atropine has been researched along with bumetanide in 30 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (bumetanide) | Trials (bumetanide) | Recent Studies (post-2010) (bumetanide) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 2,033 | 150 | 354 |
| Protein | Taxonomy | atropine (IC50) | bumetanide (IC50) |
|---|---|---|---|
| Solute carrier family 12 member 2 | Homo sapiens (human) | 0.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.33) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 10 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Barker, S; Curry, M; Martinez, JR; Seagrave, JC | 1 |
| Bindslev, N; Winding, B | 2 |
| Gaginella, TS; Kachur, JF; Tien, XY; Wallace, LJ; Won-Kim, S | 1 |
| Levin, RJ; Young, A | 1 |
| Gaginella, TS; Kachur, JF; Phillips, GS | 1 |
| Dissing, S; Nauntofte, B | 1 |
| Carey, HV; Cooke, HJ | 1 |
| Saga, K; Sato, K | 1 |
| Dharmsathaphorn, K; Pandol, SJ | 1 |
| Saga, K; Sato, F; Sato, K | 1 |
| Barrett, KE; Bidinger, J; Cooke, HJ; Javed, NH; Wang, YZ | 1 |
| Hansen, MB | 1 |
| Demedts, MG; Pype, JL; Verleden, GM | 1 |
| Hosoda, Y; Iwanaga, T; Kuwahara, A; Winarto, A | 1 |
| Manabe, K; Morishima, S; Okada, Y; Shimizu, T | 1 |
| Karaki, S; Kuwahara, A | 1 |
1 review(s) available for atropine and bumetanide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
29 other study(ies) available for atropine and bumetanide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
The effect of NH4Cl on Rb+ fluxes in resting and stimulated rat submandibular acinar cells.
Topics: Acetylcholine; Ammonia; Ammonium Chloride; Animals; Atropine; Bumetanide; Butyrates; Butyric Acid; Charybdotoxin; Dimethylamines; Hydrogen-Ion Concentration; Male; Methylamines; Ouabain; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Scorpion Venoms; Submandibular Gland | 1992 |
Characterization of a muscarinic receptor controlling Cl- secretion in hen trachea.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bumetanide; Calcium Channels; Chickens; Chlorides; Dicyclomine; Female; In Vitro Techniques; Ion Channels; Kinetics; Mucous Membrane; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Characterization of Ile,Ser-bradykinin-induced changes in short-circuit current across rat colon.
Topics: Animals; Atropine; Bradykinin; Bumetanide; Chlorides; Colon; Culture Techniques; Electrophysiology; Ion Channels; Male; Rats; Rats, Inbred Strains; Tetrodotoxin | 1990 |
Segmental heterogeneity of rat colonic electrogenic secretion in response to the bacterial enterotoxin Escherichia coli STa in vitro.
Topics: Animals; Atropine; Bacterial Toxins; Bumetanide; Chlorides; Colon; Dose-Response Relationship, Drug; Enterotoxins; Escherichia coli Proteins; Intestinal Mucosa; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Tetrodotoxin | 1991 |
Neuromodulation of guinea pig intestinal electrolyte transport by cholecystokinin octapeptide.
Topics: Animals; Atropine; Biological Transport; Bumetanide; Calcium; Culture Media; Dose-Response Relationship, Drug; Electrolytes; Electrophysiology; Guinea Pigs; Ileum; Intestinal Mucosa; Intestines; Male; Proglumide; Receptors, Cholecystokinin; Sincalide; Tetrodotoxin | 1991 |
Na+ transport properties of isolated rat parotid acini.
Topics: Acetazolamide; Amiloride; Animals; Atropine; Biological Transport, Active; Bumetanide; Carbachol; Chlorides; Fluoresceins; Fluorescent Dyes; Furosemide; In Vitro Techniques; Kinetics; Male; Ouabain; Parotid Gland; Rats; Rats, Inbred Strains; Sodium | 1990 |
Thyrotropin-releasing hormone (TRH) evokes chloride secretion via cholinergic pathways in the guinea-pig ileum.
