atropine has been researched along with carbidopa in 15 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (carbidopa) | Trials (carbidopa) | Recent Studies (post-2010) (carbidopa) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 10 | 0 | 9 |
| 26,711 | 1,259 | 1,697 | 15 | 0 | 10 |
| 26,711 | 1,259 | 1,697 | 13 | 0 | 5 |
| 26,711 | 1,259 | 1,697 | 2,574 | 465 | 701 |
| Protein | Taxonomy | atropine (IC50) | carbidopa (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 3.55 | |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | 6.795 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 3.731 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Boggan, WO; Buckholtz, NS; Meyer, JS | 1 |
| Gaul, SL; Sweet, CS | 1 |
| Cotzias, GC; Dahl, K; Finn, BW; Mendez, JS | 1 |
| Antonaccio, MJ; Kerwin, L | 1 |
| Löscher, W | 1 |
| Maayan, ML; Sellitto, RV; Volpert, EM | 1 |
| Poddar, MK; Ray, SK | 1 |
| Antonaccio, MJ; Burrell, R; Robson, RD | 1 |
| Friedman, E; Gershon, S | 1 |
1 review(s) available for atropine and carbidopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
14 other study(ies) available for atropine and carbidopa
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Serotonergic stimulation of pituitary-adrenal activity in the mouse.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Benserazide; Carbidopa; Carbolines; Corticosterone; Cyproheptadine; Female; Fenclonine; Indoles; Metergoline; Mice; Pargyline; Phenyl Ethers; Pituitary-Adrenal System; Propylamines; Quinolines; Quipazine; Spiperone; Tryptophan | 1978 |
Antagonism of conditioned salivation in conscious dogs by antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Atropine; Carbidopa; Clonidine; Conditioning, Classical; Dogs; Drug Interactions; Female; Male; Methyldopa; Pilocarpine; Salivation | 1977 |
Rotatory behavior induced in nigra-lesioned rats by N-propylnoraporphine, apomorphine, and levodopa.
Topics: Animals; Apomorphine; Aporphines; Atropine; Behavior, Animal; Brain Injuries; Carbidopa; Dose-Response Relationship, Drug; Drug Synergism; Hydroxydopamines; Levodopa; Male; Rats; Rotation; Substantia Nigra; Time Factors | 1975 |
Centrally mediated increased reflex vagal bradycardia after L-dopa in monoamine oxidase-inhibited anesthetized dogs.
Topics: Animals; Atropine; Benserazide; Blood Pressure; Carbidopa; Dogs; Dopamine; Drug Interactions; Female; Levodopa; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Phentolamine; Pressoreceptors; Propranolol; Vagus Nerve | 1976 |
Influence of pharmacological manipulation of inhibitory and excitatory neurotransmitter systems on seizure behavior in the Mongolian gerbil.
Topics: Adrenergic alpha-Agonists; Air; Amino Acids; Animals; Anticonvulsants; Atropine; Carbidopa; Disease Models, Animal; Dopamine; Epilepsy; Female; Fenfluramine; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Male; Mice; Norepinephrine; Serotonin; Serotonin Antagonists; Species Specificity | 1985 |
Dopamine and L-dopa: inhibition of thyrotropin-stimulated thyroidal thyroxine release.
Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Bucladesine; Carbidopa; Cyclic AMP; Dopamine; Dopamine beta-Hydroxylase; Female; Levodopa; Mice; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Thyroid Gland; Thyrotropin; Thyroxine | 1986 |
Central cholinergic-dopaminergic interaction in carbaryl-induced tremor.
Topics: Animals; Atropine; Carbaryl; Carbidopa; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Levodopa; Male; Rats; Receptors, Cholinergic; Receptors, Dopamine; Tremor | 1985 |
The effects of L-dopa and alpha-methyldopa on reflexes and sympathetic nerve function.
Topics: Animals; Atropine; Barbiturates; Benserazide; Blood Pressure; Carbidopa; Carotid Arteries; Dogs; Electric Stimulation; Heart Rate; Hindlimb; Levodopa; Methyldopa; Monoamine Oxidase Inhibitors; Neurons; Perfusion; Posture; Reflex; Regional Blood Flow; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 1974 |
L-DOPA: centrally mediated emission of seminal fluid in male rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Benserazide; Carbidopa; Cyproheptadine; Dihydroxyphenylalanine; Dopamine; Ejaculation; Haloperidol; Hydrazines; Hypophysectomy; Lysergic Acid Diethylamide; Male; Melatonin; Methysergide; Norepinephrine; Phentolamine; Propranolol; Rats; Semen; Serotonin | 1972 |