atropine has been researched along with captopril in 41 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (captopril) | Trials (captopril) | Recent Studies (post-2010) (captopril) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 10,320 | 1,514 | 890 |
| Protein | Taxonomy | atropine (IC50) | captopril (IC50) |
|---|---|---|---|
| Leukotriene A-4 hydrolase | Homo sapiens (human) | 3.6 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.084 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.0173 | |
| Succinyl-diaminopimelate desuccinylase | Haemophilus influenzae Rd KW20 | 3.3 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.1004 | |
| Beta-lactamase | Pseudomonas aeruginosa | 5 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.011 | |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | 3.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (26.83) | 18.7374 |
| 1990's | 10 (24.39) | 18.2507 |
| 2000's | 8 (19.51) | 29.6817 |
| 2010's | 12 (29.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Rani, R; Rao, KS | 1 |
| Essop, R; Sareli, P; Wisenbaugh, T | 1 |
| Krell, RD; McCarthy, M | 1 |
| Del Monte, M; Omini, C; Subissi, A | 1 |
| Farmer, SG; Togo, J | 1 |
| Leonard, BE; Manning-Sayi, J | 1 |
| Chen, BB; Clougherty, PW; Geller, HS; Goll, HM; Murray, PA; Nyhan, DP | 1 |
| Beck, L; Padeken, D; Schmidt, HD | 1 |
| Bishop, VS; Hasser, EM | 1 |
| Perry, DC | 1 |
| Ashizawa, H; Fukuyama, M; Inoue, A; Lee, LC; Nakagawa, M; Nakamura, Y; Oguro, M; Sasaki, S; Takeda, K; Yoshimura, M | 1 |
| Campbell, BC; Reid, JL; Sturani, A | 1 |
| Fregly, MJ; Wilson, KM | 1 |
| Amano, H; Katsumata, M; Kubo, T; Misu, Y | 1 |
| Fregly, MJ; Greenleaf, JE; Kikta, DC | 1 |
| Gryglewski, RJ | 1 |
| Joos, GF; Kips, JC; Pauwels, RA | 1 |
| Glusa, E | 1 |
| Castagliuolo, I; Jaffer, A; Kelly, C; LaMont, JT; Letourneau, R; O'Keane, JC; Pothoulakis, C; Theoharides, TC | 1 |
| Garrison, EA; Kadowitz, PJ; Santiago, JA | 1 |
| Cordero Valeriano, JJ; Feria Rodriguez, M; Gonzalez Gonzalez, J | 1 |
| Furukawa, T; Katsuragi, T; Kushiku, K; Shibata, K; Tokunaga, R; Yamada, H | 1 |
| Adeneye, AA; Adeneye, AK; Ajagbonna, OP; Etarrh, RR; Mojiminiyi, FB; Odigie, IP; Ojobor, PD | 1 |
| Asnar, DS; Colombari, DS; De Luca, LA; de Paula, PM; Menani, JV; Roncari, CF | 1 |
| Mugabo, P; Obikeze, K; Raji, I | 1 |
| Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
1 review(s) available for atropine and captopril
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for atropine and captopril
| Article | Year |
|---|---|
Evidence of parasympathetic activity of the angiotensin converting enzyme inhibitor, captopril, in normotensive man.
Topics: Adult; Atropine; Blood Pressure; Captopril; Cold Temperature; Edrophonium; Heart Rate; Humans; Immersion; Male; Norepinephrine; Parasympathomimetics; Posture; Proline; Valsalva Maneuver | 1985 |
39 other study(ies) available for atropine and captopril
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Enhanced contractility of the rat stomach during suppression of angiotensin converting enzyme by captopril in vitro.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Atropine; Bradykinin; Captopril; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Peptidyl-Dipeptidase A; Pressure; Rats; Saralasin; Stomach; Tetrodotoxin | 1991 |
Short-term vasodilator effect of captopril in patients with severe mitral regurgitation is parasympathetically mediated.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Atropine; Captopril; Cardiac Catheterization; Hemodynamics; Humans; Mitral Valve Insufficiency; Parasympathetic Nervous System; Premedication; Rheumatic Heart Disease; Time Factors; Vasodilation | 1991 |
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan | 1991 |
Mechanism of the potentiation of neurally-induced bronchoconstriction by gallamine in the guinea-pig.
Topics: Acetylcholine; Anaphylaxis; Animals; Atropine; Bronchi; Captopril; Cholinesterase Inhibitors; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Male; Parasympatholytics; Physostigmine; Propranolol; Pyrilamine; Vagus Nerve | 1990 |
Effects of epithelium removal on relaxation of airway smooth muscle induced by vasoactive intestinal peptide and electrical field stimulation.
Topics: Animals; Atropine; Captopril; Electric Stimulation; Endopeptidases; Epithelium; Glycopeptides; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Propranolol; Protease Inhibitors; Thiorphan; Trachea; Vasoactive Intestinal Peptide | 1990 |
Studies on the nöotropic potential of some angiotensin converting enzyme inhibitors in the mouse.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atropine; Avoidance Learning; Captopril; Hypoxia; Male; Mice; Mice, Inbred BALB C; Motor Activity; Potassium Cyanide; Psychotropic Drugs; Trimethyltin Compounds | 1989 |
Combined neurohumoral block modulates pulmonary vascular P/Q relationship in conscious dogs.
Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Body Weight; Captopril; Cardiac Output; Cyclooxygenase Inhibitors; Dogs; Hemodynamics; Indomethacin; Lung; Meclofenamic Acid; Peptidyl-Dipeptidase A; Prazosin; Propranolol; Receptors, Angiotensin; Receptors, Vasopressin; Vasodilation | 1988 |
Cardiovascular effect of sparteine in anaesthetized dogs with and without blockade of cardiac autonomic nerves.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, General; Animals; Anti-Arrhythmia Agents; Atropine; Autonomic Nerve Block; Blood Pressure; Captopril; Cardiovascular System; Dogs; Heart; Injections, Intravenous; Myocardial Contraction; Reserpine; Sparteine; Stimulation, Chemical | 1986 |
Neurogenic and humoral factors maintaining arterial pressure in conscious dogs.
Topics: Animals; Arginine Vasopressin; Atropine; Blood Pressure; Captopril; Carotid Sinus; Denervation; Dogs; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Pressoreceptors; Renin-Angiotensin System; Sinus of Valsalva; Sympathetic Nervous System | 1988 |
Barrel rotation in rats induced by intracerebroventricular bradykinin antagonists.
Topics: Animals; Atropine; Bradykinin; Captopril; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Muscimol; Naloxone; Phenobarbital; Phenytoin; Posture; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Acute effects of captopril on the baroreflex of normotensive and spontaneously hypertensive rats.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Captopril; Cisterna Magna; Epoprostenol; Heart Rate; Hypertension; Hypotension; Injections; Injections, Intravenous; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Reflex; Sympathetic Nervous System; Tachycardia; Vagus Nerve | 1986 |
Angiotensin II-induced hypothermia in rats.
Topics: Angiotensin II; Animals; Atropine; Atropine Derivatives; Body Temperature Regulation; Captopril; Colon; Depression, Chemical; Female; Hypothalamus; Hypothermia; Isoproterenol; Oxygen Consumption; Parasympatholytics; Propranolol; Rats; Rats, Inbred Strains; Skin Temperature; Tail; Time Factors; Vasodilation | 1985 |
Further studies on vasopressin-induced pressor responses to kainic acid injected into the nucleus tractus solitarii of the rat.
Topics: Animals; Atropine; Blood Pressure; Captopril; Heart Rate; Injections; Kainic Acid; Male; Mecamylamine; Medulla Oblongata; Radioimmunoassay; Rats; Rats, Inbred Strains; Vasopressins | 1985 |
Bethanechol-induced water intake in rats: possible mechanisms of induction.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Captopril; Dose-Response Relationship, Drug; Drinking Behavior; Female; Isoproterenol; Potassium; Propranolol; Rats; Rats, Inbred Strains; Sodium; Urine | 1982 |
[Mechanisms regulating the release of deaggregating prostanoids].
Topics: Adrenergic beta-Antagonists; Almitrine; Angiotensins; Animals; Arachidonic Acids; Aspirin; Atropine; Captopril; Cats; Cells, Cultured; Choline; Drug Interactions; Epoprostenol; Female; Indomethacin; Male; Piperazines; Platelet Aggregation; Prostaglandins; Prostaglandins E; Saralasin; Stimulation, Chemical | 1982 |
In vivo characterization of the tachykinin receptors involved in the direct and indirect bronchoconstrictor effect of tachykinins in two inbred rat strains.
Topics: Airway Resistance; Animals; Atropine; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Methysergide; Neurokinin A; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Serotonin; Substance P; Thiorphan | 1994 |
Desulfated hirugen (hirudin 54-65) induces endothelium-dependent relaxation of porcine pulmonary arteries.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Arginine; Atropine; Bradykinin; Calcium; Captopril; Cyclic GMP; Dinoprost; Endothelium, Vascular; Hirudins; Histamine; Indomethacin; Ketanserin; Methiothepin; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptide Fragments; Phentolamine; Pulmonary Artery; Swine; Vasodilation | 1994 |
Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum.
Topics: Animals; Atropine; Bacterial Toxins; Captopril; Enterotoxins; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Intestinal Mucosa; Lidocaine; Male; Mast Cells; Microscopy, Electron; Neural Inhibition; Neurons; Rats; Rats, Wistar | 1994 |
Analysis of responses to bradykinin: effects of Hoe-140 in the hindquarters vascular bed of the cat.
Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Bradykinin; Captopril; Cats; Cyclooxygenase Inhibitors; Enalaprilat; Female; Glyburide; Hindlimb; Male | 1994 |
Autonomic mediation of short-term cardiovascular oscillations after acute hemorrhage in conscious rats.
Topics: Acute Disease; Animals; Atropine; Autonomic Nervous System; Blood Pressure; Captopril; Diastole; Electrocardiography; Heart Rate; Male; Prazosin; Propranolol; Rats; Systole | 1995 |
Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high-frequency preganglionic stimulation at the canine cardiac sympathetic ganglia.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Atropine; Blotting, Northern; Captopril; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Sympathetic; Gene Expression Regulation; Heart; Heart Rate; Pentolinium Tartrate; Pyridines; RNA, Messenger; Stellate Ganglion; Tetrazoles; Tissue Distribution; Up-Regulation | 2001 |
The hypotensive mechanisms for the aqueous stem bark extract of Musanga cecropioides in Sprague-Dawley rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Heart Rate; Muscarinic Antagonists; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Urticaceae | 2006 |
Involvement of central cholinergic mechanisms on sodium intake induced by gabaergic activation of the lateral parabrachial nucleus.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atropine; Captopril; Diuretics; Drinking; Eating; Furosemide; GABA Agonists; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic; Sodium Chloride | 2013 |
The contributions of muscarinic receptors and changes in plasma aldosterone levels to the anti-hypertensive effect of Tulbaghia violacea.
Topics: Aldosterone; Allium; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Captopril; Heart Rate; Hypertension; Male; Muscarine; Plant Extracts; Plethysmography; Random Allocation; Rats; Rats, Inbred SHR; Receptors, Muscarinic | 2013 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |