Rabkin, SW1
Nieminen, MS; Partanen, J; Pellinen, T1
Runge, TM; Shapowal, BL1
Cook, LS; Doherty, JE; Elkins, RC1
Caldwell, RW; Nash, CB1
Watt, DA1
Berke, DK; Coltart, DJ; Friedman, JP; Goldman, RH; Harrison, DC; Nola, GT; Schweizer, E1
Karliner, JS; Mahler, F; O'Rourke, RA1
Julian, DG1
Archer, LT; Black, MR; Greenfield, LJ; Guenter, CA; Hinshaw, LB1
Stock, E1
Citrin, DL; Hillis, WS; O'Malley, K1
Ambre, J; Englebrecht, JA; Greenberg, S; Wilson, WR1
Goldberg, H; Kahn, D; Monheit, R; Parameswaran, R1
Beck, OA; Hochrein, H; Krämer, KD1
Griffin, JD; Szaro, RP; Weltman, JK1
Duke, M1
Langley, RB; Turner, AS; Wilson, DF1
Costello, JM; Shannon, FT1
Donoso, E; Friedberg, CK; Lyon, LJ1
Wharton, CF1
Franch, RH; King, SB1
Amir-Jahed, AK; Gauthier, P; Nadeau, RA; Porlier, GA1
Weaver, PC1
Gunnar, RM; Loeb, HS; Rahimtoola, SH; Rosen, KM; Sinno, MZ1
Aviado, DM; Marco, V; Park, CD1
Combs, RM1
Honey, M; Navab, F1
Bagwell, EE; Bernhoff, SA; Walton, RP1
Dirschinger, J; Rudolph, W2
Bexton, RS; Camm, AJ1
Alboni, P; Filippi, L; Masoni, A; Pirani, R; Preziosi, S; Shantha, N; Tomasi, AM1
Kaplanski, J; Martin, O; Weinhouse, E1
Gilfrich, HJ; Kasper, W; Meinertz, T; Pop, T; Treese, N1
Gillette, PC; Gumbiner, CH; Karpawich, PP; Lewis, R; Shih, JY; Zinner, A1
Hefner, LL; Lash, RE; Reeves, DN; Reeves, RC1
Garan, H; Powell, WJ; Powers, ER; Ruskin, JN1
Mendel, D1
Jogestrand, T; Sundqvist, K1
Battigelli, D; Delbello, G; Grill, V; Princi, T1
Peters, RJ; Tan, HL; Wilde, AA1
Bessman, ES; Curtis, LA; Howell, JM; Love, JN; Sachdeva, DK1
Biblo, LA; Carlson, MD; Mackall, JA; Quan, KJ; Van Hare, GF1
Berul, CI; Gehrmann, J; Kelly, RA; Li, GK; Maguire, CT; Michel, T; Rakhit, A; Wakimoto, H1
STEWART, GA; YOUNG, PA1
READ, WO; WELTY, JD1
ELLIS, CH1
BAYLISS, RI; KELLY, HG1
Fletcher, AK; Ramlakhan, SL1
Adnet, F; Baud, FJ; Bismuth, C; Borron, SW; Clemessy, JL; Guerrier, G; Lapostolle, F; Taboulet, P; Verdier, C1

Reviews

4 review(s) available for atropine and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Digitalis poisoning and the risk of associated treatment].
    La Revue du praticien, 1976, Nov-01, Volume: 26, Issue:49

    Topics: Acid-Base Imbalance; Aged; Atropine; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Heart Block; Heart Failure; Heart Ventricles; Humans; Kidney Failure, Chronic; Phenytoin; Potassium; Tachycardia

1976
The treatment of common cardiac arrhythmias.
    Journal of the American Pharmaceutical Association, 1976, Volume: 16, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Digitalis Glycosides; Digoxin; Heart Block; Heart Ventricles; Humans; Infant; Isoproterenol; Lidocaine; Phenytoin; Potassium; Procainamide; Propranolol; Quinidine; Tachycardia; Tachycardia, Paroxysmal

1976
It could have happened to Van Gogh: a case of fatal purple foxglove poisoning and review of the literature.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2007, Volume: 14, Issue:6