Topics: Animals; Atropine; Bumetanide; Chlorides; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Mecamylamine; Neural Pathways; Parasympathetic Nervous System; Serotonin; Tetrodotoxin; Thyrotropin-Releasing Hormone | 1989 |
Electron probe X-ray microanalysis of cellular ions in the eccrine secretory coil cells during methacholine stimulation.
Topics: Animals; Atropine; Biological Transport; Bumetanide; Calcium; Cell Nucleus; Cytoplasm; Cytoplasmic Granules; Eccrine Glands; Electrolytes; Electron Probe Microanalysis; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Spectrum Analysis; Sweat; Sweat Glands | 1989 |
Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line.
Topics: Alprostadil; Atropine; Barium; Bumetanide; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane; Chlorides; Colon; Cyclic AMP; Drug Synergism; Electric Conductivity; Epithelium; Humans; Kinetics; Potassium; Vasoactive Intestinal Peptide | 1986 |
K+ efflux from the monkey eccrine secretory coil during the transient of stimulation with agonists.
Topics: Animals; Atropine; Bumetanide; Calcimycin; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Methods; Ouabain; Phenylephrine; Physostigmine; Potassium; Sweat Glands | 1988 |
Enhanced tissue responsiveness in colonic ion transport of cow's milk-sensitized guinea pigs.
Topics: Animals; Atropine; Bumetanide; Cattle; Cells, Cultured; Chlorides; Colon; Dicarboxylic Acids; Electric Stimulation; Guinea Pigs; Histamine Release; Immunization; Intestinal Mucosa; Ion Transport; Lactoglobulins; Leukotriene D4; Male; Mast Cells; Milk; Piroxicam; Tetrodotoxin | 1994 |
ICS 205-930 reduces 5-methoxytryptamine-induced short-circuit current in stripped pig jejunum.
Topics: 5-Methoxytryptamine; Animals; Atropine; Bumetanide; Drug Interactions; Electrophysiology; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indoles; Jejunum; Kinetics; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Swine; Tetrodotoxin; Theophylline; Tropisetron | 1994 |
Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro.
Topics: Animals; Arginine; Atropine; Bumetanide; Chymotrypsin; Drug Therapy, Combination; Electric Stimulation; Female; Furosemide; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Nedocromil; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Premedication; Propranolol; Trachea; Vasoactive Intestinal Peptide | 1994 |
Desensitization and reactivation of ACh-regulated exocrine secretion in hen tracheal epithelium.
Topics: Acetylcholine; Animals; Atropine; Bumetanide; Chickens; Chlorides; Electric Conductivity; Epithelium; Exocrine Glands; Female; Osmolar Concentration; Signal Transduction; Trachea | 1993 |
Mode of action of ANG II on ion transport in guinea pig distal colon.
Topics: Angiotensin II; Animals; Atropine; Biological Transport; Bumetanide; Chlorides; Colon; Dinoprostone; Electric Conductivity; Guinea Pigs; Hydrazines; Immunohistochemistry; Ions; Male; Neurokinin-1 Receptor Antagonists; Oxazepines; Prostaglandin Antagonists; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrodotoxin | 2000 |
Regulatory volume increase after secretory volume decrease in colonic epithelial cells under muscarinic stimulation.
Topics: Animals; Atropine; Bumetanide; Calcium; Carbachol; Cell Line; Cell Size; Cells, Cultured; Colon; Egtazic Acid; Epithelial Cells; Female; Guinea Pigs; Humans; Microscopy, Confocal; Muscarinic Agonists; Niflumic Acid; Patch-Clamp Techniques; Sodium-Potassium-Chloride Symporters | 2004 |
Propionate-induced epithelial K(+) and Cl(-)/HCO3(-) secretion and free fatty acid receptor 2 (FFA2, GPR43) expression in the guinea pig distal colon.
Topics: Animals; Atropine; Bicarbonates; Bumetanide; Capsaicin; Chlorides; Colon; Dioxanes; Enteroendocrine Cells; Fatty Acids, Nonesterified; Granisetron; Guinea Pigs; Hexamethonium; Intestinal Mucosa; Male; omega-Conotoxin GVIA; Piperidines; Potassium; Propionates; Pyridoxal Phosphate; Receptors, G-Protein-Coupled; Serous Membrane; Suramin; Tetrodotoxin | 2011 |