atropine has been researched along with buspirone in 16 studies
Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (buspirone) | Trials (buspirone) | Recent Studies (post-2010) (buspirone) |
---|---|---|---|---|---|
26,711 | 1,259 | 1,697 | 2,096 | 351 | 382 |
Protein | Taxonomy | atropine (IC50) | buspirone (IC50) |
---|---|---|---|
5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.025 | |
5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 1.75 | |
Angiotensin-converting enzyme | Homo sapiens (human) | 0.024 | |
D(2) dopamine receptor | Homo sapiens (human) | 0.323 | |
5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 2.125 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
D | Rattus norvegicus (Norway rat) | 0.12 | |
D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0266 | |
D(2) dopamine receptor | Bos taurus (cattle) | 4 | |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.077 | |
D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.286 | |
5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.016 | |
D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 2.125 | |
D(3) dopamine receptor | Homo sapiens (human) | 0.044 | |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.75 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.2055 | |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.9811 | |
Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.025 | |
Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.7 | |
Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.2666 | |
Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.03 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (6.25) | 18.7374 |
1990's | 2 (12.50) | 18.2507 |
2000's | 4 (25.00) | 29.6817 |
2010's | 9 (56.25) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Caliendo, G; Capasso, R; Ciano, A; Corvino, A; Di Vaio, P; Fiorino, F; Frecentese, F; Izzo, AA; Kędzierska, E; Kotlińska, JH; Magli, E; Massarelli, P; Orzelska-Gòrka, J; Perissutti, E; Rossi, I; Saccone, I; Santagada, V; Severino, B | 1 |
Hong, E; Meneses, A | 1 |
Oriowo, MA | 1 |
Camilleri, M; Coulie, BJ; Farrugia, G; Locke, GR; Meulemans, A; Schuurkes, JA; Szurszewski, JH; Xue, L | 1 |
Agretti, P; De Marco, G; Dimida, A; Ferrarini, E; Pinchera, A; Rodrìguez Gonzàlez, JC; Santini, F; Tonacchera, M; Vitti, P | 1 |
1 review(s) available for atropine and buspirone
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
15 other study(ies) available for atropine and buspirone
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
New 5-HT
Topics: Animals; Binding Sites; Biological Assay; Ileum; Ligands; Maze Learning; Molecular Structure; Picolines; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists | 2017 |
Effects of serotonergic compounds on associative learning.
Topics: Animals; Atropine; Buspirone; Conditioning, Operant; Ketanserin; Learning; Male; Quinazolines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Serotonin Antagonists | 1991 |
Neural inhibition in the rat lower esophageal sphincter: role of beta 3-adrenoceptor activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atropine; Buspirone; Carbachol; Electric Stimulation; Electrophysiology; Esophagogastric Junction; Ethanolamines; Male; Muscle Relaxation; Neural Inhibition; Nitric Oxide Synthase; Oxidopamine; Propranolol; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Serotonin Receptor Agonists; Tetrodotoxin; Vasoconstrictor Agents | 1998 |
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.
Topics: Animals; Atropine; Bethanechol; Buspirone; Gastric Fundus; Male; Mice; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Reproducibility of Results; Serous Membrane; Signal Transduction; Sumatriptan; Ultrasonography | 2006 |
Study of potential inhibitors of thyroid iodide uptake by using CHO cells stably expressing the human sodium/iodide symporter (hNIS) protein.
Topics: 14-alpha Demethylase Inhibitors; Amphotericin B; Animals; Anti-Allergic Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Atropine; Biotin; Buspirone; CHO Cells; Cricetinae; Cricetulus; Econazole; Humans; Hydrocortisone; Iodides; Metronidazole; Muscarinic Antagonists; Papaverine; Perchlorates; Phosphodiesterase Inhibitors; Promethazine; Serotonin Receptor Agonists; Sulfadiazine; Symporters; Thiocyanates; Thyroid Gland | 2011 |