    Topics: Atropine; Cardiac Pacing, Artificial; Charcoal; Digitalis; Digoxin; Famous Persons; Fatal Outcome; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Plant Poisoning; Suicide

2007

Other Studies

82 other study(ies) available for atropine and digoxin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Adverse reactions to medication on a coronary care unit.
    Postgraduate medical journal, 1979, Volume: 55, Issue:654

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Coronary Care Units; Digoxin; Humans; Lidocaine; Middle Aged; Myocardial Infarction; Prospective Studies

1979
Inotropic responses to digoxin during hypoxia and autonomic blockade.
    The American journal of physiology, 1975, Volume: 229, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Atropine; Autonomic Nervous System; Blood Pressure; Cardiac Output; Digoxin; Dogs; Hypoxia; Myocardial Contraction; Practolol; Stimulation, Chemical; Tetraethylammonium Compounds

1975
The elderly patient in the coronary care unit. II. Incidence and treatment of arrhythmias.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:5

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Cardiac Pacing, Artificial; Coronary Care Units; Digoxin; Electric Countershock; Electrocardiography; Female; Humans; Lidocaine; Male; Myocardial Infarction; Ontario; Procainamide; Propranolol; Quinidine

1979
Effects of digoxin on sinus nodal function before and after vagal blockade in patients with sinus nodal dysfunction: a clue to the mechanisms of the action of digitalis on the sinus node.
    The American journal of cardiology, 1979, Volume: 43, Issue:5

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Pacing, Artificial; Digoxin; Electrocardiography; Female; Humans; Injections, Intravenous; Male; Middle Aged; Sinoatrial Block; Sinoatrial Node; Tachycardia; Vagus Nerve

1979
[The vagomimetic action of digitalis].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:9

    Topics: Atrioventricular Node; Atropine; Bundle of His; Digitalis Glycosides; Digoxin; Heart Conduction System; Humans; Vagus Nerve

1978
Clinical and electrophysiologic findings in patients with paroxysmal slowing of the sinus rate and apparent Mobitz type II atrioventricular block.
    Circulation, 1978, Volume: 58, Issue:2

    Topics: Adult; Aged; Arrhythmia, Sinus; Atropine; Cardiac Pacing, Artificial; Carotid Sinus; Digoxin; Electrocardiography; Electrophysiology; Female; Heart Block; Humans; Male; Massage; Middle Aged; Sinoatrial Node

1978
[Effects of chronic digoxin administration on the systolic intervals of a healthy young person].
    Revista espanola de cardiologia, 1977, Volume: 30, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Atropine; Digoxin; Drug Evaluation; Female; Heart; Heart Rate; Humans; Injections, Intravenous; Male; Myocardial Contraction; Stimulation, Chemical

1977
A new method for quantifying ventricular regularization during atrial fibrillation.
    Journal of electrocardiology, 1977, Volume: 10, Issue:2

    Topics: Atrial Fibrillation; Atropine; Digoxin; Electrocardiography; Humans; Models, Biological; Physical Exertion

1977
Effects of acetylcholine and atropine on the bile flow and biliary excretion of digoxin in the isolated perfused rat liver.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 295, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Bile; Bile Ducts, Intrahepatic; Biliary Tract; Digoxin; In Vitro Techniques; Liver; Male; Perfusion; Physostigmine; Rats

1976
Digitalis and the sick sinus syndrome. Clinical and electrophysiologic documentation of severe toxic effect on sinus node function.
    Circulation, 1975, Volume: 52, Issue:1

    Topics: Arrhythmia, Sinus; Atrioventricular Node; Atropine; Bradycardia; Digoxin; Electrocardiography; Heart Conduction System; Heart Failure; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Sinoatrial Node; Syndrome; Tachycardia

1975
The management of poisoning in children.
    Nursing times, 1975, Jun-19, Volume: 71, Issue:25

    Topics: Alcoholic Intoxication; Antidepressive Agents, Tricyclic; Aspirin; Atropine; Child; Digoxin; Household Products; Humans; Iron; Poisoning

1975
Cardiac glycosides in the treatment of experimental overdose with calcium-blocking agents.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:5

    Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Calcium Gluconate; Depression, Chemical; Digoxin; Diltiazem; Dogs; Drug Overdose; Electrocardiography; Female; Hemodynamics; Humans; Male; Myocardium; Verapamil

1992
Effect of transient vagal cold blockade upon reflex actions of a polar and nonpolar cardiac glycoside.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: Animals; Atropine; Cold Temperature; Digitoxigenin; Digoxin; Dogs; Female; Hemodynamics; Infusions, Intravenous; Male; Nerve Block; Reflex; Sympathetic Nervous System; Vagus Nerve

1992
Effects of lidocaine, procainamide, metoprolol, digoxin and atropine on the conduction of premature ventricular beats in man.
    European heart journal, 1985, Volume: 6, Issue:1

    Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Atropine; Cardiac Complexes, Premature; Digoxin; Electric Stimulation; Electrophysiology; Humans; Lidocaine; Male; Metoprolol; Procainamide

1985
Effect of intravenous digoxin on the heart at rest and during isometric exercise: a noninvasive study in normal and autonomically blocked volunteers.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:2

    Topics: Adult; Atropine; Digoxin; Drug Interactions; Echocardiography; Electrocardiography; Female; Hemodynamics; Humans; Infusions, Intravenous; Isometric Contraction; Male; Myocardial Contraction; Propranolol; Rest

1988
[Changes in the activity and regulatory properties of Na, K-ATPase from the myocardial sarcolemma in total graded ischemia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:7

    Topics: Animals; Atropine; Carbachol; Coronary Disease; Digoxin; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Rats; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Time Factors

1987
The interrelationship of morphine and the parasympathetic nervous system in digoxin-induced arrhythmias in the guinea-pig.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Digoxin; Dose-Response Relationship, Drug; Guinea Pigs; Male; Morphine; Parasympathetic Nervous System; Vagotomy

1988
Intravenous digoxin blunts the rise of inotropy induced by isometric exercise: a noninvasive study in healthy volunteers.
    Annals of clinical research, 1987, Volume: 19, Issue:6

    Topics: Adult; Atropine; Autonomic Nerve Block; Digoxin; Echocardiography; Female; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Isometric Contraction; Male; Muscle Contraction; Propranolol

1987
Difference in degree of A-V block and QS2 abbreviation of ouabain digoxin and digitoxin in cats.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 280, Issue:2

    Topics: Animals; Atropine; Cats; Diet; Digitoxin; Digoxin; Electrocardiography; Female; Heart Block; Heart Rate; Male; Ouabain; Time Factors

1986
Cardiovascular effects of atropine in postoperative cardiac patients receiving digoxin for ventricular dysfunction.
    American heart journal, 1986, Volume: 111, Issue:1

    Topics: Atropine; Cardiac Output; Cardiovascular System; Digoxin; Heart Diseases; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Postoperative Care

1986
Effect of an aminocardenolide and digoxin upon atrioventricular refractory period in the dog.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Animals; Atrioventricular Node; Atropine; Digitoxigenin; Digoxin; Dogs; Female; Heart Conduction System; Male; Metoprolol; Neural Conduction; Pressoreceptors; Refractory Period, Electrophysiological; Sympathectomy

1985
Sensitivity to propranolol after digoxin intoxication.
    British medical journal, 1968, Aug-17, Volume: 3, Issue:5615

    Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Cardiac Complexes, Premature; Digoxin; Drug Hypersensitivity; Dyspnea; Heart Rate; Humans; Male; Middle Aged; Propranolol; Tachycardia; Uremia

1968
The inotropic effects of digoxin in hyperkalemia. Relation to (Na+,K+)-ATPase inhibition in the intact animal.
    Circulation, 1973, Volume: 48, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Atropine; Digoxin; Dogs; Heart; Heart Rate; Heart Ventricles; Hyperkalemia; Microsomes; Myocardium; Potassium; Practolol; Sodium

1973
Effects of chronic digoxin administration on left ventricular performance in the normal conscious dog.
    Circulation, 1974, Volume: 50, Issue:4

    Topics: Animals; Atropine; Blood Pressure; Cardiac Catheterization; Digoxin; Dogs; Electrocardiography; Heart Atria; Heart Rate; Heart Ventricles; Injections, Intramuscular; Manometry; Pacemaker, Artificial; Phenylephrine; Propranolol; Stimulation, Chemical; Transducers; Ultrasonics; Ventricular Function

1974
The problems of treating disturbances of heart rhythm at home.
    Therapeutische Umschau. Revue therapeutique, 1974, Volume: 31, Issue:2

    Topics: Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Digoxin; Home Nursing; Humans; Lidocaine; Myocardial Infarction; Ouabain; Practolol; Procainamide; Quinidine; Valsalva Maneuver

1974
Prevention and reversal of myocardial failure in endotoxin shock.
    Surgery, gynecology & obstetrics, 1973, Volume: 136, Issue:1

    Topics: Animals; Atropine; Blood Pressure; Carbon Dioxide; Cardiac Output; Coronary Circulation; Digoxin; Disease Models, Animal; Dogs; Escherichia coli; Heart Failure; Heart Rate; Myocardial Infarction; Myocardium; Oxygen Consumption; Shock, Septic; Vascular Resistance

1973
Prophylactic total coronary care.
    American heart journal, 1973, Volume: 85, Issue:6

    Topics: Arrhythmias, Cardiac; Atropine; Diet Therapy; Digoxin; Electrocardiography; Female; Furosemide; Heart Block; Heart Failure; Heparin; Hospitalization; Humans; Hypotension; Male; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Oxygen Inhalation Therapy; Progressive Patient Care; Shock, Cardiogenic

1973
Cardiac standstill due to digoxin poisoning successfully treated with atrial pacing.
    British medical journal, 1973, Jun-02, Volume: 2, Issue:5865

    Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digoxin; Electrocardiography; Heart Arrest; Heart Atria; Heart Block; Heart Conduction System; Humans; Hyperkalemia; Male; Middle Aged; Pacemaker, Artificial; Time Factors

1973
Interaction of pentobarbital anesthesia with digoxin-mediated bradycardia.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Anesthesia, Intravenous; Animals; Atropine; Blood Pressure; Bradycardia; Chloralose; Digoxin; Dogs; Drug Interactions; Electrocardiography; Heart Rate; Pentobarbital; Time Factors; Urethane; Vagotomy; Vagus Nerve

1973
Sinus bradycardia due to lidocaine: clinical-electrophysiologic correlations.
    Journal of electrocardiology, 1974, Volume: 7, Issue:1

    Topics: Aged; Animals; Atropine; Bradycardia; Coronary Disease; Digoxin; Female; Heart Block; Heart Failure; Humans; Injections, Intravenous; Lidocaine; Male; Myocardial Infarction; Rabbits

1974
[Suicidal digoxin intoxication with hyperkalaemia: report of a case (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Apr-12, Volume: 99, Issue:15

    Topics: Acute Disease; Adult; Atropine; Bradycardia; Digoxin; Electrocardiography; Female; Furosemide; Humans; Hyperkalemia; Intensive Care Units; Pacemaker, Artificial; Poisoning; Radioimmunoassay; Suicide

1974
Ouabain antagonism of smooth muscle contraction.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Bradykinin; Calcium; Digoxin; Drug Antagonism; Drug Interactions; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Serotonin; Sodium; Time Factors

1972
Atrioventricular block due to accidental digoxin ingestion treated with atropine.
    American journal of diseases of children (1960), 1972, Volume: 124, Issue:5

    Topics: Accidents, Home; Atropine; Digoxin; Electrocardiography; Heart Block; Humans; Infant; Isoproterenol; Male

1972
Acute coronary care: a year's experience at Napier Hospital.
    The New Zealand medical journal, 1968, Volume: 67, Issue:431

    Topics: Anticoagulants; Arrhythmias, Cardiac; Atropine; Digoxin; Electric Countershock; Heart Arrest; Humans; Intensive Care Units; Isoproterenol; Levallorphan; Lidocaine; Medical Staff, Hospital; Meperidine; Myocardial Infarction; New Zealand; Nursing Service, Hospital; Oxygen Inhalation Therapy; Procainamide; Quinidine; Sympathomimetics; Ventricular Fibrillation

