atropine has been researched along with cp 96345 in 23 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (cp 96345) | Trials (cp 96345) | Recent Studies (post-2010) (cp 96345) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 403 | 1 | 16 |
| Protein | Taxonomy | atropine (IC50) | cp 96345 (IC50) |
|---|---|---|---|
| Substance-P receptor | Homo sapiens (human) | 0.0028 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (95.65) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gomi, Y; Suzuki, N | 1 |
| Cadieux, A; Claing, A; D'Orléans-Juste, P; Fournier, A; Regoli, D; Télémaque, S | 1 |
| Ballati, L; Evangelista, S; Maggi, CA; Manzini, S | 1 |
| Advenier, C; Hirsch, A; Martin, CA; Molimard, M; Naline, E | 1 |
| Joos, GF; Kips, JC; Pauwels, RA | 1 |
| Corsi, M; Gaviraghi, G; Oliosi, B; Palea, S; Pietra, C; Sugg, E; Trist, DG; Van Amsterdam, FT | 1 |
| Gomi, Y; Mizuno, K; Suzuki, N | 1 |
| Barthó, L; Lefebvre, R | 1 |
| Bueno, L; Fargeas, MJ; Fioramonti, J | 1 |
| Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Pellegrini, CA | 1 |
| Bertrand, C; Geppetti, P; Graf, PD; Nadel, JA | 1 |
| Carraway, RE; Mitra, SP | 1 |
| Gertner, SB; Selig, WM; Tocker, JE; Welton, AF | 1 |
| Bertrand, C; Foresi, A; Geppetti, P; Graf, PD; Nadel, JA | 1 |
| Barnes, JC; Hawcock, AB | 1 |
| Bhaskar, KR; Castagliuolo, I; Fleming, SM; Kornetsky, C; Lamont, JT; Nikulasson, ST; Pothoulakis, C; Qiu, B | 1 |
| Chirtel, SJ; Field, RB; Redman, RS | 1 |
| Hsu, TH; Kou, YR; Lai, YL | 2 |
| Broussard, DL; Feng, HS; Ouyang, A | 1 |
| Freire-Maia, L; Leite, R; Matos, IM; Teixeira, MM | 1 |
| Mori, M; Tsushima, H | 1 |
| Ho, CY; Kou, YR | 1 |
23 other study(ies) available for atropine and cp 96345
| Article | Year |
|---|---|
Effects of CP-96,345, a novel non-peptide antagonist of NK1 receptor, on the peristalsis in isolated guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Ileum; In Vitro Techniques; Male; Peristalsis; Receptors, Neurokinin-1; Receptors, Neurotransmitter | 1992 |
Nonadrenergic and noncholinergic arterial dilatation and venoconstriction are mediated by calcitonin gene-related peptide1 and neurokinin-1 receptors, respectively, in the mesenteric vasculature of the rat after perivascular nerve stimulation.
Topics: Animals; Atropine; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Electric Stimulation; Male; Mesenteric Arteries; Mesenteric Veins; Methysergide; Rats; Receptors, Calcitonin; Receptors, Cell Surface; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Splanchnic Circulation; Vasoconstriction; Vasodilation | 1992 |
Effects of selective tachykinin receptor antagonists on capsaicin- and tachykinin-induced bronchospasm in anaesthetized guinea-pigs.
Topics: Anesthesia; Animals; Atropine; Biphenyl Compounds; Bronchial Spasm; Capsaicin; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Male; Neurokinin A; Peptide Fragments; Receptors, Neurotransmitter; Receptors, Tachykinin; Tachykinins | 1992 |
Contractile effects of bradykinin on the isolated human small bronchus.
Topics: Acetylcholine; Aged; Atropine; Benzamides; Biphenyl Compounds; Bradykinin; Bronchi; Bronchoconstriction; Capsaicin; Humans; In Vitro Techniques; Indomethacin; Middle Aged; Muscle, Smooth; Nerve Fibers; Neurokinin A; Neurons, Afferent; Piperidines; Receptors, Bradykinin; Ruthenium Red; Tetrodotoxin | 1994 |
In vivo characterization of the tachykinin receptors involved in the direct and indirect bronchoconstrictor effect of tachykinins in two inbred rat strains.
Topics: Airway Resistance; Animals; Atropine; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Methysergide; Neurokinin A; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Serotonin; Substance P; Thiorphan | 1994 |
A further analysis of the contraction induced by activation of cholecystokinin A receptors in guinea pig isolated ileum longitudinal muscle-myenteric plexus.
Topics: Animals; Atropine; Biphenyl Compounds; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neuromuscular Junction; Peptide Fragments; Peptides, Cyclic; Physalaemin; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Substance P; Tetragastrin; Tetrodotoxin | 1994 |
Tachykinin-induced contractions in the circular muscle of guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Structure-Activity Relationship; Substance P; Tachykinins; Tetrodotoxin | 1994 |
Nitric oxide induces acetylcholine-mediated contractions in the guinea-pig small intestine.
Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Substance P; Tetrodotoxin | 1994 |
Involvement of capsaicin-sensitive afferent nerves in the intestinal motor alterations induced by intestinal anaphylaxis in rats.
Topics: Afferent Pathways; Anaphylaxis; Animals; Atropine; Biphenyl Compounds; Capsaicin; Electromyography; Female; Gastrointestinal Motility; Intestine, Small; Muscle, Smooth; Ovalbumin; Rats; Substance P | 1993 |
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors.
Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Esophagus; Glycopeptides; Humans; Isometric Contraction; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin | 1993 |
Capsaicin increases airflow resistance in guinea pigs in vivo by activating both NK2 and NK1 tachykinin receptors.
Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Male; Neurokinin A; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1993 |
Binding and biologic activity of neurotensin in guinea pig ileum.
Topics: Adenine Nucleotides; Amino Acid Sequence; Animals; Atropine; Biphenyl Compounds; Cell Membrane; Dose-Response Relationship, Drug; Dynorphins; Guanine Nucleotides; Guinea Pigs; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Kinetics; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neostigmine; Neurotensin; Physostigmine; Receptors, Neurotensin; Structure-Activity Relationship | 1994 |
Vagal stimulation augments pulmonary anaphylaxis in the guinea pig lung.
Topics: Anaphylaxis; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Electric Stimulation; Guinea Pigs; Hypnotics and Sedatives; Lung; Male; Neurokinin A; Organ Size; Physostigmine; Piperidines; Trachea; Vagus Nerve; Vasoconstriction | 1995 |
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs.
Topics: Aerosols; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; Inflammation; Lung; Male; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pulmonary Circulation; Receptors, Neurokinin-2; Vascular Resistance | 1993 |
Pharmacological characterization of the contractile responses to angiotensin analogues in guinea-pig isolated longitudinal muscle of small intestine.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Tetrazoles; Tetrodotoxin | 1993 |
Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells.
Topics: Animals; Atropine; Biphenyl Compounds; Bretylium Compounds; Colon; Corticotropin-Releasing Hormone; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Glucosamine; Hexamethonium; Hormone Antagonists; Indomethacin; Intestinal Mucosa; Isoenzymes; Male; Mast Cells; Membrane Proteins; Mucins; Organ Culture Techniques; Oxamic Acid; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Restraint, Physical; RNA, Messenger; Serine Endopeptidases; Stress, Psychological; Transcription, Genetic | 1996 |
Effect of substance P and receptor antagonists on secretion of lingual lipase and amylase from rat von Ebner's gland.
Topics: Amylases; Animals; Atropine; Biphenyl Compounds; Kinetics; Lipase; Male; Neurokinin-1 Receptor Antagonists; Propranolol; Rats; Rats, Sprague-Dawley; Salivary Glands; Substance P; Time Factors; Timolol; Tongue | 1997 |
Smoke-induced airway hyperresponsiveness to inhaled wood smoke in guinea pigs: tachykininergic and cholinergic mechanisms.
Topics: Airway Resistance; Animals; Atropine; Benzamides; Biphenyl Compounds; Bronchi; Bronchial Hyperreactivity; Cholinergic Antagonists; Drug Combinations; Glycopeptides; Guinea Pigs; Male; Neprilysin; Piperidines; Protease Inhibitors; Receptors, Cholinergic; Receptors, Tachykinin; Smoke; Wood | 1998 |
Action of substance P and interaction of calcitonin gene-related peptide and substance P on the cat antral circular muscle.
Topics: Animals; Atropine; Autoradiography; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Cats; Colon; Immunohistochemistry; Muscle Contraction; Protein Binding; Pyloric Antrum; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tetrodotoxin | 1998 |
Acetylcholine and tachykinin receptor antagonists attenuate wood smoke-induced bronchoconstriction in guinea pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Atropine; Biphenyl Compounds; Bronchial Diseases; Bronchoconstriction; Bronchodilator Agents; Cholinergic Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neprilysin; Receptors, Tachykinin; Smoke; Wood | 1998 |
Pharmacological evidence that neuropeptides mediate part of the actions of scorpion venom on the guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoindoles; Muscarinic Antagonists; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Neuropeptides; Scorpion Venoms; Stereoisomerism; Substance P | 1999 |
Central injections of capsaicin cause antidiuresis mediated through neurokinin-1 receptors in rat hypothalamus and vasopressin release.
Topics: Acetylcholine; Anesthesia; Animals; Atropine; Binding Sites; Biphenyl Compounds; Capsaicin; Diuresis; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Injections, Intraventricular; Male; Microdialysis; Phenoxybenzamine; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Supraoptic Nucleus; Time Factors; Timolol; Vasopressins | 1999 |
Mechanisms of wood smoke-induced increases in nasal airway resistance and reactivity in rats.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Biphenyl Compounds; Bronchodilator Agents; Male; Nasal Cavity; Nasal Provocation Tests; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Smoke; Wood | 2002 |