atropine has been researched along with dexetimide in 19 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (dexetimide) | Trials (dexetimide) | Recent Studies (post-2010) (dexetimide) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 117 | 4 | 4 |
| Protein | Taxonomy | atropine (IC50) | dexetimide (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Mus musculus (house mouse) | 0.0033 | |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | 0.0033 | |
| Muscarinic acetylcholine receptor M5 | Mus musculus (house mouse) | 0.0033 | |
| Muscarinic acetylcholine receptor M3 | Mus musculus (house mouse) | 0.0033 | |
| Muscarinic acetylcholine receptor M2 | Mus musculus (house mouse) | 0.0033 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovacs, I; Roeske, WR; Varga, EV; Waite, SL; Yamamura, HI | 1 |
| Bertram, U; Kasten, A; Lüllmann, H; Ziegler, A | 1 |
| Binenfeld, Z; Deljac, V; Fajdetić, A; Wilhelm, K | 1 |
| Gianutsos, G; Lal, H | 1 |
| Carson, S; Godwin, S; Kato, G; Massoulié, J | 1 |
| Gianutsos, G; Hynes, MD; Lal, H | 1 |
| Bottlaender, M; Brouillet, E; Cayla, J; Chavoix, C; Crouzel, C; Mazière, B; Mazière, M; Prenant, C; Stulzaft, O; Varastet, M | 1 |
| Dannals, RF; Matsumura, K; Scheffel, U; Uno, Y; Wagner, HN; Wilson, AA | 1 |
| Dannals, RF; Ravert, HT; Scheffel, UA; Stathis, M; Wagner, HN; Wilson, AA | 1 |
| Delhaye, M; Larose, L; Longnecker, DS; Morisset, J; Poirier, GG; Swillens, S; Taton, G | 1 |
| Domino, EF; Head, R; Pohorecki, R | 1 |
| Gorissen, H; Laduron, PM; Leysen, JE | 1 |
| Cepeda, C; Collard, P; Comar, D; Godot, JM; Mazière, M; Naquet, R | 1 |
| Lüllmann, H; Schmaus, H; Staemmler, C; Ziegler, A | 1 |
| Dorff, RJ; Gaginella, TS; O'Dorisio, TM; Rimele, TJ | 1 |
| Dannals, RF; Guilarte, TR; Lever, JR; Müller-Gärtner, HW; Ravert, HT; Sasaki, M; Wagner, HN | 1 |
| Bosman, IJ; de Zeeuw, RA; Ensing, K | 1 |
| Fixmann, A; Holschbach, M; Müller-Gärtner, HW; Weckesser, M | 1 |
| Christopoulos, A; Lanzafame, A; Mitchelson, F | 1 |
19 other study(ies) available for atropine and dexetimide
| Article | Year |
|---|---|
Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line.
Topics: Amino Acid Sequence; Animals; Carbachol; Cloning, Molecular; Cyclic AMP; Humans; Mice; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Muscarinic; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Species Specificity | 1998 |
Improved treatment of organophosphate intoxication by use of scopolamine or dexetimide.
Topics: Animals; Atropine; Dexetimide; Drug Therapy, Combination; Isoflurophate; Mice; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Piperidines; Rabbits; Scopolamine | 1977 |
Protective effect of dexetimide and HI-6 in poisoning with highly toxic organophosphorus compounds.
Topics: Animals; Antidotes; Atropine; Dexetimide; Male; Mice; Organophosphate Poisoning; Piperidines; Pyridinium Compounds; Rats | 1979 |
Modification of apomorphine induced aggression by changing central cholinergic activity in rats.
Topics: Aggression; Animals; Apomorphine; Atropine; Dexetimide; Humans; Iodides; Male; Parasympathetic Nervous System; Pilocarpine; Rats; Vocalization, Animal | 1977 |
Biochemical studies on muscarinic receptors.
Topics: Acetylcholine; Alkylating Agents; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Cattle; Choline; Dexetimide; Kinetics; Ligands; Muscle Contraction; Muscle, Smooth; Quinuclidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Solubility; Subcellular Fractions | 1977 |
Effects of cholinergic agonists and antagonists on morphine-withdrawal syndrome.
Topics: Animals; Atropine; Dexetimide; Humans; Male; Morphine Dependence; Pilocarpine; Rats; Scopolamine Derivatives; Substance Withdrawal Syndrome | 1976 |
In vivo visualization of central muscarinic receptors using [11C]quinuclidinyl benzilate and positron emission tomography in baboons.