1968
Drugs and children.
    The New Zealand medical journal, 1968, Volume: 67, Issue:430

    Topics: Aminophylline; Aspirin; Atropine; Cardiomyopathies; Cataract; Child, Preschool; Chloramphenicol; Chlorothiazide; Conjunctivitis; Digoxin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Iatrogenic Disease; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Ophthalmic Solutions; Pre-Eclampsia; Pregnancy; Purpura, Thrombocytopenic; Substance-Related Disorders; Suppositories

1968
Suppression of refractory recurrent ventricular tachycardia by transvenous rapid cardiac pacing and antiarrhythmic drugs. Report of seven cases.
    American heart journal, 1970, Volume: 79, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atropine; Digitalis Glycosides; Digoxin; Electrocardiography; Female; Heart Ventricles; Humans; Isoproterenol; Lidocaine; Male; Middle Aged; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia; Ventricular Fibrillation

1970
Attempted suicide by digoxin self administration and its management.
    Guy's Hospital reports, 1970, Volume: 119, Issue:3

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Digoxin; Electrocardiography; Female; Humans; Male; Pacemaker, Artificial; Poisoning; Potassium Chloride; Propranolol; Suicide

1970
Atrial fibrillation. II.
    British medical journal, 1971, Jul-31, Volume: 3, Issue:5769

    Topics: Atrial Fibrillation; Atropine; Digoxin; Electric Countershock; Humans; Male; Middle Aged; Mitral Valve Stenosis; Myocardial Infarction; Ouabain; Warfarin

1971
Production of increased right-to-left shunting by rapid heart rates in patients with tetralogy of Fallot.
    Circulation, 1971, Volume: 44, Issue:2

    Topics: Atropine; Blood Pressure; Cardiac Catheterization; Cardiac Volume; Child, Preschool; Cyanosis; Digoxin; Female; Heart Rate; Humans; Infant; Oxygen; Pacemaker, Artificial; Propranolol; Pulmonary Circulation; Respiration; Tachycardia, Paroxysmal; Tetralogy of Fallot

1971
Effects of cardiac glycosides injected into the atrioventricular node artery of the dog.
    Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Cardanolides; Cardiac Glycosides; Digoxin; Dogs; Electric Stimulation; Heart Conduction System; Heart Rate; Injections, Intra-Arterial; Lanatosides; Stellate Ganglion; Vagus Nerve

1971
A study of the cardiovascular effects of halothane.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 49, Issue:2

    Topics: Animals; Arteries; Atropine; Blood Flow Velocity; Blood Pressure; Calcium Chloride; Carbon Dioxide; Cardiac Output; Cardiac Volume; Cardiovascular System; Coronary Vessels; Digoxin; Dogs; Electrocardiography; Epinephrine; Halothane; Heart Auscultation; Heart Rate; Hematocrit; Hemoglobins; Hemorrhage; Injections, Intravenous; Isoproterenol; Oxygen Consumption; Propranolol; Radioisotopes; Vagotomy; Xenon

1971
Cardiac conduction in patients with symptomatic sinus node disease.
    Circulation, 1971, Volume: 43, Issue:6

    Topics: Aged; Arrhythmia, Sinus; Atropine; Bundle-Branch Block; Digoxin; Electrocardiography; Female; Heart Block; Heart Conduction System; Heart Rate; Humans; Male; Methyldopa; Middle Aged; Pacemaker, Artificial; Sinoatrial Node

1971
Bronchopulmonary effects of digitalis in the anesthetized dog.
    Diseases of the chest, 1968, Volume: 54, Issue:5

    Topics: Animals; Atropine; Blood Pressure; Bronchi; Digoxin; Dogs; Extracorporeal Circulation; Lung; Lung Compliance; Muscle, Smooth; Pulmonary Circulation; Respiratory Function Tests; Strophanthins; Vascular Resistance

1968
Unusual response to reserpine in paroxysmal atrial tachycardia with block unassociated with digitalis.
    Southern medical journal, 1967, Volume: 60, Issue:8

    Topics: Atropine; Digoxin; Electrocardiography; Female; Heart Block; Heart Rate; Humans; Reserpine; Tachycardia, Paroxysmal

1967
Self-poisoning with digoxin: successful treatment with atropine.
    British medical journal, 1967, Sep-09, Volume: 3, Issue:5566

    Topics: Anuria; Atropine; Digoxin; Electrocardiography; Female; Humans; Injections, Intravenous; Liver Function Tests; Middle Aged

1967
Correlation of cardiac plethysmography with other circulatory recordings during the action of anesthetics and cardiac stimulants.
    Acta anaesthesiologica Scandinavica, 1967, Volume: 11, Issue:3

    Topics: Anesthetics; Animals; Atropine; Blood Circulation; Blood Pressure; Blood Volume; Digoxin; Dogs; Epinephrine; Heart; Heart Rate; Isoproterenol; Lidocaine; Methohexital; Norepinephrine; Parasympathomimetics; Pentobarbital; Pilocarpine; Plethysmography; Sympathomimetics

1967
[Standard therapy of acute myocardial infarction.--II: Management of arrhythmias].
    Herz, 1981, Volume: 6, Issue:1

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Complexes, Premature; Digoxin; Heart Block; Heart Failure; Humans; Lidocaine; Myocardial Infarction; Propranolol; Tachycardia

1981
Cardiac transplantation--the ideal model for electrophysiologic drug testing?
    International journal of cardiology, 1983, Volume: 4, Issue:3

    Topics: Animals; Atropine; Cardiovascular Agents; Digoxin; Disopyramide; Edrophonium; Electrophysiology; Heart; Heart Conduction System; Heart Rate; Heart Transplantation; Humans; Norepinephrine; Quinidine

1983
Acute effects of lignocaine, procainamide, metoprolol, digoxin and atropine on human myocardial refractoriness.
    Cardiovascular research, 1984, Volume: 18, Issue:8

    Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Atropine; Digoxin; Heart; Heart Rate; Heart Ventricles; Humans; Lidocaine; Male; Metoprolol; Procainamide; Time Factors; Ventricular Function

1984
Clinical effects of digoxin on sinus node and atrioventricular node function after pharmacologic autonomic blockade.
    American heart journal, 1984, Volume: 108, Issue:5

    Topics: Adult; Aged; Atrioventricular Node; Atropine; Autonomic Nervous System; Digitalis Glycosides; Digoxin; Electrophysiology; Female; Heart Conduction System; Humans; Male; Middle Aged; Propranolol; Sinoatrial Node

1984
Modification of digoxin induced arrhythmogenicity in adult rats following atropine administration.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 39, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Digoxin; Drug Interactions; Electrocardiography; Female; Rats

1983
Influence of digoxin on sinus node function after pharmacologic autonomic blockade.
    Klinische Wochenschrift, 1983, May-16, Volume: 61, Issue:10

    Topics: Adult; Aged; Atropine; Digoxin; Female; Humans; Male; Middle Aged; Propranolol; Sinoatrial Node

1983
Comparative electrophysiologic effects of digoxin in the nonsedated chronically instrumented puppy.
    American heart journal, 1982, Volume: 103, Issue:6

    Topics: Aging; Anesthesia; Animals; Atropine; Cardiac Pacing, Artificial; Digoxin; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Heart Rate; Sinoatrial Node

1982
Mechanism of additive effects of digoxin and quinidine on contractility in isolated cardiac muscle.
    The American journal of cardiology, 1982, Volume: 50, Issue:3

    Topics: Animals; Atropine; Digoxin; Drug Interactions; Female; Ferrets; Male; Myocardial Contraction; Papillary Muscles; Quinidine

1982
[Standard therapy of acute myocardial infarction.--II. Management of hemodynamic complications. (author's transl)].
    Herz, 1981, Volume: 6, Issue:1

    Topics: Analgesics; Atropine; Digoxin; Dobutamine; Dopamine; Drug Therapy, Combination; Heart Failure; Heart Rupture; Hemodynamics; Humans; Hypertension; Hypotension; Myocardial Infarction; Propranolol; Shock, Cardiogenic; Vasodilator Agents

1981
Neural effect of digitalis glycosides on gracilis vascular resistance in hypotension.
    The American journal of physiology, 1980, Volume: 238, Issue:5

    Topics: Animals; Atropine; Blood Pressure; Digoxin; Dogs; Female; Hypotension; Male; Muscles; Phenoxybenzamine; Strophanthidin; Vascular Resistance

