Page last updated: 2024-09-05

atropine and diazoxide

atropine has been researched along with diazoxide in 30 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(diazoxide)
Trials
(diazoxide)
Recent Studies (post-2010) (diazoxide)
26,7111,2591,6972,92386445

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199011 (36.67)18.7374
1990's2 (6.67)18.2507
2000's9 (30.00)29.6817
2010's8 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Man in 't Veld, AJ; Schalekamp, MA; Verhoeven, RP; Wenting, GJ1
Siegel, IA; Watson, EL; Williams, JA1
Graham, RM; Oates, HF; Stoker, LM; Stokes, GS1
Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE1
Loubatières, A; Loubatières-Mariani, MM1
Constantine, JW; McShane, WK; Wang, SC1
De la Tour, J; Debray, C; Roze, C; Souchard, M; Vaille, C1
Biggs, DF; Peterson, MA1
Biggs, DF1
Kuhar, MJ; Lepor, H1
Gilon, P; Henquin, JC; Nenquin, M1
Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A1
Benoit, JN; Cohen, MV; Downey, JM; Oldenburg, O; Qin, Q; Sharma, AR1
Djahanguiri, B; Jafari, MR; Shafaghi, B; Zarrindast, MR1
Philbrick, W; Yamazaki, H; Zawalich, KC; Zawalich, WS1
Barreto, SG; Carati, CJ; Jaya, SR; Saccone, GT; Schloithe, AC; Toouli, J; Woods, CM1
Barreto, SG; Carati, CJ; Saccone, GT; Schloithe, AC; Toouli, J1

Reviews

1 review(s) available for atropine and diazoxide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

29 other study(ies) available for atropine and diazoxide

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Sympathetic and parasympathetic components of reflex cardiostimulation during vasodilator treatment of hypertension.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adrenergic beta-Antagonists; Atropine; Blood Pressure; Diazoxide; Drug Interactions; Hemodynamics; Humans; Hypertension

1978
Calcium mediation of cholinergic-stimulated amylase release from mouse parotid gland.
    The American journal of physiology, 1979, Volume: 236, Issue:5

    Topics: Amylases; Animals; Atropine; Biological Transport, Active; Calcimycin; Calcium; Carbachol; Diazoxide; Dose-Response Relationship, Drug; Isoproterenol; Male; Mice; Parotid Gland; Phenytoin

1979
Haemodynamic effects of prazosin.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 224, Issue:2

    Topics: Animals; Atropine; Blood Cell Count; Blood Pressure; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hemodynamics; Isoproterenol; Pentolinium Tartrate; Prazosin; Quinazolines; Rats; Renin; Timolol

1976
An effect of hyposmolarity on insulin release in vitro.
    The American journal of physiology, 1975, Volume: 228, Issue:3

    Topics: Amiloride; Amylases; Animals; Atropine; Calcium; Choline; Colchicine; Diazoxide; Epinephrine; Glucagon; Glucose; Hypotonic Solutions; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Male; Osmolar Concentration; Ouabain; Pancreas; Phentolamine; Phenytoin; Propranolol; Rats; Sorbitol; Tolbutamide; Trypsin Inhibitors; Vinblastine

1975
In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas.
    Endocrinologia experimentalis, 1974, Volume: 8, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Diazoxide; Epinephrine; Glucagon; Glucose; Glyburide; Heptoses; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Ketoses; Norepinephrine; Pancreas; Parasympathomimetics; Perfusion; Phenoxybenzamine; Practolol; Propranolol; Sulfonylurea Compounds; Theophylline; Tolbutamide

1974
Comparison of carotid artery occlusion and tilt responses in dogs.
    The American journal of physiology, 1971, Volume: 221, Issue:6

    Topics: Animals; Atropine; Blood Pressure; Cardiac Output; Carotid Arteries; Constriction; Diazoxide; Dogs; Female; Heart Rate; Hexamethonium Compounds; Hypotension, Orthostatic; Male; Nitrites; Posture; Vagotomy

1971
[Insulin: accelerator of choleresis and external pancreas secretion in the rat].
    Annales pharmaceutiques francaises, 1969, Volume: 27, Issue:5

    Topics: Amylases; Animals; Atropine; Bile; Diazoxide

1969
The effects of diazoxide on total lung resistance in the anesthetized paralyzed guinea-pig.
    Agents and actions, 1980, Volume: 10, Issue:3

    Topics: Airway Resistance; Animals; Atropine; Cromolyn Sodium; Diazoxide; Dose-Response Relationship, Drug; Female; Glossopharyngeal Nerve; Guinea Pigs; Histamine Release; Indomethacin; Lung Compliance; Male; Propranolol; Pyrilamine; Receptors, Adrenergic; Receptors, Nicotinic; Vagotomy

1980
Direct and indirect actions of histamine on airway smooth muscle in guinea pigs.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:6

    Topics: Airway Resistance; Animals; Aspirin; Atropine; Carotid Sinus; Cromolyn Sodium; Diazoxide; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Muscle, Smooth; Pyrilamine; Serotonin; Tartrazine; Vagotomy

1984
Characterization of muscarinic cholinergic receptor binding in the vas deferens, bladder, prostate and penis of the rabbit.
    The Journal of urology, 1984, Volume: 132, Issue:2

    Topics: Animals; Atropine; Binding, Competitive; Diazoxide; Haloperidol; In Vitro Techniques; Male; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Penis; Phentolamine; Propranolol; Prostate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Urinary Bladder; Vas Deferens

1984
Muscarinic stimulation exerts both stimulatory and inhibitory effects on the concentration of cytoplasmic Ca2+ in the electrically excitable pancreatic B-cell.
    The Biochemical journal, 1995, Oct-01, Volume: 311 ( Pt 1)

    Topics: Acetylcholine; Action Potentials; Animals; Atropine; Calcium; Calcium Channel Blockers; Cytoplasm; Diazoxide; Electric Stimulation; Female; Gallopamil; Islets of Langerhans; Mice; Potassium; Receptors, Muscarinic; Sodium; Terpenes; Thapsigargin

1995
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
    Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1

    Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil

1997
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
    Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3

    Topics: Acetylcholine; Analysis of Variance; Androstadienes; Animals; Aorta; Atropine; Cell Line; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Female; Free Radical Scavengers; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Hydroxy Acids; Ionophores; Ischemic Preconditioning; Male; Methacholine Chloride; Microscopy, Fluorescence; Muscarinic Agonists; Muscle, Smooth, Vascular; Perfusion; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Potassium Channel Blockers; Potassium Channels; Protein-Tyrosine Kinases; Rabbits; Rats; Reactive Oxygen Species; Receptors, Cholinergic; Signal Transduction; Tiopronin; Valinomycin; Wortmannin

2002
Influence of potassium channel modulators on morphine state-dependent memory of passive avoidance.
    Behavioural pharmacology, 2004, Volume: 15, Issue:2

    Topics: Adenosine Triphosphate; Animals; Atropine; Avoidance Learning; Diazoxide; Glyburide; Male; Memory; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Potassium Channel Blockers; Potassium Channels

2004
Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:1

    Topics: Animals; Atropine; Carbachol; Colforsin; Diazoxide; Enzyme Activation; Glucose; Hyperglycemia; In Vitro Techniques; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Sprague-Dawley; Type C Phospholipases

2006
Galanin inhibits caerulein-stimulated pancreatic amylase secretion via cholinergic nerves and insulin.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:2

    Topics: Amylases; Animals; Atropine; Carbachol; Ceruletide; Cholinergic Agonists; Cholinergic Fibers; Diazoxide; Dose-Response Relationship, Drug; Galanin; Glucose; Hexamethonium; In Vitro Techniques; Insulin; Mice; Muscarinic Antagonists; Pancreas; Paracrine Communication; Receptor, Galanin, Type 2; Tetrodotoxin

2009
Galanin potentiates supramaximal caerulein-stimulated pancreatic amylase secretion via its action on somatostatin secretion.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:6

    Topics: Amylases; Animals; Atropine; Ceruletide; Diazoxide; Dose-Response Relationship, Drug; Galanin; Insulin; Mice; Muscarinic Antagonists; Octreotide; Pancreas; Receptors, Galanin; Receptors, Somatostatin; Somatostatin; Substance P; Tetrodotoxin

2009