Page last updated: 2024-09-05

atropine and desipramine

atropine has been researched along with desipramine in 104 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (desipramine)	Trials (desipramine)	Recent Studies (post-2010) (desipramine)
26,711	1,259	1,697	5,775	487	414

Protein Interaction Comparison

Protein	Taxonomy	desipramine (IC50)
Solute carrier family 22 member 1	Homo sapiens (human)	9.18
5-hydroxytryptamine receptor 2C	Rattus norvegicus (Norway rat)	0.35
Alpha-2A adrenergic receptor	Homo sapiens (human)	0.0003
5-hydroxytryptamine receptor 2A	Rattus norvegicus (Norway rat)	0.35
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.0034
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.0003
Alpha-2C adrenergic receptor	Homo sapiens (human)	0.0003
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.35
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	0.0031
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	7.8
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 1D	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 1F	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 2B	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 6	Rattus norvegicus (Norway rat)	0.35
Histamine H1 receptor	Rattus norvegicus (Norway rat)	0.0008
Sodium-dependent serotonin transporter	Homo sapiens (human)	0.1961
5-hydroxytryptamine receptor 7	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 5A	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 5B	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 3A	Rattus norvegicus (Norway rat)	0.35
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.0003
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	3.8
Sodium-dependent dopamine transporter	Homo sapiens (human)	9.9
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	1.4035
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	1.52
5-hydroxytryptamine receptor 4	Rattus norvegicus (Norway rat)	0.35
5-hydroxytryptamine receptor 3B	Rattus norvegicus (Norway rat)	0.35
Solute carrier family 22 member 2	Rattus norvegicus (Norway rat)	10
Transporter	Rattus norvegicus (Norway rat)	7.8

Research

Studies (104)

Timeframe	Studies, this research(%)	All Research%
pre-1990	67 (64.42)	18.7374
1990's	12 (11.54)	18.2507
2000's	15 (14.42)	29.6817
2010's	10 (9.62)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP	1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Andrews, PR; Craik, DJ; Martin, JL	1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM	1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Chiba, S	4
Richelson, E	1
Ueki, S; Yamamoto, T	1
Chen, CS; Ozawa, H; Uematsu, T; Watanabe, H	1
Ozawa, H; Uematsu, T	1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J	1
Bevan, P; Bradshaw, CM; Szabadi, E	1
Chiba, S; Imai, Y	1
Fozard, JR; Mwaluko, GM	1
Antonelli, T; Beani, L; Bianchi, C; Caló, G; Ferioli, V; Gaist, G; Morari, M	1
Allen, JM; Hughes, G; McHale, NG; Thornbury, KD	1
Hernandez, DE; Jennes, L	1
Armour, JA; Butler, CK; Cardinal, R; Hopkins, DA; Murphy, DA; Smith, FM	1
Borsini, F; Giuliani, S; Gragnani, L; Lecci, A; Maggi, CA; Meli, A; Meli, P	1
Perel, JM; Somogyi, GT	1
Broadley, KJ; Grassby, PF	1
Buder, M; Fuder, H; Riers, HD; Rothacher, G	1
Ehrenström, F; Johansson, P	1
Bidziński, A; Hauptmann, M; Kostowski, W; Płaźnik, A; Tamborska, E	1
Hjemdahl, P; Kahan, T; Lundberg, JM; Pernow, J	1
Dhawan, KN; Gulati, A; Gupta, GP; Nath, C	1
Borsini, F; d'Aranno, V; Lecci, A; Mancinelli, A; Meli, A	1
Le Bras, YM; Pennec, JP	2
Dean, HA; Greenbaum, DS; Greenbaum, RB; Halvorsen, NA; Jerome, JA; Matson, RW; Mayle, JE; Mayor, JW; Stein, GE; Vanegeren, LE	1
Akah, PA	1
Chinn, C; Weber, LJ	1
Antonaccio, MJ	1
Barth, N; Muscholl, E	1
Hartmann, E	1
Buckley, JP; Cavero, I; Clarke, DE; Dixit, BN; Jandhyala, BS	1
Gyermek, L; Hill, RT; Sigg, EB	1
Garattini, S; Jori, A; Paglialunga, S	1
Bentley, GA; Li, DM	1
Barker, JL; Crayton, JW; Nicoll, RA	1
Farnebo, LO; Malamfors, T	1
Consolo, S; Garattini, S; Ladinsky, H; Peri, G	1
Hamilton, TC	1
Fuxe, K; Sjöqvist, F	1
Antonaccio, MJ; Robson, RD	1
Khoyi, MA; Pousti, A; Zarrindast, MR	1
Ghoneim, MM; Pandya, H	1
Carmichael, FJ; Israel, Y	1
Ross, G	1
Atkinson, J; Ladinsky, H	1
Gröningsson, K; Schill, G	1
Fuxe, K; Goldstein, M; Ljungdahl, A	1
Lippmann, W	1
Lapin, IP	1
Zetler, G	1
Vaillant, GE	1
Gillette, J; Sjöqvist, F	1
Koella, WP; Rubin, R; Schaeppi, U	1
Bhargava, KP; Gupta, ML; Gupta, TK	1
Dahlöf, C; Hjemdahl, P; Kahan, T	1
Doggrell, SA; Waldron, JB	1
Greenbaum, DS	1
Chung, C; Cook, P; Pendleton, RG; Risley, E; Williams, M	1
Levin, RM; Staskin, DR; Wein, AJ	1
Jones, RS; Olpe, HR; Steinmann, MW	1
Bräunlich, H; Fleck, C	1
de Champlain, J; Lavallée, M; Nadeau, RA	1
Miller, DA; Pendleton, RG; Ridley, PT	1
Barrington, M; Majewski, H	1
Starke, K; Stoffel, D; von Kügelgen, I	1
Björklund, A; Leanza, G; Nilsson, OG	1
Frank, MG; Heller, HC; Page, J	1
Bizot, JC	1
Fujii, T; Fujimoto, K; Kawashima, K; Nakai, K; Ohba, S; Suzuki, T	1
Gomita, Y; Nakagawa, T; Ohyama, T; Okamura, H; Ukai, K	1
BOFF, E; SCHECKEL, CL	1
LOEW, D; TAESCHLER, M	1
Dendorfer, A; Dominiak, P; Raasch, W; Ziegler, A	1

Reviews

3 review(s) available for atropine and desipramine

Article	Year
The role of receptor binding in drug discovery. Journal of natural products, 1993, Volume: 56, Issue:4 Topics: Animals; Drug Design; Humans; Receptors, Drug	1993
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacological studies of sleep and dreaming: chemical and clinical relationships. Biological psychiatry, 1969, Volume: 1, Issue:3 Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan	1969

Trials

2 trial(s) available for atropine and desipramine

Article	Year
Effects of desipramine on irritable bowel syndrome compared with atropine and placebo. Digestive diseases and sciences, 1987, Volume: 32, Issue:3 Topics: Adult; Aged; Atropine; Clinical Trials as Topic; Colon, Sigmoid; Colonic Diseases, Functional; Desipramine; Double-Blind Method; Female; Humans; Male; Manometry; Middle Aged; Placebos; Rectum; Time Factors	1987
Preliminary report on antidepressant treatment of irritable bowel syndrome: comments on comparison with anxiolytic therapy. Psychopharmacology bulletin, 1984,Fall, Volume: 20, Issue:4 Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Atropine; Clinical Trials as Topic; Colonic Diseases, Functional; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation	1984

Article

Year

Effects of desipramine on irritable bowel syndrome compared with atropine and placebo.

Digestive diseases and sciences, 1987, Volume: 32, Issue:3

Topics: Adult; Aged; Atropine; Clinical Trials as Topic; Colon, Sigmoid; Colonic Diseases, Functional; Desipramine; Double-Blind Method; Female; Humans; Male; Manometry; Middle Aged; Placebos; Rectum; Time Factors

1987

Preliminary report on antidepressant treatment of irritable bowel syndrome: comments on comparison with anxiolytic therapy.

Psychopharmacology bulletin, 1984,Fall, Volume: 20, Issue:4

Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Atropine; Clinical Trials as Topic; Colonic Diseases, Functional; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation

1984

Other Studies

99 other study(ies) available for atropine and desipramine

Article	Year
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. Journal of medicinal chemistry, 1989, Volume: 32, Issue:5 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship	1989
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors. Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes	1999
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Determination of log D via automated microfluidic liquid-liquid extraction. Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16 Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Pharmacologic analysis of chronotropic and inotropic responses to 5-hydroxytryptamine in the dog heart. Japanese journal of pharmacology, 1977, Volume: 27, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Atropine; Depression, Chemical; Desipramine; Dogs; Heart Rate; In Vitro Techniques; Methysergide; Myocardial Contraction; Propanolamines; Propranolol; Quinolines; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tetrodotoxin; Tyramine	1977
Tricyclic antidepressants and histamine H1 receptors. Mayo Clinic proceedings, 1979, Volume: 54, Issue:10 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic	1979
Effects of drugs on hyperactivity and aggression induced by raphe lesions in rats. Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:6 Topics: 5-Hydroxytryptophan; Aggression; Animals; Atropine; Brain Stem; Clomipramine; Desipramine; Humans; Imipramine; Male; Methyltyrosines; Motor Activity; Raphe Nuclei; Rats	1978
Mechanism of chronotropic and inotropic effects of phenylephrine. Japanese journal of pharmacology, 1977, Volume: 27, Issue:4 Topics: Alprenolol; Animals; Atropine; Depression, Chemical; Desipramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Heart Ventricles; In Vitro Techniques; Injections, Intra-Arterial; Levobunolol; Methoxamine; Myocardial Contraction; Phentolamine; Phenylephrine; Stimulation, Chemical; Tetrodotoxin	1977
Procaine-induced positive chronotropic and inotropic responses of the isolated, blood-perfused dog atrium. Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:1 Topics: Acetylcholine; Animals; Atropine; Desipramine; Dogs; Drug Interactions; Female; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nicotine; Norepinephrine; Procaine; Propranolol; Stimulation, Chemical; Tetrodotoxin; Tyramine	1977
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats. Japanese journal of pharmacology, 1977, Volume: 27, Issue:1 Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipramine; Drug Synergism; Guanethidine; Heart Rate; Hexamethonium Compounds; Injections, Intravenous; Injections, Subcutaneous; Male; Phentolamine; Rats; Reserpine	1977
Centrally mediated cardiovascular effects of intracisternal application of carbachol in anesthetized rats. Japanese journal of pharmacology, 1976, Volume: 26, Issue:3 Topics: Animals; Atropine; Blood Pressure; Carbachol; Chlorpromazine; Cisterna Magna; Desipramine; Drug Interactions; Hemodynamics; Hexamethonium Compounds; Injections; Male; Parasympathomimetics; Propranolol; Rats; Sympatholytics; Vagus Nerve	1976
On the anticataleptic action of cyproheptadine. Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2 Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone	1976
The effect of tricyclic antidepressants on cholinergic responses of single cortical neurones. British journal of pharmacology, 1975, Volume: 53, Issue:1 Topics: Acetylcholine; Action Potentials; Animals; Antidepressive Agents; Atropine; Carbachol; Cats; Cerebral Cortex; Desipramine; Female; Imipramine; In Vitro Techniques; Male; Neurons; Norepinephrine; Parasympathetic Nervous System; Serotonin	1975
Pharmacologic analysis of papaverine-induced positive chronotropic and inotropic effects. European journal of pharmacology, 1976, Volume: 35, Issue:1 Topics: Alprenolol; Animals; Atropine; Desipramine; Heart; Heart Rate; In Vitro Techniques; Manganese; Myocardial Contraction; Norepinephrine; Papaverine; Stimulation, Chemical; Tetrodotoxin; Tyramine	1976
Mechanism of the indirect sympathomimetic effect of 5-hydroxytrypt-amine on the isolated heart of the rabbit. British journal of pharmacology, 1976, Volume: 57, Issue:1 Topics: Animals; Atropine; Calcium; Colchicine; Desipramine; Dimethylphenylpiperazinium Iodide; Female; Heart; Heart Rate; Hydroxydopamines; In Vitro Techniques; Male; Norepinephrine; Rabbits; Serotonin; Sympathomimetics; Tetrodotoxin; Tyramine	1976
Comparison of [3H]choline and D-[3H]aspartate efflux from guinea pig and human neocortex. Journal of neurochemistry, 1992, Volume: 58, Issue:4 Topics: Animals; Aspartic Acid; Atropine; Cerebral Cortex; Choline; Desipramine; Dioxanes; Electric Stimulation; Guinea Pigs; Humans; Idazoxan; Norepinephrine; Reference Values; Tritium	1992
Nerve-mediated contractions of sheep mesenteric lymph node capsules. The Journal of physiology, 1990, Volume: 422 Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Desipramine; In Vitro Techniques; Isometric Contraction; Lymph Nodes; Muscle Contraction; Muscle, Smooth; Sheep; Tetrodotoxin; Time Factors	1990
Inhibition of neurotensin-induced miosis by blockade of ocular dopamine pathways. Journal of ocular pharmacology, 1990,Spring, Volume: 6, Issue:1 Topics: Animals; Atropine; Autonomic Nervous System; Desipramine; Dopamine; Dopamine Antagonists; Eye; Haloperidol; Hydroxydopamines; Iris; Miosis; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Nerve Endings; Neurotensin; Neurotransmitter Agents; Oxidopamine; Rabbits; Receptors, Opioid, mu	1990
Cardiac responses to electrical stimulation of discrete loci in canine atrial and ventricular ganglionated plexi. The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 2 Topics: Animals; Atropine; Denervation; Desipramine; Dogs; Female; Ganglia; Ganglionic Blockers; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Hexamethonium; Hexamethonium Compounds; Male	1990
Effect of acute or chronic administration of imipramine on spinal and supraspinal micturition reflexes in rats. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1 Topics: Animals; Atropine; Desipramine; Enuresis; Fenclonine; Imipramine; Male; Rats; Receptors, Serotonin; Reflex; Spinal Cord; Urinary Bladder; Urination	1989
Antagonism by tricyclic antidepressants of the muscarinic receptors located on the adrenergic nerve endings in rabbit heart atrium. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3 Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Desipramine; Electric Stimulation; Heart; Imipramine; Male; Norepinephrine; Nortriptyline; Oxotremorine; Parasympatholytics; Rabbits; Receptors, Muscarinic; Sympathetic Nervous System	1989
Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:4 Topics: Animals; Atropine; Carbachol; Desipramine; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Male; Muscle, Smooth; Norepinephrine; Potassium Chloride; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1985
On the opioid receptor subtype inhibiting the evoked release of 3H-noradrenaline from guinea-pig atria in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2 Topics: Animals; Atropine; Benzomorphans; Binding, Competitive; Corticosterone; Cyclazocine; Desipramine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Heart Atria; In Vitro Techniques; Morphine; Myocardium; Naloxone; Norepinephrine; Peptide Fragments; Phentolamine; Receptors, Opioid; Receptors, Opioid, kappa; Synapses	1986
Presynaptic alpha-adrenoceptor regulation of transmitter release in the conscious rat. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 89, Issue:1 Topics: Adrenal Medulla; Animals; Atropine; Blood Pressure; Desipramine; Heart Rate; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stress, Physiological; Synapses; Yohimbine	1988
Brain neurotransmitter systems mediating behavioral deficits produced by inescapable shock treatment in rats. Brain research, 1988, Apr-26, Volume: 447, Issue:1 Topics: Alanine; Amphetamine; Animals; Antidepressive Agents; Atropine; Brain; Desipramine; Diazepam; Electroshock; Escape Reaction; Male; Motor Activity; Neurotransmitter Agents; Physostigmine; Rats; Rats, Inbred Strains; Valproic Acid	1988
Possible involvement of neuropeptide Y in sympathetic vascular control of canine skeletal muscle. Acta physiologica Scandinavica, 1988, Volume: 132, Issue:1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Desipramine; Dogs; Electric Stimulation; Female; Male; Muscles; Neuropeptide Y; Norepinephrine; Phenoxybenzamine; Sympathetic Nervous System; Vasoconstriction	1988
Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice. Life sciences, 1988, Volume: 42, Issue:24 Topics: Animals; Atropine; Central Nervous System; Cimetidine; Depression; Desipramine; Disease Models, Animal; Histamine; Imidazoles; Imipramine; Impromidine; Male; Mice; Motor Activity; Pyrilamine; Receptors, Histamine H2	1988
Cholinergic drug effects on antidepressant-induced behaviour in the forced swimming test. European journal of pharmacology, 1988, Dec-13, Volume: 158, Issue:3 Topics: Animals; Antidepressive Agents; Atropine; Behavior, Animal; Desipramine; Drug Synergism; Male; Motor Activity; Nomifensine; Pharmaceutical Vehicles; Physical Exertion; Physostigmine; Rats; Scopolamine; Swimming	1988
Diel and seasonal rhythms of the heart rate in the common eel (Anguilla anguilla L.): role of cardiac innervation. Experimental biology, 1988, Volume: 47, Issue:3 Topics: Acetylcholine; Anguilla; Animals; Atropine; Catecholamines; Circadian Rhythm; Desipramine; Electrocardiography; Electronic Data Processing; Fourier Analysis; Heart; Heart Rate; Propranolol; Seasons; Sympathetic Nervous System	1988
Tricyclic antidepressant inhibition of the electrical evoked responses of the rat urinary bladder strip-effect of variation in extracellular Ca2+ concentration. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:2 Topics: Amitriptyline; Animals; Atropine; Calcium; Desipramine; Drug Synergism; Electric Stimulation; Female; In Vitro Techniques; Male; Rats; Urinary Bladder	1986
The actions of several psychoactive agents upon the muscarinic mechanisms in the superior cervical ganglion of the cat. Neuropharmacology, 1974, Volume: 13, Issue:1 Topics: Alkynes; Animals; Atropine; Carbamates; Cats; Desipramine; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Ganglia, Autonomic; Ganglia, Spinal; Heart Rate; Hexamethonium Compounds; Hydrazines; Injections, Intra-Arterial; Male; Methylphenidate; Muscle Contraction; Nictitating Membrane; Nortriptyline; Parasympathetic Nervous System; Parasympathomimetics; Pargyline; Piperidines; Quaternary Ammonium Compounds	1974
Paradoxical vagal tachycardia in ganglion-blocked anesthetized dogs. European journal of pharmacology, 1974, Volume: 28, Issue:1 Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chlorisondamine; Debrisoquin; Desipramine; Dogs; Drug Interactions; Electric Stimulation; Female; Ganglionic Blockers; Guanethidine; Heart Rate; Hexamethonium Compounds; Male; Mecamylamine; Methylphenidate; Oxprenolol; Reserpine; Vagus Nerve	1974
The effects of the tricyclic antidepressants desipramine, doxepin and iprindole on the isolated perfused rabbit heart. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 284, Issue:3 Topics: Animals; Antidepressive Agents; Arrhythmias, Cardiac; Atropine; Autonomic Fibers, Postganglionic; Cocaine; Desipramine; Doxepin; Drug Antagonism; Electric Stimulation; Female; Heart; Heart Rate; Iprindole; Male; Perfusion; Propranolol; Quinidine; Rabbits; Sympathetic Nervous System; Time Factors	1974
A differential effect of chronically administered guanethidine on sympathetic neurotransmission to the dog heart and mesenteric arterial blood vessels. Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chlorisondamine; Cocaine; Desipramine; Dogs; Drug Synergism; Electrodes, Implanted; Guanethidine; Heart; Heart Rate; Hexamethonium Compounds; In Vitro Techniques; Mesenteric Arteries; Monoamine Oxidase; Myocardium; Norepinephrine; Phentolamine; Sympathetic Nervous System; Synaptic Transmission; Vasomotor System	1974
Antagonism to reserpine induced depression by imipramine, related psychoactive drugs, and some autonomic agents. Psychopharmacologia, 1965, Feb-15, Volume: 7, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Behavior, Animal; Cyproheptadine; Desipramine; Diphenhydramine; Hallucinogens; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Mice; Promazine; Psychopharmacology; Reserpine; Serotonin	1965
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine. Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine	1967
Reflex vascular responses to vasoactive substances. European journal of pharmacology, 1970, Volume: 12, Issue:2 Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Atropine; Blood Vessels; Carotid Sinus; Cats; Chemoreceptor Cells; Constriction; Denervation; Desipramine; Dextroamphetamine; Dilatation; Dopamine; Epinephrine; Female; Ganglionic Blockers; Hindlimb; Histamine; Histamine H1 Antagonists; Male; Nerve Endings; Norepinephrine; Perfusion; Pressoreceptors; Pyrroles; Reflex; Sympathetic Nervous System; Tachyphylaxis; Tripelennamine; Vagotomy; Vagus Nerve; Veratrine	1970
Noradrenaline and acetylcholine responses of supraoptic neurosecretory cells. The Journal of physiology, 1971, Volume: 218, Issue:1 Topics: Acetylcholine; Adrenergic beta-Antagonists; Alkaloids; Amino Alcohols; Anilides; Animals; Atropine; Carbachol; Cats; Depression, Chemical; Desipramine; Dopamine; Drug Synergism; Hypothalamo-Hypophyseal System; Hypothalamus; Methacholine Compounds; Nerve Endings; Neurosecretion; Nicotine; Norepinephrine; Physostigmine; Serotonin; Sulfonamides	1971
