Page last updated: 2024-09-05

atropine and bupivacaine

atropine has been researched along with bupivacaine in 26 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(bupivacaine)
Trials
(bupivacaine)
Recent Studies (post-2010) (bupivacaine)
26,7111,2591,69712,9684,8433,530

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's7 (26.92)18.2507
2000's7 (26.92)29.6817
2010's6 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Edwards, AE; Ferguson, BJ; Gower, DE; Smith, CJ; Williams, CP1
Guerrero, S; Hernandez, D; Morales, M1
Aasly, J; Fredriksen, T; Sjaastad, O; Wysocka Bakowska, MM1
Kasten, GW; Martin, ST1
Ghoneim, MM; Pandya, H1
Ikeogu, MO; Nolte, H; Virneberg, H1
Huang, EY; Hung, CR1
Bassoul, B; Bruelle, P; de La Coussaye, JE; Desch, G; Eledjam, JJ; Lefrant, JY; Peray, PA; Sassine, A1
Karemaker, JM; Ros, HH; Scheffer, GJ; TenVoorde, BJ1
Bassoul, B; Bruelle, P; de La Coussaye, JE; Desch, G; Eledjam, JJ; Gagnol, JP; Lefrant, JY; Peray, P; Sassine, A1
Chemtob, S; Deng, XF; Mulay, S; Varma, DR1
Kimura, I; Nojima, H; Takada, M1
Adachi, Y; Higuchi, H; Hirata, J; Kazama, T1
Finco, G; Ischia, S; Luzzani, A; Polati, E; Schweiger, V1
Neema, PK; Rathod, RC; Sethuraman, M1
Anbarasan, I; Gander, S; Jain, K; Makkar, JK; Yadanappudi, S1
Imai, K; Kayashima, K; Kinoshita, Y; Yoshino, H1
Dokuzeylul, B; Gunay, Z; Karacam, E; Kirşan, İ; Toydemir, TS; Yilmaz, ÖT1
Lee, D; Nelson, M; Reda, L; Reens, A1

Trials

2 trial(s) available for atropine and bupivacaine

ArticleYear
Influence of lumbosacral cerebrospinal fluid density, velocity, and volume on extent and duration of plain bupivacaine spinal anesthesia.
    Anesthesiology, 2004, Volume: 100, Issue:1

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Atropine; Bupivacaine; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure; Depression, Chemical; Female; Hemodynamics; Humans; Magnetic Resonance Imaging; Male; Muscarinic Antagonists

2004
Two doses of spinal bupivacaine for caesarean delivery in severe preeclampsia: a pilot study.
    International journal of obstetric anesthesia, 2012, Volume: 21, Issue:2

    Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Adult; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Anti-Arrhythmia Agents; Atropine; Bradycardia; Bupivacaine; Cesarean Section; Dose-Response Relationship, Drug; Ephedrine; Female; Fentanyl; Humans; Hypotension; Phenylephrine; Pilot Projects; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Young Adult

2012

Other Studies

24 other study(ies) available for atropine and bupivacaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Leucocyte migration: effects of in vitro exposure to anaesthetic agents: possible potentiation of effects by adrenaline.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:6

    Topics: Adult; Anesthetics; Atropine; Bupivacaine; Cell Migration Inhibition; Cell Movement; Cell Survival; Drug Synergism; Epinephrine; Humans; Hydrocortisone; Leukocytes; Lidocaine; Lorazepam; Lymphocytes; Middle Aged; Morphine; Norepinephrine; Pancuronium; Succinylcholine; Thiopental

1992
Electrophysiological effects of bupivacaine on transitional pacemaker cells of the frog heart.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 288, Issue:1

    Topics: Action Potentials; Animals; Anura; Atropine; Bupivacaine; Heart Conduction System; In Vitro Techniques; Membrane Potentials; Synaptic Transmission; Tetrodotoxin

1987
Chronic paroxysmal hemicrania. X. On the autonomic involvement.
    Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:2

    Topics: Atropine; Autonomic Nerve Block; Autonomic Nervous System; Bupivacaine; Chronic Disease; Cornea; Female; Forehead; Hot Temperature; Humans; Indomethacin; Intraocular Pressure; Migraine Disorders; Moxisylyte; Pulse; Skin Temperature; Stellate Ganglion; Sweating; Time Factors; Tonometry, Ocular

1986
Successful cardiovascular resuscitation after massive intravenous bupivacaine overdosage in anesthetized dogs.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:5

    Topics: Animals; Apnea; Atropine; Bradycardia; Bupivacaine; Dogs; Electrocardiography; Epinephrine; Female; Heart Massage; Heart Ventricles; Male; Resuscitation; Shock; Tachycardia

1985
Plasma protein binding of bupivacaine and its interaction with other drugs in man.
    British journal of anaesthesia, 1974, Volume: 46, Issue:6

