Page last updated: 2024-09-05

atropine and arecoline

atropine has been researched along with arecoline in 103 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(arecoline)
Trials
(arecoline)
Recent Studies (post-2010) (arecoline)
26,7111,2591,6971,11020271

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)arecoline (IC50)
Muscarinic acetylcholine receptor M2Homo sapiens (human)3.6
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)1.011
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.963
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.963
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.963
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.9163
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.115

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-199068 (66.02)18.7374
1990's18 (17.48)18.2507
2000's10 (9.71)29.6817
2010's6 (5.83)24.3611
2020's1 (0.97)2.80

Authors

AuthorsStudies
Baker, R; Book, T; Freedman, SB; Marwood, RS; Patel, S; Reeve, AJ; Saunders, J; Street, LJ; Willson, T1
Baker, R; Freedman, SB; Gibbons, TL; Kneen, CO; MacLeod, AM; Merchant, K; Patel, S; Saunders, J; Showell, GA1
Baker, R; Book, T; Freedman, SB; Herbert, RH; Kneen, CO; MacLeod, AM; Merchant, KJ; Saunders, J; Showell, GA; Street, LJ1
Baker, R; Cassidy, M; Freedman, SB; Harley, EA; Iversen, LL; Kneen, C; MacLeod, AM; Merchant, KJ; Saunders, J; Snow, RJ1
Baker, R; Freedman, SB; MacLeod, AM; Merchant, KJ; Patel, S; Roe, M; Saunders, J1
Baker, R; Freedman, SB; Harley, EA; Saunders, J; Showell, GA; Snow, RJ1
Andrews, PR; Craik, DJ; Martin, JL1
Go, ML; Sim, MK; Xu, R1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Kuhar, MJ; Rommelspacher, H1
Dodson, RA; Johnson, WE1
Gala, RR; Lawson, DM1
Dinnendahl, V; Stock, K1
Andreas, K; Lehmann, K1
Abood, LG; Aronstam, R; Baumgold, J1
Dudar, JD; Hadházy, P; Szerb, JC1
Bohuschke, N; Philippu, A1
Houser, VP1
Iwamoto, ET; Loh, HH; Way, EL2
Gala, RR; Subramanian, MG2
Beattie, MS; Berntson, GG; Walker, JM1
Haefely, W; Jalfre, M; Ruch-Monachon, MA1
Maayani, S; Sokolovsky, M; Treister, G1
Contreras, E; Quijada, L; Tamayo, L1
Lambrecht, G; Mutschler, E2
Elliott, CJ; Hastwell, C; Stow, RA1
Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E; Tacke, R1
DeGeorge, JJ; Nariai, T; Rapoport, SI; Williams, WM; Yamazaki, S1
Costa, G; De Pasquale, R; Princi, P; Saija, A1
Cassone, MC; Molinengo, L; Orsetti, M1
Lambert, DG; Nahorski, SR1
Araki, Y; Furuno, K; Gomita, Y; Suemaru, K1
Ghataorre, AS; Lambert, DG; Nahorski, SR1
Speckmann, EJ; Walden, J; Witte, OW1
Molinengo, L; Orsetti, M1
Jamal, OS; Overstreet, DH1
Alvarado-Garcia, R; Lee, MA; Witkin, JM; Witkin, KM1
Blozovski, D; Duméry, V1
Elaev, NR; Evdokimov, LD; Ryzhakov, AV1
Gala, RR; Haisenleder, DJ1
Elaev, NR; Ryzhakov, AV1
Konno, F; Takayanagi, I1
Gothoni, P1
Fitton, AG; Gourine, VN; Tsaryuk, VV1
Fukuda, T; Gomita, Y; Ichimaru, Y; Moriyama, M1
Krstić, MK1
Bartholini, G; Keller, HH; Pletscher, A1
György, L; Phan, DV2
Snyder, SH; Yamamura, HI1
Fernando, MM; Grove, DJ1
Olenev, SN1
Krip, G; Vázquez, J1
Hamilton, TC1
Nose, T; Takemoto, H1
Doi, T; Ikeda, M; Nishikawa, T; Tsujimoto, A1
Beleslin, DB; Grabović, L; Radmanović, BZ1
Andreas, K; Stehl, G1
Costall, B; Naylor, RJ; Olley, JE1
Aitken, ID; Parry, SH1
Andreas, K; Eichmann, H; Legler, R; Wagner, U1
Rosecrans, JA; Schechter, MD1
Fong, KT; McFarlane, JE1
Rozhkova, EK1
Berntson, GG; Leibowitz, SF1
Leaf, RC; Wnek, DJ1
Eldefrawi, ME; Schleifer, LA1
Brase, DA; Loh, HH; Tseng, LF; Way, EL1
Carter, MK; May, DG1
Feĭgman, EE; Skliarov, AI; Voronov, IB1
Gibson, GE; Pelmas, CJ; Peterson, C1
Andreas, K; Fischer, HD; Schmidt, J1
Baissat, J; Chassaing, C; Duchêne-Marullaz, P; Dureng, G1
Kishi, K; Kobayashi, F1
Huger, FP; Smith, CP1
Barclay, L; Blass, J; Gibson, G1
Glick, SD; Guido, RA1
Bai, D; Sattelle, DB1
Classen, M; Schaffer, K; Schepp, W; Schusdziarra, V; Wegner, U; Weigert, N1
Barzaghi, F; Bonetti, C; Cesana, R; Fortin, M; Galliani, G; Hunt, P; Maggioni, A; Nencioni, A; Parini, C; Toja, E1
Farlow, MR; Lahiri, DK1
Elazar, Z; Ganchrow, D; Paz, M1
Hahn, LJ; Jeng, JH; Kuo, MY; Kuo, YS; Tsai, CL; Yang, PJ1
Guarente, L; Hawdon, J; Hotez, P; Perregaux, M; Ruvkun, G; Tissenbaum, HA1
Chang, KC; Chen, CL; Chiu, TH; Yang, YR1
Malomough, A; Naumenko, N; Nikolsky, E; Urazaev, A; Vyskocil, F1
Feinmark, SJ; Gor, Y; Kehoe, J; Schwartz, JH; Steel, DJ; Tieman, TL1
Patil, PN; Stearns, R1
Drake, MJ; Gillespie, JI; Harvey, IJ2
KHARAUZOV, NA1
Dussor, GO; Flores, CM; Hargreaves, KM; Helesic, G1
Crittenden, EL; García, DM; González, A1
Chen, LB; Liu, CY; Liu, KJ; Wang, PS; Xie, DP; Zhang, CL1
Chatterji, U; Chaudhuri-Sengupta, S; Dasgupta, R; Maiti, BR; Nag, D; Nag, TC1
Gengin, MT; Lobzina, ES; Pavlova, OV; Solov'ev, VB; Solov'eva, OV1
Al-Sabah, S; Challiss, RA; Holdich, J; Krasel, C; Mahaut-Smith, MP; Markovic, D; Mistry, R1
Cui, WY; Long, CL; Pan, ZY; Wang, H; Zhang, YF; Zhao, RJ1
Cao, L; Chen, Q; Chen, Z; Jiang, Z; Zhang, J1

