Page last updated: 2024-09-05

atropine and cyclohexyl methylphosphonofluoridate

atropine has been researched along with cyclohexyl methylphosphonofluoridate in 18 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(cyclohexyl methylphosphonofluoridate)
Trials
(cyclohexyl methylphosphonofluoridate)
Recent Studies (post-2010) (cyclohexyl methylphosphonofluoridate)
26,7111,2591,697143067

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (38.89)18.2507
2000's10 (55.56)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dochterman, LW; Gresham, VC; Kaminskis, A; Koplovitz, I; Stewart, JR1
Clement, JG2
Koplovitz, I; Young, GD1
Bajgar, J; Kassa, J1
Liang, J; Luo, C1
Cabal, J; Kassa, J1
McDonough, JH; Shih, TM1
Krejcová-Kunesová, G; Kuca, K; Sevelová, L1
Berger, BJ; Davidson, C; Hamilton, MG; Hill, I; Lecavalier, P; Lundy, PM; Vair, C; Weatherby, KL1
Bartosová, L; Kuca, K; Kunesová, G; Vachek, J1
Bajgar, J; Jun, D; Kassa, J; Kuca, K1
Humlicek, V; Kassa, J1
Koplovitz, I; Maxwell, DM; Sweeney, RE; Worek, F1
Bajgar, J; Karasova, J; Kassa, J; Kuca, K; Musilek, K1
Bajgar, J; Karasova, JZ; Kassa, J; Kuca, K; Musilek, K; Tesarova, S1
Karasova, JZ; Kassa, J; Kuca, K; Musilek, K; Novotny, L; Pohanka, M1
Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM; Williams, RL1

Other Studies

18 other study(ies) available for atropine and cyclohexyl methylphosphonofluoridate

ArticleYear
Evaluation of the toxicity, pathology, and treatment of cyclohexylmethylphosphonofluoridate (CMPF) poisoning in rhesus monkeys.
    Archives of toxicology, 1992, Volume: 66, Issue:9

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide

1992
Efficacy of various oximes against GF (cyclohexyl methylphosphonofluoridate) poisoning in mice.
    Archives of toxicology, 1992, Volume: 66, Issue:2

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; In Vitro Techniques; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nervous System Diseases; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds

1992
Acute toxicity of cyclohexylmethylphosphonofluoridate (CMPF) in rhesus monkeys: serum biochemical and hematologic changes.
    Archives of toxicology, 1995, Volume: 69, Issue:6

    Topics: Alanine Transaminase; Animals; Antidotes; Aspartate Aminotransferases; Atropine; Biomarkers; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Creatine Kinase; Injections, Intramuscular; L-Lactate Dehydrogenase; Lethal Dose 50; Macaca mulatta; Male; Organophosphorus Compounds; Oximes; Potassium; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Seizures

1995
Toxicity of the combined nerve agents GB/GF in mice: efficacy of atropine and various oximes as antidotes.
    Archives of toxicology, 1994, Volume: 68, Issue:1

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Drug Synergism; Injections, Subcutaneous; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Poisoning; Sarin

1994
Comparison of the efficacy of HI-6 and obidoxime against cyclohexyl methylphosphonofluoridate (GF) in rats.
    Human & experimental toxicology, 1995, Volume: 14, Issue:11

    Topics: Acetylcholinesterase; Animals; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Corticosterone; Diaphragm; Drug Interactions; Liver; Male; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Tyrosine Transaminase

1995
Evaluation of combined toxic effects of GB/GF and efficacy of jielin injection against combined poisoning in mice.
    Toxicology letters, 1997, Aug-22, Volume: 92, Issue:3

    Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Cholinesterase Reactivators; Female; Humans; Injections; Male; Mice; Organophosphorus Compounds; Pralidoxime Compounds; Sarin; Software

1997
A comparison of the efficacy of acetylcholinesterase reactivators against cyclohexyl methylphosphonofluoridate (GF agent) by in vitro and in vivo methods.
    Pharmacology & toxicology, 1999, Volume: 84, Issue:1

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Drug Interactions; Enzyme Reactivators; In Vitro Techniques; Male; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Survival Rate

1999
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
    Archives of toxicology, 2000, Volume: 74, Issue:3

    Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman

2000
Antidotal treatment of GF-agent intoxication in mice with bispyridinium oximes.
    Toxicology, 2005, Feb-01, Volume: 207, Issue:1

    Topics: Animals; Antidotes; Atropine; Disease Models, Animal; Female; Injections, Intramuscular; Lethal Dose 50; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Structure-Activity Relationship

2005
The pharmacokinetics and pharmacodynamics of two HI-6 salts in swine and efficacy in the treatment of GF and soman poisoning.
    Toxicology, 2005, Mar-30, Volume: 208, Issue:3

    Topics: Animals; Atropine; Chemical Warfare Agents; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neuroprotective Agents; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Soman; Swine; Time Factors

2005
Therapeutic efficacy of different antidotal mixtures against poisoning with GF-agent in mice.
    Acta medica (Hradec Kralove), 2004, Volume: 47, Issue:4

    Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Female; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes

2004
Comparison of reactivating and therapeutic efficacy of two salts of the oxime HI-6 against tabun, soman and cyclosarin in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:5

    Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Male; Muscarinic Antagonists; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Soman

2007
A comparison of the potency of newly developed oximes (K074, K075) and currently available oximes (obidoxime, trimedoxime, HI-6) to counteract acute toxic effects of tabun and cyclosarin in mice.
    Drug and chemical toxicology, 2008, Volume: 31, Issue:1

    Topics: Animals; Antidotes; Atropine; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Trimedoxime

2008
A structure-activity analysis of the variation in oxime efficacy against nerve agents.
    Toxicology and applied pharmacology, 2008, Sep-01, Volume: 231, Issue:2

    Topics: Acetylcholinesterase; Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Guinea Pigs; Linear Models; Male; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Structure-Activity Relationship

2008
An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:1

    Topics: Animals; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Molecular Structure; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Treatment Outcome

2009
Evaluation of the neuroprotective efficacy of newly developed oximes (K206, K269) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:3

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Muscarinic Antagonists; Neuroprotective Agents; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar

2009
Effect of seven newly synthesized and currently available oxime cholinesterase reactivators on cyclosarin-intoxicated rats.
    International journal of molecular sciences, 2009, Jul-07, Volume: 10, Issue:7

    Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Male; Organophosphorus Compounds; Oximes; Rats; Rats, Wistar

2009
Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice.
    Toxicology, 2018, 09-01, Volume: 408

    Topics: Animals; Atropine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Time Factors

2018