1980
A basis for the pharmacology of hearing.
    The Journal of laryngology and otology, 1980, Volume: 94, Issue:12

    Topics: Acetylcholine; Action Potentials; Animals; Atropine; Brain; Calcium; Cochlea; Digoxin; Efferent Pathways; Guinea Pigs; Hearing; Humans; Physostigmine; Verapamil

1980
Effect of autonomic blockade on digoxin-induced ECG changes at rest and during exercise in healthy subjects.
    Journal of electrocardiology, 1993, Volume: 26, Issue:3

    Topics: Adult; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Digoxin; Electrocardiography; Exercise Test; Humans; Male; Propranolol

1993
Role of the parasympathetic autonomic nervous system in digitalis intoxication: electrocardiographic and histological study.
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 1996, Volume: 50, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Digoxin; Electrocardiography; Heart; Myocardium; Parasympathetic Nervous System; Parasympatholytics; Poisoning; Rabbits

1996
Suppression of torsades de pointes by atropine.
    Heart (British Cardiac Society), 1998, Volume: 79, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Atropine; Digoxin; Electrocardiography; Female; Humans; Torsades de Pointes

1998
A potential role for glucagon in the treatment of drug-induced symptomatic bradycardia.
    Chest, 1998, Volume: 114, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atropine; Blood Pressure; Bradycardia; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Female; Glucagon; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Time Factors; Treatment Outcome

1998
Endocardial stimulation of efferent parasympathetic nerves to the atrioventricular node in humans: optimal stimulation sites and the effects of digoxin.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2001, Volume: 5, Issue:2

    Topics: Aged; Anti-Arrhythmia Agents; Atrioventricular Node; Atropine; Digoxin; Drug Tolerance; Electrocardiography; Endocardium; Female; Heart Atria; Humans; Male; Middle Aged; Neurons, Efferent; Parasympathetic Nervous System; Stimulation, Chemical

2001
In vivo electrophysiologic studies in endothelial nitric oxide synthase (eNOS)-deficient mice.
    Journal of cardiovascular electrophysiology, 2001, Volume: 12, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Digoxin; Disease Models, Animal; Disease Susceptibility; Electrocardiography; Electrophysiologic Techniques, Cardiac; Endothelium, Vascular; Enzyme Inhibitors; Female; Genotype; Heart Conduction System; Heart Rate; Male; Mice; Models, Cardiovascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Observer Variation; Parasympatholytics; Propranolol; Sympatholytics

2001
STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Arsphenamine; Atropine; Biological Assay; Biometry; Cocaine; Digoxin; Epinephrine; Ergonovine; Ergot Alkaloids; Hexamethonium Compounds; Histamine; Insulin; Meperidine; Methadone; Morphine; Pharmacology; Promethazine; Research; Riboflavin; Statistics as Topic; Strophanthins; Toxicology; Tubocurarine

1963
STUDIES ON SOME CARDIAC EFFECT OF TAURINE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Acetylcholine; Atropine; Digoxin; Dogs; Epinephrine; Heart; Metabolism; Myocardium; Pharmacology; Potassium; Procainamide; Quinidine; Research; Taurine

1964
CONTROL OF VENTRICULAR TACHYCARDIAS IN DOGS BY B.W. 62-235, A DERIVATIVE OF METHOXAMINE.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jul-01, Volume: 150

    Topics: Anti-Arrhythmia Agents; Atropine; Blood Pressure; Blood Pressure Determination; Digoxin; Dogs; Epinephrine; Hydrocarbons; Methoxamine; Ouabain; Pharmacology; Quinidine; Research; Tachycardia; Tachycardia, Ventricular

1964
Influence of heart-rate on cardiac output; studies with digoxin and atropine.
    Lancet (London, England), 1949, Dec-10, Volume: 2, Issue:6589

    Topics: Atropine; Cardiac Output; Digitalis; Digitalis Glycosides; Digoxin; Heart; Heart Rate; Humans

1949
Digoxin-specific Fab fragments as single first-line therapy in digitalis poisoning.
    Critical care medicine, 2008, Volume: 36, Issue:11

    Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Atropine; Cardiotonic Agents; Critical Care; Digitalis Glycosides; Digitoxin; Digoxin; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Poisoning; Retrospective Studies

2008