Reviews

1 review(s) available for atropine and arecoline

ArticleYear
The role of the cholinergic system in thiamin deficiency.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylcholine; Aging; Animals; Arecoline; Atropine; Behavior, Animal; Brain; Diet; Electrophysiology; Ganglia, Sympathetic; Humans; Male; Oxythiamine; Parasympathetic Nervous System; Physostigmine; Pyrithiamine; Pyruvates; Pyruvic Acid; Rats; Synapses; Thiamine Deficiency; Tissue Distribution

1982

Other Studies

102 other study(ies) available for atropine and arecoline

ArticleYear
Synthesis and muscarinic activity of quinuclidinyl- and (1-azanorbornyl)pyrazine derivatives.
    Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

    Topics: Animals; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Norbornanes; Parasympathomimetics; Pyrazines; Quinuclidines; Rats; Receptors, Muscarinic; Structure-Activity Relationship

1992
Tetrahydropyridyloxadiazoles: semirigid muscarinic ligands.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Crystallization; Hydrogen Bonding; Male; Molecular Conformation; Molecular Structure; Oxadiazoles; Parasympathomimetics; Pyridines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship; Thermodynamics; X-Ray Diffraction

1991
Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:10

    Topics: Animals; Cerebral Cortex; In Vitro Techniques; Ligands; Oxadiazoles; Parasympathomimetics; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

1990
Novel quinuclidine-based ligands for the muscarinic cholinergic receptor.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:4

    Topics: Animals; Binding Sites; Cerebral Cortex; Computer Simulation; Kinetics; Models, Chemical; Oxadiazoles; Quinuclidines; Rats; Receptors, Muscarinic; Structure-Activity Relationship

1990
Synthesis and muscarinic activities of 1,2,4-thiadiazoles.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Binding, Competitive; Cerebral Cortex; Indicators and Reagents; Kinetics; Ligands; Models, Molecular; Molecular Structure; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiadiazoles; X-Ray Diffraction

1990
2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Dioxolanes; Dioxoles; In Vitro Techniques; Inositol Phosphates; Male; Molecular Conformation; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Spiro Compounds; Structure-Activity Relationship

1988
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists.
    Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17

    Topics: Animals; Aorta; Binding, Competitive; Drug Design; Escape Reaction; In Vitro Techniques; Male; Maze Learning; Mice; Models, Molecular; Molecular Structure; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylscopolamine; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Structure-Activity Relationship; Tropanes

1998
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 291, Issue:1

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Axons; Benzilates; Hippocampus; Oxotremorine; Parasympathetic Nervous System; Parasympathomimetics; Quinuclidines; Rats; Receptors, Cholinergic; Scopolamine; Septal Nuclei; Septum Pellucidum; Synaptic Transmission

1975
Effects of ethanol, arecoline, atropine and nicotine, alone and in various combinations, on rat cerebellar cyclic guanosine 3',5-monophosphate.
    Neuropharmacology, 1979, Volume: 18, Issue:11

    Topics: Animals; Arecoline; Atropine; Cerebellum; Cyclic GMP; Drug Interactions; Ethanol; Male; Nicotine; Rats

1979
The influence of adrenergic, dopaminergic, cholinergic and serotoninergic drugs on plasma prolactin levels in ovariectomized, estrogen-treated rats.
    Endocrinology, 1975, Volume: 96, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Arecoline; Atropine; Castration; Clonidine; Dibenzothiepins; Dopamine; Estradiol; Female; Isoproterenol; Mecamylamine; Nicotine; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Piperazines; Prolactin; Rats; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Sulfides

1975
Effects of arecoline and cholinesterase inhibitors on cyclic guanosine 3',5'-monophosphate and adenosine 3'.5'-monophosphate in mouse brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 290, Issue:2-3

    Topics: Animals; Arecoline; Atropine; Brain; Brain Chemistry; Cerebellum; Cholinesterase Inhibitors; Cyclic AMP; Cyclic GMP; Diazepam; Male; Mice; MSH Release-Inhibiting Hormone; Paraoxon; Physostigmine

1975
[Pharmacological modification of evoked caudate nucleus potentials].
    Acta biologica et medica Germanica, 1979, Volume: 38, Issue:9

    Topics: Animals; Apomorphine; Arecoline; Atropine; Autonomic Agents; Caudate Nucleus; Chlorpromazine; Electric Stimulation; Evoked Potentials; Female; Gallamine Triethiodide; Putamen; Rats; Substantia Nigra

1979
Studies on the relationship of binding affinity to psychoactive and anticholingergic potency of a group of psychotomimetic glycolates.
    Brain research, 1977, Mar-25, Volume: 124, Issue:2

    Topics: Animals; Arecoline; Atropine; Binding Sites; Binding, Competitive; Brain; Carbachol; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Glycolates; Hallucinogens; Kinetics; Male; Parasympatholytics; Phosphatidylserines; Quinuclidines; Rats; Receptors, Drug; Scopolamine; Stereoisomerism; Structure-Activity Relationship

1977
Release of [3H]acetylcholine from rat hippocampal slices: effect of septal lesion and of graded concentrations of muscarnic agonists and antagonists.
    Brain research, 1977, Jun-10, Volume: 128, Issue:2

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Carbachol; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mecamylamine; Oxotremorine; Pilocarpine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Septum Pellucidum

1977
Hypothalamic superfusion with muscarinic drugs: their effects on pressor responses to hypothalamic stimulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 292, Issue:1

    Topics: Alkaloids; Amanitins; Animals; Arecoline; Atropine; Atropine Derivatives; Blood Pressure; Cats; Electric Stimulation; Female; Hexamethonium Compounds; Hypothalamus; Hypothalamus, Posterior; Male; Oxotremorine; Parasympathomimetics; Perfusion; Pyrrolidines; Quaternary Ammonium Compounds

1976
Modulation of the aversive qualities of shock through a central inhibitory cholinergic system in the rat.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:5

    Topics: Animals; Arecoline; Atropine; Avoidance Learning; Carbachol; Electroshock; Male; Neostigmine; Nicotine; Parasympathetic Nervous System; Pilocarpine; Rats; Scopolamine; Time Factors

1976
Circling behavior in rats with 6-hydroxydopamine or electrolytic nigral lesions,.
    European journal of pharmacology, 1976, Volume: 37, Issue:2

    Topics: Animals; Arecoline; Atropine; Behavior; Biogenic Amines; Brain Chemistry; Catalepsy; Dopamine; Humans; Hydroxydopamines; Male; Rats; Receptors, Drug; Stereotyped Behavior; Substantia Nigra

1976
Dopaminergic-cholinergic interactions in naloxone-induced circling in morphine-dependent rats with nigral lesions.
    European journal of pharmacology, 1976, Volume: 38, Issue:1

    Topics: Animals; Apomorphine; Arecoline; Atropine; Behavior; Dopamine; Humans; Hydroxydopamines; Male; Morphine Dependence; Naloxone; Parasympathetic Nervous System; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra

1976
Further studies on the effects of adrenergic, serotonergic and cholinergic drugs on the afternoon surge of plasma prolactin in ovariectomized, estrogen-treated rats.
    Neuroendocrinology, 1976, Volume: 22, Issue:3

    Topics: Animals; Arecoline; Atropine; Castration; Circadian Rhythm; Cyproheptadine; Estradiol; Female; Methysergide; Phenoxybenzamine; Prolactin; Propranolol; Rats

1976
Effects of nicotinic and muscarinic compounds on biting attack in the cat.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:3

    Topics: Aggression; Animals; Arecoline; Atropine; Cats; Female; Hexamethonium Compounds; Humans; Male; Nicotine; Time Factors

1976
Drugs and PGO waves in the lateral geniculate body of the curarized cat. IV. The effects of acetylcholine, GABA and benzodiazepines on PGO wave activity.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 219, Issue:2

    Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Acetylcholine; Aminobutyrates; Animals; Arecoline; Atropine; Benzodiazepines; Cats; Chlordiazepoxide; Electroencephalography; gamma-Aminobutyric Acid; Geniculate Bodies; Mecamylamine; Nicotine; Occipital Lobe; Physostigmine; Pons

1976
A rapid method for measuring miotic activity of drugs in the intact mouse eye.
    Investigative ophthalmology, 1975, Volume: 14, Issue:2

    Topics: Amides; Animals; Arecoline; Atropine; Cholinesterase Inhibitors; Cyclopentanes; Dimethylamines; Drug Interactions; Lighting; Methods; Mice; Microscopy; Miotics; Mydriatics; Parasympathomimetics; Phencyclidine; Phenylacetates; Pupil; Pyridines; Time Factors

1975
Sensitivity changes to morphine and other drugs induced by cholinergic blockade.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 214, Issue:2

    Topics: Amphetamine; Analgesics; Animals; Arecoline; Atropine; Drug Tolerance; Female; Hexobarbital; Humans; Mice; Morphine; Parasympatholytics; Pentylenetetrazole; Reserpine; Sleep; Substance Withdrawal Syndrome; Time Factors

1975
Quaternary isoarecoline: a potent muscarine-like and nicotine-like acting agonist.
    Experientia, 1975, Nov-15, Volume: 31, Issue:11

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Cold Temperature; Dose-Response Relationship, Drug; Ganglionic Stimulants; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Muscle Contraction; Parasympathomimetics; Procaine

1975
The influence of cholinergic, adrenergic, and serotonergic drugs on the afternoon surge of plasma prolactin in ovariectomized, estrogen-treated rats.
    Endocrinology, 1976, Volume: 98, Issue:4

    Topics: Animals; Arecoline; Atropine; Carbachol; Castration; Circadian Rhythm; Estradiol; Female; Methysergide; Nicotine; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Prolactin; Propranolol; Rats; Sympathomimetics; Time Factors

1976
Cholinergic interneurons in the feeding system of the pond snail Lymnaea stagnalis. I. Cholinergic receptors on feeding neurons.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1992, May-29, Volume: 336, Issue:1277

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Digestive System; Eating; Ganglia; Hexamethonium; Hexamethonium Compounds; Interneurons; Lymnaea; Quaternary Ammonium Compounds; Receptors, Cholinergic

1992
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihypertensive Agents; Aorta, Abdominal; Arecoline; Atropine; Diamines; Endothelium, Vascular; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic

1991
Arecoline-stimulated brain incorporation of intravenously administered fatty acids in unanesthetized rats.
    Journal of neurochemistry, 1991, Volume: 56, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arecoline; Atropine; Autoradiography; Brain; Carbon Radioisotopes; Docosahexaenoic Acids; Fatty Acids; Infusions, Intravenous; Male; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred F344

1991
Arecoline, but not haloperidol, induces changes in the permeability of the blood-brain barrier in the rat.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:2

    Topics: Aminoisobutyric Acids; Animals; Arecoline; Atropine; Blood Volume; Blood-Brain Barrier; Haloperidol; Kinetics; Male; Permeability; Rats; Rats, Inbred Strains; Regional Blood Flow

1990
Effects of combinations of arecoline and atropine on mouse motor activity.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:1

    Topics: Animals; Arecoline; Atropine; Drug Interactions; Mice; Mice, Inbred Strains; Motor Activity; Reference Values

1990
Muscarinic-receptor-mediated changes in intracellular Ca2+ and inositol 1,4,5-trisphosphate mass in a human neuroblastoma cell line, SH-SY5Y.
    The Biochemical journal, 1990, Jan-15, Volume: 265, Issue:2

    Topics: Arecoline; Atropine; Benzofurans; Calcium; Carbachol; Cell Line; Fluorescent Dyes; Fura-2; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Manganese; Muscarine; Neuroblastoma; Receptors, Muscarinic; Tumor Cells, Cultured

1990
Nicotine-induced tail-tremor and drug effects.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: Animals; Arecoline; Atropine; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Nicotine; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine; Tail; Tremor

1989
Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1.
    European journal of pharmacology, 1989, Jun-08, Volume: 165, Issue:1

    Topics: Arecoline; Atropine; Carbachol; Cell Membrane; Humans; Neuroblastoma; Piperidines; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured

1989
Acetylcholine responses of identified neurons in Helix pomatia--II. Pharmacological properties of acetylcholine responses.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 80, Issue:1

    Topics: Acetylcholine; Animals; Anthracenes; Arecoline; Atropine; Electric Conductivity; Helix, Snails; Hexamethonium Compounds; In Vitro Techniques; Membrane Potentials; Neostigmine; Neurons; Tubocurarine

1985
Dose versus survival time curves in the evaluation of 'prompt' and 'delayed' acute toxicities.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:1

    Topics: Animals; Arecoline; Atropine; Female; Isoflurophate; Lethal Dose 50; Mice; Nicotine; Pilocarpine

1986
Behavioural tolerance to arecoline in rats: cross-tolerance to oxotremorine and prevention by pretreatment with atropine.
    Psychopharmacology, 1986, Volume: 89, Issue:1

    Topics: Animals; Arecoline; Atropine; Conditioning, Operant; Drug Tolerance; Female; Oxotremorine; Rats; Rats, Inbred Strains; Reinforcement Schedule

1986
Nonmuscarinic neurotoxicity of oxotremorine.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Arecoline; Atropine; Atropine Derivatives; Benactyzine; Benztropine; Crying; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Nervous System; Nicotine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Salivation; Scopolamine; Seizures; Time Factors

1987
Development of amygdaloid cholinergic mediation of passive avoidance learning in the rat. I. Muscarinic mechanisms.
    Experimental brain research, 1987, Volume: 67, Issue:1

    Topics: Acetylcholine; Age Factors; Amygdala; Animals; Arecoline; Atropine; Avoidance Learning; Brain; Cholinergic Fibers; Conditioning, Classical; Female; Male; Microinjections; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Muscarinic

1987
[Plasma enzymes inactivating alkaloids].
    Biokhimiia (Moscow, Russia), 1986, Volume: 51, Issue:4

    Topics: Alkaloids; Animals; Arecoline; Atropine; Blood Proteins; Chromatography, DEAE-Cellulose; Cyclic N-Oxides; Electrophoresis, Polyacrylamide Gel; Enzymes; In Vitro Techniques; Molecular Weight; Rats

1986
Restraint stress decreases afternoon plasma prolactin levels in female rats. Influence of neural antagonists and agonists on restraint-induced changes in plasma prolactin and corticosterone.
    Neuroendocrinology, 1986, Volume: 43, Issue:2

    Topics: Animals; Arecoline; Atropine; Bicuculline; Corticosterone; Female; Injections, Intravenous; Morphine; Naloxone; Ovariectomy; Parasympathomimetics; Phenoxybenzamine; Phentolamine; Pimozide; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Sympathomimetics

1986
[Products of alkaloid oxidation by a blood plasma hemeprotein].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 102, Issue:7

    Topics: Alkaloids; Animals; Arecoline; Atropine; Hemeproteins; In Vitro Techniques; Oxidation-Reduction; Rats

1986
Muscarinic acetylcholine receptors in the rabbit ciliary body smooth muscle: spare receptors and threshold phenomenon.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:1

    Topics: Animals; Arecoline; Atropine; Carbachol; Ciliary Body; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Oxotremorine; Phenoxybenzamine; Pilocarpine; Rabbits; Receptors, Muscarinic

1985
Ethanol withdrawal tremor does not interact with physostigmine-induced tremor in rat.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:3

    Topics: Animals; Arecoline; Atropine; Ethanol; Male; Physostigmine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors; Tremor

1985
Interaction between the effects of centrally administered arecoline and leucocyte pyrogen on the activity of posterior hypothalamic neurons in the rabbit.
    Experientia, 1985, Nov-15, Volume: 41, Issue:11

    Topics: Animals; Arecoline; Atropine; Drug Interactions; Electrophysiology; Hypothalamus; Hypothalamus, Posterior; Injections, Intraventricular; Interleukin-1; Neurons; Proteins; Rabbits

1985
Effects of cholinergic drugs on aversive operant behavior induced by dorsal central gray stimulation in rats.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:3

    Topics: Animals; Arecoline; Atropine; Conditioning, Operant; Discrimination Learning; Electric Stimulation; Male; Parasympathomimetics; Periaqueductal Gray; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine

1985
The origin of the hypertensive effect of arecoline in rats.
    Pharmacology, 1973, Volume: 9, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Arecoline; Arteries; Atropine; Blood Pressure; Chemoreceptor Cells; Cocaine; Drug Synergism; Female; Ganglionic Blockers; Hexamethonium Compounds; Hypertension; Hypotension; Injections, Intra-Arterial; Injections, Intravenous; Male; Nicotine; Parasympatholytics; Rats; Reserpine; Vagotomy; Vagus Nerve

1973
Drug-induced changes of striatal cholinergic and dopaminergic functions in rats with spreading depression.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:6

    Topics: Acetylcholine; Animals; Apomorphine; Arecoline; Atropine; Basal Ganglia; Benserazide; Corpus Striatum; Cortical Spreading Depression; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Male; Nicotine; Oxotremorine; Parasympathetic Nervous System; Pargyline; Potassium Chloride; Quinolizines; Rats; Receptors, Drug; Time Factors

1973
The pressor effect of oxotremorine and arecoline in rats.
    Acta physiologica Academiae Scientiarum Hungaricae, 1973, Volume: 43, Issue:1

    Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Animals; Arecoline; Atropine; Blood Pressure; Cerebral Ventricles; Cordotomy; Female; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Morphine; Oxotremorine; Phenoxybenzamine; Phentolamine; Rats; Reserpine; Vagotomy

1973
Muscarinic cholinergic binding in rat brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:5

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Binding Sites; Binding, Competitive; Brain; Brompheniramine; Carbachol; Chlorpheniramine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methacholine Compounds; Microsomes; Mitochondria; Oxotremorine; Pilocarpine; Quaternary Ammonium Compounds; Quinuclidines; Rats; Receptors, Cholinergic; Scopolamine; Temperature; Time Factors; Tritium

1974
Melanophore aggregation in the plaice (Pleuronectes platessa L) II. In vitro effects of adrenergic drugs.
    Comparative biochemistry and physiology. A, Comparative physiology, 1974, Aug-01, Volume: 48, Issue:4

    Topics: Acetylcholine; Adaptation, Physiological; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arecoline; Atropine; Calcium; Carbachol; Catecholamines; Chromatophores; Dopamine; Epinephrine; Fishes; Guanethidine; Histamine; Isoproterenol; Melanins; Norepinephrine; Phentolamine; Pilocarpine; Potassium; Reserpine; Skin; Tyramine

1974
Influence of pharmacological agents on the growth of processes of spinal ganglion nerve cells in culture.
    The Soviet journal of developmental biology, 1974, Volume: 4, Issue:6

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Benactyzine; Chick Embryo; Choline; Decamethonium Compounds; Epinephrine; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Hexamethonium Compounds; In Vitro Techniques; Magnesium; Nerve Growth Factors; Nicotine; Norepinephrine; Parasympatholytics; Parasympathomimetics; Phentolamine; Potassium; Procaine; Propranolol; Serotonin; Sodium; Succinylcholine; Sympatholytics; Sympathomimetics; Tubocurarine

1974
Effects of some sympathomimetic drugs and their antagonists on afterdischarges elicited in chronically isolated slabs of cerebral cortex.
    British journal of pharmacology, 1971, Volume: 43, Issue:4

    Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Arecoline; Atropine; Cats; Cerebral Cortex; Electric Stimulation; Electrophysiology; Ephedrine; Female; Male; Methamphetamine; Phenoxybenzamine; Phentolamine; Sympatholytics; Sympathomimetics; Time Factors; Tolazoline; Tyramine

1971
Comparison of the vasodilator activity of acetylcholine, cholinomimetics and other vasodilators in two vascular beds of the cat.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Abdomen; Acetylcholine; Animals; Arecoline; Atropine; Blood Pressure; Cats; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Hindlimb; Histamine; Injections, Intra-Arterial; Isoproterenol; Male; Neostigmine; Oxotremorine; Papaverine; Parasympathomimetics; Perfusion; Pilocarpine; Regional Blood Flow; Vascular Resistance; Vasodilator Agents

1974
Effect of oxotremorine on homovanillic acid concentration in the striatum of the rat.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Animals; Arecoline; Atropine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Fluorometry; Hemicholinium 3; Homovanillic Acid; Male; Mecamylamine; Nicotine; Oxotremorine; Parasympathomimetics; Phenylacetates; Physostigmine; Rats; Time Factors

1974
Studies on some possible mechanisms of potentiation of hexobarbital hypnosis by pilocarpine, muscarine and arecoline.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Alkaloids; Animals; Arecoline; Atropine; Blood Glucose; Brain Chemistry; Drug Synergism; Furans; Hexobarbital; Hypnotics and Sedatives; Liver; Male; Mice; Parasympathomimetics; Pilocarpine; Quaternary Ammonium Compounds; Sleep; Time Factors

1974
The pharmacology fo gross behavioural effects of cholinomimetic substances injected into the cerebral ventricles of unanaesthetized cats: evidence for central muscarinic mediation.
    Neuropharmacology, 1974, Volume: 13, Issue:12

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Autonomic Nervous System; Behavior, Animal; Carbachol; Cats; Cerebral Ventricles; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Emotions; Female; Gallamine Triethiodide; Hexamethonium Compounds; Injections; Male; Methacholine Compounds; Motor Activity; Nicotine; Parasympathetic Nervous System; Parasympathomimetics; Pilocarpine; Quaternary Ammonium Compounds; Scopolamine; Tubocurarine

1974
[Inhibition of nociceptive reactions in the frog using central cholinomimetics].
    Acta biologica et medica Germanica, 1972, Volume: 28, Issue:4

    Topics: Animals; Anura; Arecoline; Atropine; Decerebrate State; Female; Lethal Dose 50; Male; Methods; Nicotine; Oxotremorine; Parasympathomimetics; Rana esculenta; Reflex; Spinal Cord; Strychnine

1972
Catalepsy and circling behaviour after intracerebral injections of neuroleptic, cholinergic and anticholinergic agents into the caudate-putamen, globus pallidus and substantia nigra of rat brain.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Animals; Arecoline; Atropine; Behavior, Animal; Catalepsy; Caudate Nucleus; Corpus Striatum; Diffusion; Dose-Response Relationship, Drug; Ethyl Ethers; Extrapyramidal Tracts; Globus Pallidus; Haloperidol; Humans; Injections; Male; Motor Activity; Parasympatholytics; Parasympathomimetics; Rats; Stereotaxic Techniques; Substantia Nigra; Time Factors; Tranquilizing Agents; Tremor; Tritium

1972
Stimulation of lachrymation and salivation in the adult fowl (Gallus domesticus).
    Research in veterinary science, 1972, Volume: 13, Issue:5

    Topics: Animals; Arecoline; Atropine; Carbachol; Chickens; Female; Injections, Intramuscular; Irritants; Lacrimal Apparatus; Neostigmine; Parasympathomimetics; Physostigmine; Pilocarpine; Saliva; Secretory Rate; Spasm; Stimulation, Chemical; Tears

1972
[Antinocifensive effect of nicotine including methodical description of an automatic focal ray device].
    Acta biologica et medica Germanica, 1972, Volume: 29, Issue:3

    Topics: Animals; Arecoline; Atropine; Aza Compounds; Bridged-Ring Compounds; Dimethylamines; Dimethylphenylpiperazinium Iodide; Ganglionic Stimulants; Hemicholinium 3; Nicotine; Physical Stimulation; Rats; Reflex; Strychnine; Tail; Tetraethylammonium Compounds; Tubocurarine

1972
Atropine antagonism of arecoline-cued behavior in the rat.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jun-01, Volume: 11, Issue:11

    Topics: Animals; Arecoline; Atropine; Behavior, Animal; Conditioning, Operant; Discrimination Learning; Drug Interactions; Female; Rats; Reinforcement, Psychology

1972
Differences in the effect of drugs on young and old hearts of the house cricket, Acheta domesticus (L.).
    Comparative and general pharmacology, 1972, Volume: 3, Issue:11

    Topics: Acetylcholine; Age Factors; Aging; Animals; Arecoline; Atropine; Heart; Heart Rate; In Vitro Techniques; Insecta; Nicotine; Norepinephrine; Physostigmine; Serotonin; Tubocurarine

1972
Characteristic of cholinoreception in somatic muscle of the lamprey, Lampetra fluviatilis.
    Comparative and general pharmacology, 1972, Volume: 3, Issue:12

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Fishes; In Vitro Techniques; Methacholine Compounds; Muscles; Nicotine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phthalic Acids; Quaternary Ammonium Compounds; Receptors, Cholinergic; Receptors, Drug; Succinylcholine; Tubocurarine

1972
Effect of oxotremorine and arecoline on the inferior eyelid of the rat.
    Acta physiologica Academiae Scientiarum Hungaricae, 1972, Volume: 42, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Arecoline; Atropine; Eyelids; Female; Guanethidine; Hypertension; Male; Muscle Contraction; Oxotremorine; Phentolamine; Rats

1972
Biting attack in cats: evidence for central muscarinic mediation.
    Brain research, 1973, Mar-15, Volume: 51

    Topics: Aggression; Animals; Arecoline; Atropine; Behavior, Animal; Cats; Female; Humans; Injections, Intraperitoneal; Male; Oxotremorine; Parasympathomimetics

1973
Effects of cholinergic drugs on prey-killing by rodents.
    Physiology & behavior, 1973, Volume: 10, Issue:6

    Topics: Aggression; Animals; Appetitive Behavior; Arecoline; Atropine; Dose-Response Relationship, Drug; Humans; Male; Methacholine Compounds; Neostigmine; Nicotine; Oxotremorine; Parasympathomimetics; Physostigmine; Pilocarpine; Rats; Receptors, Cholinergic; Scopolamine

1973
[Structure-activity relationships of isoarecaidine esters].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:10

    Topics: Animals; Arecoline; Atropine; Blood Pressure; Carbachol; Depression, Chemical; Dose-Response Relationship, Drug; Esters; Female; Guinea Pigs; Heart Atria; Heart Rate; Hydrogenation; Ileum; In Vitro Techniques; Isomerism; Male; Muscle Contraction; Rats; Structure-Activity Relationship; Sympathomimetics

1973
Identification of the nicotinic and muscarinic acetylcholine receptors in subcellular fractions of mouse brain.
    Neuropharmacology, 1974, Volume: 13, Issue:1

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Brain; Bungarotoxins; Centrifugation, Density Gradient; Decamethonium Compounds; Dialysis; Gallamine Triethiodide; In Vitro Techniques; Iodine Radioisotopes; Membranes; Mice; Mitochondria; Nicotine; Pyridostigmine Bromide; Receptors, Adrenergic; Receptors, Cholinergic; Scopolamine; Subcellular Fractions; Sucrose; Synaptosomes; Tritium

1974
Cholinergic modification of naloxone-induced jumping in morphine dependent mice.
    European journal of pharmacology, 1974, Volume: 26, Issue:1

    Topics: Animals; Arecoline; Atropine; Behavior, Animal; Benztropine; Brain Chemistry; Dimethylphenylpiperazinium Iodide; Humans; Lobeline; Male; Mecamylamine; Mice; Mice, Inbred ICR; Morphine Dependence; Naloxone; Nicotine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pempidine; Physostigmine; Pilocarpine; Tremorine; Tritium

1974
Unilateral diuresis by infusing arecoline into renal portal system of hens.
    The American journal of physiology, 1967, Volume: 212, Issue:6

    Topics: Animals; Arecoline; Atropine; Chickens; Chlorides; Diuresis; Female; Kidney Tubules; Sodium; Urine

1967
[The cholinergic component in the central regulation of arterial pressure in cats].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1972, Volume: 58, Issue:6

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Benactyzine; Blood Pressure; Cats; Nicotinic Acids; Parasympatholytics; Tremorine; Vasomotor System

1972
Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:6

    Topics: 4-Aminopyridine; Aminopyridines; Animals; Arecoline; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Drug Interactions; Hexamethonium; Hexamethonium Compounds; Hypoxia; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Parasympathomimetics; Physostigmine; Structure-Activity Relationship

1983
[Effect of central effective substances on alcohol preference].
    Biomedica biochimica acta, 1983, Volume: 42, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Animals; Arecoline; Atropine; Central Nervous System Stimulants; Cyproheptadine; Disease Models, Animal; Drinking Behavior; Food Preferences; Haloperidol; Humans; Isoproterenol; Male; Methamphetamine; Mice; Phenoxybenzamine; Picrotoxin; Propranolol

1983
Pharmacological evidence for cardiac muscarinic receptor subtypes.
    Life sciences, 1984, Oct-22, Volume: 35, Issue:17

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzodiazepinones; Binding Sites; Butylscopolammonium Bromide; Carbachol; Female; Guinea Pigs; Heart Rate; Male; Myocardial Contraction; Myocardium; N-Methylscopolamine; Pirenzepine; Quaternary Ammonium Compounds; Receptors, Muscarinic; Scopolamine Derivatives

1984
[The role of the cholinergic system in controlling the nocturnal prolactin surge in pseudopregnant rats].
    Nihon Naibunpi Gakkai zasshi, 1983, Jun-20, Volume: 59, Issue:6

    Topics: Animals; Arecoline; Atropine; Female; Parasympathetic Nervous System; Pilocarpine; Pimozide; Prolactin; Pseudopregnancy; Rats; Rats, Inbred Strains

1983
Effect of zinc on [3H]-QNB displacement by cholinergic agonists and antagonists.
    Biochemical pharmacology, 1983, Jan-15, Volume: 32, Issue:2

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Binding, Competitive; Male; Oxotremorine; Parasympatholytics; Parasympathomimetics; Physostigmine; Pilocarpine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Zinc

1983
Scopolamine self-administration: cholinergic involvement in reward mechanisms.
    Life sciences, 1982, Aug-30, Volume: 31, Issue:9

    Topics: Animals; Arecoline; Atropine; Behavior, Animal; Female; Mecamylamine; N-Methylscopolamine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Scopolamine; Scopolamine Derivatives; Self Administration

1982
Muscarinic acetylcholine receptors on an identified motor neurone in the cockroach, Periplaneta americana.
    Neuroscience letters, 1994, Jul-04, Volume: 175, Issue:1-2

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Atropine; Dose-Response Relationship, Drug; Evoked Potentials; Ganglia, Invertebrate; In Vitro Techniques; Male; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Periplaneta; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Vertebrates

1994
Functional characterization of a muscarinic receptor stimulating gastrin release from rabbit antral G-cells in primary culture.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Animals; Arecoline; Atropine; Benzodiazepinones; Carbachol; Cell Adhesion; Cell Separation; Cells, Cultured; Gastrins; Immunohistochemistry; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Rabbits; Receptors, Muscarinic

1994
New classes of antimuscarinic agents endowed with selective antispasmodic properties. 1-Arylsulfonyl pyrrolidin-2-ones and 2-thiones, 1-arylsulfonyl piperidin-2-ones and 2-thiones and 1-arylsulfonyl hexahydro-2H-azepin-2-one.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:4

    Topics: Animals; Arecoline; Atropine; Azepines; Butylscopolammonium Bromide; Carbachol; Gastric Acid; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pupil; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Sulfones

1994
Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines.
    Journal of molecular neuroscience : MN, 1996,Spring, Volume: 7, Issue:1

    Topics: Amyloid beta-Protein Precursor; Animals; Arecoline; Astrocytes; Atropine; Calcimycin; Carbachol; Cholinesterase Inhibitors; Enzyme Inhibitors; HeLa Cells; Humans; Ionophores; Muscarinic Agonists; Muscarinic Antagonists; Neuroblastoma; PC12 Cells; Physostigmine; Rats; Staurosporine; Tacrine

1996
Pontine reticular formation is involved in catalepsy produced by cholinergic drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:2

    Topics: Animals; Arecoline; Atropine; Carbachol; Catalepsy; Cholinergic Agents; Drug Interactions; Injections, Intraperitoneal; Kainic Acid; Male; Microinjections; Physostigmine; Rats; Reticular Formation; Stereotaxic Techniques; Thalamic Nuclei

1997
Arecoline cytotoxicity on human oral mucosal fibroblasts related to cellular thiol and esterase activities.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:7

    Topics: Acetylcysteine; Antimetabolites; Areca; Arecoline; Atropine; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Esterases; Expectorants; Fibroblasts; Ganglionic Stimulants; Humans; Maleates; Mouth Mucosa; Muscarinic Antagonists; Plants, Medicinal; Sulfhydryl Compounds; Thiolester Hydrolases

1999
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-04, Volume: 97, Issue:1

    Topics: Ancylostoma; Ancylostomatoidea; Animals; Arecoline; Atropine; Caenorhabditis elegans; Insulin; Larva; Muscarinic Agonists; Muscarinic Antagonists; Neuropeptides; Neurotransmitter Agents; Oxotremorine; Pilocarpine; Signal Transduction

2000
Arecoline excites rat locus coeruleus neurons by activating the M2-muscarinic receptor.
    The Chinese journal of physiology, 2000, Mar-31, Volume: 43, Issue:1

    Topics: Alzheimer Disease; Animals; Arecoline; Atropine; Cholinergic Agonists; Diamines; Hexamethonium; Locus Coeruleus; Male; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic

2000
Carbachol and acetylcholine delay the early postdenervation depolarization of muscle fibres through M1-cholinergic receptors.
    Neuroscience research, 2000, Volume: 37, Issue:4

    Topics: Acetylcholine; Animals; Arecoline; Atropine; Carbachol; Culture Techniques; Diaphragm; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Muscle Denervation; Muscle Fibers, Skeletal; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic

2000
A pertussis toxin-sensitive 8-lipoxygenase pathway is activated by a nicotinic acetylcholine receptor in aplysia neurons.
    Journal of neurophysiology, 2001, Volume: 85, Issue:5

    Topics: Acetylcholine; Animals; Aplysia; Arachidonate Lipoxygenases; Arachidonic Acids; Arecoline; Atropine; Bungarotoxins; Chloride Channels; Chlorides; Choline; Cholinergic Antagonists; Conotoxins; Depression, Chemical; Enzyme Activation; Ganglia, Invertebrate; Hexamethonium; Hydroxyeicosatetraenoic Acids; Ion Channel Gating; Ion Transport; Nerve Tissue Proteins; Neurons; Nicotine; Nicotinic Agonists; Pertussis Toxin; Receptor Cross-Talk; Receptors, Nicotinic; Tetraethylammonium; Tubocurarine; Virulence Factors, Bordetella

2001
Mechanism of vascular relaxation by cholinomimetic drugs with special reference to pilocarpine and arecoline.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:1

    Topics: Animals; Arecoline; Atropine; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; In Vitro Techniques; Latanoprost; Phenylephrine; Physostigmine; Pilocarpine; Prostaglandins F, Synthetic; Rats; Vasodilation; Vasodilator Agents

2002
Autonomous activity in the isolated guinea pig bladder.
    Experimental physiology, 2003, Volume: 88, Issue:1

    Topics: Animals; Arecoline; Atropine; Female; Guinea Pigs; Homeostasis; In Vitro Techniques; Movement; Muscle Contraction; Muscle, Smooth; Pressure; Tetrodotoxin; Urinary Bladder; Urination

2003
Agonist- and nerve-induced phasic activity in the isolated whole bladder of the guinea pig: evidence for two types of bladder activity.
    Experimental physiology, 2003, Volume: 88, Issue:3

    Topics: Anesthetics, Local; Animals; Arecoline; Atropine; Carbachol; Cholinergic Agonists; Electric Stimulation; Female; Guinea Pigs; Hexamethonium; Lobeline; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Nicotinic Agonists; Nicotinic Antagonists; Stimulation, Chemical; Tetrodotoxin; Urinary Bladder

2003
ARECOLINE PHENOMENON IN THE ANALYSIS OF THE ACTION OF DRUGS ON CENTRAL NERVOUS SYSTEM.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Amphetamine; Amphetamines; Animals; Arecoline; Atropine; Benactyzine; Birds; Chlorpromazine; Eyelids; Guinea Pigs; Parasympathetic Nervous System; Parasympatholytics; Parasympathomimetics; Pharmacology; Phenylacetates; Rabbits; Rats; Reflex; Research; Scopolamine; Species Specificity; Sympathetic Nervous System; Toxicology

1964
Cholinergic modulation of nociceptive responses in vivo and neuropeptide release in vitro at the level of the primary sensory neuron.
    Pain, 2004, Volume: 107, Issue:1-2

    Topics: Acetylcholine; Analysis of Variance; Animals; Arecoline; Atropine; Behavior, Animal; Bungarotoxins; Calcitonin Gene-Related Peptide; Capsaicin; Cell Count; Disinfectants; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Formaldehyde; Gallamine Triethiodide; Gene Expression Regulation; Grooming; In Situ Hybridization; In Vitro Techniques; Male; Mecamylamine; Mouth Mucosa; Muscarinic Antagonists; Neurons, Afferent; Nicotinic Antagonists; Pain; Pain Measurement; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Drug; RNA, Messenger; Time; Trigeminal Ganglion

2004
Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill.
    BMC neuroscience, 2004, Jul-13, Volume: 5

    Topics: Adenylyl Cyclase Inhibitors; Animals; Arecoline; Atropine; Carbachol; Colforsin; Cyclic AMP; Cytoplasmic Granules; Light; Muscarinic Agonists; Muscarinic Antagonists; Perciformes; Pigment Epithelium of Eye; Piperidines; Pirenzepine; Quaternary Ammonium Compounds; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Retinal Pigments; Second Messenger Systems; Tropicamide

2004
Arecoline excites the colonic smooth muscle motility via M3 receptor in rabbits.
    The Chinese journal of physiology, 2004, Jun-30, Volume: 47, Issue:2

    Topics: Animals; Arecoline; Atropine; Colon; Dose-Response Relationship, Drug; Female; Ganglionic Stimulants; Gastrointestinal Motility; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Piperidines; Rabbits; Receptor, Muscarinic M2; Receptor, Muscarinic M3

2004
Ultrastructural and hormonal modulations of the thyroid gland following arecoline treatment in albino mice.
    Molecular and cellular endocrinology, 2010, May-05, Volume: 319, Issue:1-2

    Topics: Analysis of Variance; Animals; Arecoline; Atropine; Cell Size; Cholinergic Agonists; Cholinergic Antagonists; Epithelial Cells; Male; Mice; Microscopy, Electron, Transmission; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2010
Effect of cholinergic drugs on the activity of basic carboxypeptidases in rat nervous tissue.
    Biochemistry. Biokhimiia, 2011, Volume: 76, Issue:10

    Topics: Adrenal Glands; Animals; Arecoline; Atropine; Brain; Carboxypeptidase H; Cholinergic Agents; Enzyme Inhibitors; Male; Mecamylamine; Neuropeptides; Nicotine; Phenylmethylsulfonyl Fluoride; Rats

2011
FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Animals; Arecoline; Atropine; Binding, Competitive; Cell Membrane; Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Kinetics; Luminescent Proteins; Male; Methacholine Chloride; Mice; Microscopy, Confocal; Muscarinic Agonists; Piperidines; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Transfection

2012
Stimulation of non-neuronal muscarinic receptors enhances chemerin/ChemR23 system in dysfunctional endothelial cells.
    Life sciences, 2013, Jan-17, Volume: 92, Issue:1

    Topics: Adipokines; Animals; Aorta, Thoracic; Arecoline; Atropine; Blotting, Western; Chemokines; Endothelial Cells; Gene Expression Regulation; Homocysteine; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2013
Arecoline hydrobromide enhances jejunum smooth muscle contractility via voltage-dependent potassium channels in W/Wv mice.
    Physiological research, 2021, 07-12, Volume: 70, Issue:3

    Topics: Animals; Arecoline; Atropine; Dose-Response Relationship, Drug; Gastrointestinal Motility; Jejunum; Mice; Muscle Contraction; Muscle, Smooth; Nicardipine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2021