Topics: Animals; Atropine; Cerebral Cortex; Dexetimide; Electroencephalography; Male; Papio; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Tomography, Emission-Computed | 1992 |
Effects of atropine treatment on in vitro and in vivo binding of 4-[125I]-dexetimide to central and myocardial muscarinic receptors.
Topics: Animals; Atropine; Central Nervous System; Dexetimide; In Vitro Techniques; Iodine Radioisotopes; Male; Myocardium; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Up-Regulation | 1991 |
In vivo biodistribution of two [18F]-labelled muscarinic cholinergic receptor ligands: 2-[18F]- and 4-[18F]-fluorodexetimide.
Topics: Animals; Atropine; Cerebellum; Cerebral Cortex; Corpus Striatum; Dexetimide; Male; Mice; Mice, Inbred Strains; Receptors, Muscarinic; Tomography, Emission-Computed | 1991 |
Muscarinic cholinergic receptors in pancreatic acinar carcinoma of rat.
Topics: Adenocarcinoma; Amylases; Animals; Atropine; Binding, Competitive; Carbachol; Carcinoma; Dexetimide; DNA; Kinetics; Pancreatic Neoplasms; Proteins; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Stereoisomerism | 1985 |
Effects of selected muscarinic cholinergic antagonists on [3H]acetylcholine release from rat hippocampal slices.
Topics: Acetylcholine; Animals; Atropine; Atropine Derivatives; Benactyzine; Carbachol; Dexetimide; Dose-Response Relationship, Drug; Electric Stimulation; Hemicholinium 3; Hippocampus; Male; Nicotine; Phenylpropionates; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Muscarinic receptor: multiple sites or unitary concept?
Topics: Animals; Atropine; Benzodiazepinones; Brain; Dexetimide; Dogs; Gastric Mucosa; In Vitro Techniques; Microsomes; Piperazines; Piperidines; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic | 1981 |
In vivo characterization of myocardium muscarinic receptors by positron emission tomography.
Topics: Animals; Atropine; Carbon Radioisotopes; Dexetimide; Dose-Response Relationship, Drug; Heart; Heart Rate; Liver; Male; Myocardium; Papio; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Tomography, Emission-Computed | 1981 |
Comparison of atropine and dexetimide in treatment of intoxications by selected organophosphates.
Topics: Animals; Atropine; Dexetimide; Diet; Guinea Pigs; Insecticides; Isoflurophate; Lethal Dose 50; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Piperidines | 1982 |
Pharmacologic identification of muscarinic receptors in the pylorus of the cat by binding of [3H]-quinuclidinyl benzilate.
Topics: Animals; Atropine; Bethanechol Compounds; Cats; Dexetimide; Female; Kinetics; Male; Propantheline; Pylorus; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Stereoisomerism; Tropicamide | 1980 |
Assessment of brain muscarinic acetylcholinergic receptors in living mice using a simple probe, [125I]-4-iododexetimide and [125I]-4-iodolevetimide.
Topics: Animals; Atropine; Binding, Competitive; Brain; Dexetimide; Iodine Radioisotopes; Kinetics; Male; Mice; Mice, Inbred Strains; Radioligand Assay; Receptors, Muscarinic; Time Factors | 1993 |
Unusual reduction of the in vitro skin permeation of [3H]dexetimide by atropine.
Topics: Adjuvants, Anesthesia; Administration, Cutaneous; Animals; Antiparkinson Agents; Atropine; Cell Membrane Permeability; Deuterium; Dexetimide; Drug Interactions; Membranes; Radiopharmaceuticals; Skin; Swine | 1998 |
Influence of acetylcholine on binding of 4-[125I]iododexetimide to muscarinic brain receptors.
Topics: Acetylcholine; Animals; Atropine; Binding Sites; Brain; Dexetimide; In Vitro Techniques; Iodine Radioisotopes; Receptors, Muscarinic; Swine; Synaptosomes; Tomography, Emission-Computed, Single-Photon | 1998 |
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria.
Topics: Acetylcholine; Allosteric Regulation; Animals; Atropine; Carbachol; Cardiotonic Agents; Dexetimide; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Phthalimides; Pirenzepine; Quaternary Ammonium Compounds; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |