Compounds > atropine
Page last updated: 2024-09-05

atropine and deferoxamine

atropine has been researched along with deferoxamine in 11 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(deferoxamine)		Trials
(deferoxamine)		Recent Studies (post-2010) (deferoxamine)
26,7111,2591,6976,7032401,266

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)deferoxamine (IC50)
Lysine-specific demethylase 4AHomo sapiens (human)3.275
Deoxyhypusine hydroxylaseHomo sapiens (human)5

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's3 (27.27)18.2507
2000's0 (0.00)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chen, X; Gillis, CN1
Ellis, EF; Hess, ML; Kontos, HA; Kukreja, RC; Wei, EP1
Wirth, W1
Goulding, R1
Bowden, CA; Krenzelok, EP1
Anuvarbekova, A; Ercan, ZS; Fincan, GS; Ozger, SI; Sarioglu, Y; Utkan, T; Vural, IM1

Reviews

2 review(s) available for atropine and deferoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical applications of commonly used contemporary antidotes. A US perspective.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer

1997

Other Studies

9 other study(ies) available for atropine and deferoxamine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effect of free radicals on pulmonary vascular response to acetylcholine.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Atropine; Calcimycin; Catalase; Deferoxamine; Endothelium, Vascular; Free Radicals; Male; Muscle, Smooth, Vascular; Nitroprusside; Perfusion; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Rabbits; Sodium Salicylate; Superoxide Dismutase; Vasoconstriction; Vasodilation

1991
Differences in endothelium-dependent cerebral dilation by bradykinin and acetylcholine.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 2

    Topics: Acetylcholine; Amitrole; Animals; Arterioles; Atropine; Bradykinin; Cats; Cerebrovascular Circulation; Deferoxamine; Endothelium, Vascular; Indomethacin; Nitric Oxide; Prostaglandin Endoperoxides; Prostaglandins; Vasodilation

1990
[Possible side-effects of antidotal therapy].
    Archiv fur Toxikologie, 1968, Volume: 24, Issue:1

    Topics: Antidotes; Atropine; Chelating Agents; Cyanides; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Hydroxocobalamin; Metals; Nitrites; Penicillamine; Pentetic Acid; Phenols; Phosphates; Poisoning; Pralidoxime Compounds; Thiosulfates

1968
The treatment of acute poisoning.
    Transactions of the Medical Society of London, 1967, Volume: 83

    Topics: Acute Disease; Antidotes; Atropine; Barbiturates; Carbon Monoxide Poisoning; Chlorpromazine; Deferoxamine; England; Gastric Lavage; Heart Massage; Humans; Meperidine; Morphine; Oxygen; Paraldehyde; Phenobarbital; Poisoning; Salicylates; Suicide; Wales

1967
Investigation of enhancement effects of nicotine on cholinergic neurotransmission in isolated rabbit gastric fundus: role of antioxidants.
    Autonomic & autacoid pharmacology, 2010, Volume: 30, Issue:3

    Topics: Acetylcholine; Allopurinol; Animals; Antioxidants; Atropine; Cholinergic Fibers; Deferoxamine; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Mannitol; Muscle Contraction; Muscle, Smooth; Neostigmine; Nicotine; Rabbits; Reactive Oxygen Species; Synaptic Transmission; Tetrodotoxin

2010