3 H-noradrenaline release and mechanical response in the field stimulated mouse vas deferens. Acta physiologica Scandinavica. Supplementum, 1971, Volume: 371 Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Buffers; Desipramine; Dopamine; Electric Stimulation; Male; Methods; Methoxamine; Mice; Muscle Contraction; Neurons; Norepinephrine; Sensory Receptor Cells; Stimulation, Chemical; Sympatholytics; Synaptic Transmission; Tetrodotoxin; Time Factors; Tritium; Vas Deferens	1971
Effect of central stimulants and depressants on mouse brain acetylcholine and choline levels. European journal of pharmacology, 1972, Volume: 18, Issue:2 Topics: Acetylcholine; Amphetamine; Animals; Atropine; Brain Chemistry; Central Nervous System Stimulants; Chlorpromazine; Choline; Depression, Chemical; Desipramine; Diazepam; Haloperidol; Ketones; Male; Mice; Pentobarbital; Pentylenetetrazole; Physostigmine; Reserpine; Stimulation, Chemical; Tranquilizing Agents; Tremorine	1972
Effects of dopamine on the conductance of perfused vascular beds of the chloralosed cat. British journal of pharmacology, 1972, Volume: 44, Issue:3 Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Cats; Cocaine; Constriction; Desipramine; Dilatation; Dopamine; Dopamine Antagonists; Drug Synergism; Female; Haloperidol; Heart Rate; Hindlimb; Histamine H1 Antagonists; Isoproterenol; Male; Perfusion; Phenoxybenzamine; Propranolol; Receptors, Adrenergic; Vascular Resistance	1972
Hypothermic effect of apomorphine in the mouse. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:9 Topics: Amines; Animals; Apomorphine; Atropine; Body Temperature; Depression, Chemical; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Haloperidol; Male; Mice; Phenoxybenzamine; Pimozide; Receptors, Drug	1972
Pharmacological alterations of vagally induced tachycardia in anesthetized dogs. European journal of pharmacology, 1974, Volume: 25, Issue:1 Topics: Animals; Atropine; Blood Pressure; Chlorisondamine; Desipramine; Dogs; Electric Stimulation; Female; Guanethidine; Heart Rate; Hexamethonium Compounds; Male; Norepinephrine; Oxprenolol; Reserpine; Sympathetic Nervous System; Time Factors; Vagus Nerve	1974
Effect of desmethylimipramine on the canine SA node. The Tohoku journal of experimental medicine, 1974, Volume: 113, Issue:4 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Depression, Chemical; Desipramine; Dogs; Electrocardiography; Female; Heart Rate; Male; Norepinephrine; Propranolol; Sinoatrial Node; Stimulation, Chemical; Tetrodotoxin; Tyramine	1974
The effect of ethacrynic acid on the guinea-pig and rat isolated vas deferens. British journal of pharmacology, 1974, Volume: 52, Issue:4 Topics: Animals; Atropine; Cocaine; Desipramine; Ethacrynic Acid; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Rats; Reserpine; Vas Deferens	1974
Plasma protein binding of bupivacaine and its interaction with other drugs in man. British journal of anaesthesia, 1974, Volume: 46, Issue:6 Topics: Atropine; Binding, Competitive; Blood Proteins; Bupivacaine; Desipramine; Dialysis; Drug Interactions; Heparin; Humans; Meperidine; Phenytoin; Protein Binding; Quinidine	1974
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2 Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium	1973
Effects of intracoronary infusions of acetylcholine and nicotine on the dog heart in vivo. British journal of pharmacology, 1973, Volume: 48, Issue:4 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Coronary Vessels; Desipramine; Dogs; Electric Stimulation; Heart; Heart Rate; Injections, Intra-Arterial; Nicotine; Phenoxybenzamine; Sympathetic Nervous System	1973
A quantitative study of the anticholinergic action of several tricyclic antidepressants on the rat isolated fundal strip. British journal of pharmacology, 1972, Volume: 45, Issue:3 Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Dibenzocycloheptenes; Dimethylamines; Female; In Vitro Techniques; Mathematics; Muscle Contraction; Opipramol; Parasympatholytics; Rats; Stomach	1972
Thin-layer chromatography of ion pairs on impregnated layers. Acta pharmaceutica Suecica, 1969, Volume: 6, Issue:4 Topics: Alkaloids; Amitriptyline; Atropine; Chromatography, Thin Layer; Desipramine; Imipramine; Ions; Scopolamine	1969
Antiparkinsonian drugs and central dopamine neurons. Life sciences. Pt. 1: Physiology and pharmacology, 1970, Jul-15, Volume: 9, Issue:14 Topics: Animals; Atropine; Behavior, Animal; Brain; Catecholamines; Desipramine; Dihydroxyphenylalanine; Dopamine; Fluorometry; Male; Neurons; Nialamide; Parasympatholytics; Rats; Reserpine; Tropanes	1970