    Topics: Atropine; Binding, Competitive; Blood Proteins; Bupivacaine; Desipramine; Dialysis; Drug Interactions; Heparin; Humans; Meperidine; Phenytoin; Protein Binding; Quinidine

1974
[The behaviour of the cardiac rhythm during general and regional anaesthesia].
    Der Anaesthesist, 1973, Volume: 22, Issue:5

    Topics: Anesthesia, Inhalation; Anesthesia, Local; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atropine; Bupivacaine; Digitalis Glycosides; Drug Combinations; Drug Synergism; Electrocardiography; Halothane; Heart; Heart Conduction System; Heart Rate; Humans; Morphine; Nitrous Oxide; Preanesthetic Medication; Pulse; Scopolamine; Succinylcholine; Thiopental

1973
Role of acid back-diffusion in the formation of mucosal ulceration and its treatment with drugs in diabetic rats.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Atropine; Blood Glucose; Bupivacaine; Diabetes Mellitus, Experimental; Diffusion; Gastric Acid; Insulin; Male; Peptic Ulcer Hemorrhage; Rats; Rats, Wistar; Stomach Ulcer

1995
Mechanisms of the putative cardioprotective effect of hexamethonium in anesthetized dogs given a large dose of bupivacaine.
    Anesthesiology, 1994, Volume: 80, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Atrial Function; Atropine; Bupivacaine; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Female; Heart; Heart Atria; Heart Conduction System; Heart Diseases; Heart Rate; Hexamethonium; Hexamethonium Compounds; Male; Models, Biological; Parasympathetic Nervous System; Pentobarbital; Sodium Channels

1994
Effects of epidural analgesia and atropine on heart rate and blood pressure variability: implications for the interpretation of beat-to-beat fluctuations.
    European journal of anaesthesiology, 1994, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Atropine; Baroreflex; Blood Pressure; Bupivacaine; Electrocardiography; Heart Rate; Humans; Middle Aged; Nerve Block; Respiration; Sinoatrial Node; Sympathetic Nervous System; Vagus Nerve; Vasomotor System

1994
Lemakalim, a potassium channel agonist, reverses electrophysiological impairments induced by a large dose of bupivacaine in anaesthetized dogs.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Anesthesia, General; Animals; Atropine; Benzopyrans; Bupivacaine; Cromakalim; Dogs; Electrocardiography; Female; Heart; Heart Rate; Male; Potassium Channels; Pyrroles; Time Factors

1993
Mechanisms of the atrium-specific positive inotropic activities of quinidine- and atropine-like agents in rats.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Bupivacaine; Catecholamines; Dimethylphenylpiperazinium Iodide; Disopyramide; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stimulation, Chemical

1997
Aconitine induces bradycardia through a transmission pathway including the anterior hypothalamus in conscious mice.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:8

    Topics: Aconitine; Anesthetics, Local; Animals; Atropine; Blood Pressure; Bradycardia; Bupivacaine; Cerebral Cortex; Hypothalamus, Anterior; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Neural Pathways; Pulse; Synaptic Transmission

1997
The role of neurolytic celiac plexus block in the treatment of pancreatic cancer pain.
    Transplantation proceedings, 2008, Volume: 40, Issue:4

    Topics: Anesthetics, Local; Atropine; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Humans; Pain, Intractable; Pancreatic Neoplasms; Premedication

2008
Combined monitored anesthesia care and femoral nerve block for muscle biopsy in children with myopathies.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:7

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics, Combined; Anesthetics, Local; Atropine; Biopsy; Bupivacaine; Child, Preschool; Female; Femoral Nerve; Humans; Infant; Infant, Newborn; Intensive Care Units; Ketamine; Male; Midazolam; Monitoring, Physiologic; Muscle, Skeletal; Muscular Diseases; Nerve Block; Oxygen

2008
[Four cases of cardiac arrest during spinal anesthesia].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:10

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Atropine; Blood Volume; Bupivacaine; Heart Arrest; Humans; Intraoperative Complications; Male; Middle Aged; Young Adult

2012
Effects of surgical wound infiltration with bupivacaine on postoperative analgesia in cats undergoing bilateral mastectomy.
    The Journal of veterinary medical science, 2014, Volume: 76, Issue:12

    Topics: Anesthesia, Local; Animals; Atropine; Bupivacaine; Cat Diseases; Cats; Female; Humans; Isoflurane; Mammary Neoplasms, Animal; Mastectomy; Pain Measurement; Pain, Postoperative; Propofol; Surveys and Questionnaires; Time Factors

2014
Profound Prolonged Bradycardia and Hypotension after Interscalene Brachial Plexus Block with Bupivacaine.
    The Journal of emergency medicine, 2018, Volume: 54, Issue:3

    Topics: Aged; Anesthetics, Local; Atropine; Brachial Plexus Block; Bradycardia; Bupivacaine; Emergency Service, Hospital; Epinephrine; Humans; Hypotension; Lidocaine; Male; Parasympatholytics

2018