Blockade of norepinephrine uptake and related activities of cis- and trans-N,N'-bis-(1-naphthylmethyl)-1,4-cyclohexane bis-(methylamine) dihydrochloride. Biochemical pharmacology, 1970, Volume: 19, Issue:5 Topics: Adipose Tissue; Amines; Animals; Atropine; Chlorpromazine; Cyclohexanes; Desipramine; Drug Antagonism; Epididymis; Eyelids; Female; Hypnotics and Sedatives; Imipramine; Lacrimal Apparatus; Lipid Mobilization; Male; Mathematics; Metaraminol; Methyltyrosines; Mice; Motor Activity; Muscles; Myocardium; Naphthalenes; Norepinephrine; Rats; Species Specificity; Stereoisomerism; Tetrabenazine; Time Factors; Tremor; Tremorine; Tritium	1970
Simple pharmacological procedures to differentiate antidepressants and cholinolytics in mice and rats. Psychopharmacologia, 1967, Volume: 11, Issue:1 Topics: Aggression; Animals; Antidepressive Agents; Atropine; Benactyzine; Desipramine; Exploratory Behavior; Female; Humans; Imipramine; Male; Methods; Mice; Motor Activity; Parasympatholytics; Rats; Reserpine	1967
Cataleptic state and hypothermia in mice, caused by central cholinergic stimulation and antagonized by anticholinergic and antidepressant drugs. International journal of neuropharmacology, 1968, Volume: 7, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Catalepsy; Desipramine; Hexamethonium Compounds; Humans; Hypothermia; Imipramine; Male; Mice; Nicotine; Nicotinic Acids; Nitrophenols; Parasympatholytics; Parasympathomimetics; Phosphoric Acids; Pilocarpine; Pralidoxime Compounds; Scopolamine; Tremorine	1968
Clinical significance of anticholinergic effects of imipramine-like drugs. The American journal of psychiatry, 1969, Volume: 125, Issue:11 Topics: Amitriptyline; Animals; Atropine; Columbidae; Depression; Desipramine; Diphenhydramine; Humans; Imipramine; Parasympatholytics; Scopolamine	1969
Prolongation and potentiation of oxotremorine effects by desmethylimipramine an "anti-tremorine" drug. Life sciences, 1965, Volume: 4, Issue:10 Topics: Animals; Atropine; Desipramine; Drug Synergism; Proadifen; Rats; Tremor; Tremorine	1965
Effects of serotonin upon the isolated iris sphincter of the cat. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3 Topics: Acetylcholine; Animals; Atropine; Cats; Creatine; Desipramine; Electric Stimulation; Electrophysiology; In Vitro Techniques; Iproniazid; Iris; Isoproterenol; Methysergide; Morphine; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phentolamine; Physostigmine; Pyrogallol; Serotonin; Sympathectomy	1967
Central anticholinergic activity of imipramine and allied drugs. Canadian journal of physiology and pharmacology, 1967, Volume: 45, Issue:2 Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Female; Imipramine; Male; Mice; Parasympatholytics; Seizures	1967
Relationship between the overflow of endogenous and radiolabelled noradrenaline from canine blood perfused gracilis muscle. Acta physiologica Scandinavica, 1984, Volume: 122, Issue:4 Topics: Animals; Atropine; Desipramine; Dogs; Dopamine; Epinephrine; Female; Male; Muscles; Neurons; Norepinephrine; Perfusion; Phenoxybenzamine; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction	1984
Effect of cocaine on tone and contractile responses to acetylcholine in the rat anococcygeus muscle. The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:6 Topics: Acetylcholine; Animals; Atropine; Cocaine; Desipramine; Drug Interactions; Male; Muscle Contraction; Neostigmine; Ouabain; Phentolamine; Rats; Rats, Inbred Strains	1982
Storage and release of catecholamines by nervous endings in the isolated heart of the eel (Anguilla anguilla L.). Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 77, Issue:1 Topics: Action Potentials; Anguilla; Animals; Atropine; Blood Pressure; Catecholamines; Desipramine; Electric Stimulation; Heart; Heart Rate; Nerve Endings; Perfusion; Propranolol; Systole; Vagus Nerve	1984
Comparison of central gastric antisecretory effects of desmethylimipramine, doxepin and pirenzepine in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:3 Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Brain; Chlorpromazine; Desipramine; Doxepin; Gastric Acid; Male; Pirenzepine; Rats; Rats, Inbred Strains	1984
Analysis of the anticholinergic and musculotropic effects of desmethylimipramine on the rabbit urinary bladder. Urological research, 1983, Volume: 11, Issue:6 Topics: Animals; Atropine; Bethanechol Compounds; Desipramine; Male; Muscle Contraction; Muscle Relaxation; Quinuclidinyl Benzilate; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Stimulation, Chemical; Urinary Bladder	1983
The locus coeruleus: actions of psychoactive drugs. Experientia, 1983, Mar-15, Volume: 39, Issue:3 Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine	1983
Failure of physostigmine in intoxications with tricyclic antidepressants in rats. Toxicology, 1982, Volume: 24, Issue:3-4 Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Clomipramine; Desipramine; Drug Interactions; Female; Heart Rate; Imipramine; Lethal Dose 50; Physostigmine; Rats; Rats, Inbred Strains; Respiration; Time Factors	1982
Reflexly induced inhibition of catecholamine release through a peripheral muscarinic mechanism. Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:11 Topics: Animals; Atropine; Blood Pressure; Catecholamines; Desipramine; Dogs; Edrophonium; Female; Heart Rate; Male; Receptors, Cholinergic; Receptors, Muscarinic; Sotalol	1980
Studies on the putative anticholinergic effects of desmethylimipramine. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 243, Issue:1 Topics: Animals; Atropine; Blepharoptosis; Carbachol; Defecation; Desipramine; Gastric Juice; Male; Mice; Mydriatics; Oxotremorine; Parasympatholytics; Rats; Salivation	1980
Trifluoperazine and calmidazolium have multiple actions on the release of noradrenaline from sympathetic nerves of mouse atria. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine; Calmodulin; Desipramine; Electric Stimulation; Enterochromaffin Cells; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Male; Mice; Myocardium; Norepinephrine; Phentolamine; Sympathetic Nervous System; Trifluoperazine	1994
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria. British journal of pharmacology, 1995, Volume: 115, Issue:2 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine	1995
Compensatory changes of in vivo acetylcholine and noradrenaline release in the hippocampus after partial deafferentation, as monitored by microdialysis. Brain research, 1993, Jun-25, Volume: 615, Issue:1 Topics: Acetylcholine; Animals; Atropine; Choline O-Acetyltransferase; Denervation; Desipramine; Dialysis; Female; Hippocampus; Immunohistochemistry; Models, Neurological; Neostigmine; Nerve Regeneration; Neural Pathways; Neurons, Afferent; Neurotransmitter Agents; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Synaptic Transmission	1993
The effects of REM sleep-inhibiting drugs in neonatal rats: evidence for a distinction between neonatal active sleep and REM sleep. Brain research, 1997, Dec-05, Volume: 778, Issue:1 Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Arousal; Atropine; Behavior, Animal; Desipramine; Electroencephalography; Electromyography; Muscarinic Antagonists; Rats; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep, REM; Synapses; Zimeldine	1997
Effects of psychoactive drugs on temporal discrimination in rats. Behavioural pharmacology, 1997, Volume: 8, Issue:4 Topics: Animals; Atropine; Clomipramine; Desipramine; Diazepam; Discrimination Learning; Discrimination, Psychological; Haloperidol; Male; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar; Scopolamine	1997
Enhancement of the serotonin-mediated acetylcholine release by repeated desmethylimipramine treatment in the hippocampus of freely moving rats. Japanese journal of pharmacology, 1999, Volume: 80, Issue:4 Topics: Acetylcholine; Adrenergic Uptake Inhibitors; Animals; Atropine; Desipramine; Drug Synergism; Hippocampus; Male; Microdialysis; Parasympatholytics; Perfusion; Radioimmunoassay; Rats; Rats, Wistar; Serotonin; Skull; Time Factors; Vasodilator Agents	1999
Effect of dopaminergic drugs on the reserpine-induced lowering of hippocampal theta wave frequency in rats. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2000, Volume: 20, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Atropine; Bupropion; Cyclobutanes; Desipramine; Dopamine Agents; Dopamine Agonists; Hippocampus; Male; Methamphetamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Reserpine; Theta Rhythm	2000
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE. Psychopharmacologia, 1964, Feb-12, Volume: 5 Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine	1964
[RESEARCH ON ANTICHOLINERGIC EFFECTS OF ANTIDEPRESSIVE SUBSTANCES IN THE RABBIT]. Helvetica physiologica et pharmacologica acta, 1964, Volume: 64 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Bradycardia; Cholinergic Antagonists; Desipramine; Imipramine; Parasympatholytics; Pharmacology; Rabbits; Research; Salivation; Sialorrhea	1964
Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 44, Issue:3 Topics: Adrenergic alpha-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desipramine; Diastole; Dose-Response Relationship, Drug; Losartan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reserpine; Sympathectomy, Chemical; Sympathetic Nervous System; Symporters; Tetrazoles; Tubocurarine; Yohimbine	2004