atropine has been researched along with alprostadil in 37 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (alprostadil) | Trials (alprostadil) | Recent Studies (post-2010) (alprostadil) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 7,136 | 864 | 761 |
| Protein | Taxonomy | atropine (IC50) | alprostadil (IC50) |
|---|---|---|---|
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 2.3 | |
| Solute carrier organic anion transporter family member 2B1 | Rattus norvegicus (Norway rat) | 0.0358 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (35.14) | 18.7374 |
| 1990's | 15 (40.54) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 5 (13.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Akerman, KE; Heikkilä, J; Jansson, C | 1 |
| Nakagawa-Yagi, Y; Saito, Y; Takada, Y; Takayama, M | 1 |
| Hollenberg, MD; Lederis, K; Yamaguchi, K | 1 |
| Fields, JZ; Haydek, JM; Keshavarzian, A; Stinneford, JG; Zepeda, DO | 1 |
| Berglindh, T; Nylander, O; Obrink, KJ | 1 |
| Askelöf, P; Bartfai, T; Gillenius, P; Westlind-Danielsson, A | 1 |
| Ikegami, K; Mutoh, S; Sakanashi, M; Ueda, S; Yano, S; Yoshida, M | 1 |
| Alino, SF; Garcia, D; Uvnäs-Moberg, K | 1 |
| Brunsson, I; Jodal, M; Lundgren, O; Sjöqvist, A | 1 |
| Koenig, RJ; Smith, RJ | 1 |
| Dharmsathaphorn, K; Pandol, SJ | 1 |
| Hoffman, BB; Thomas, JM | 1 |
| Basu, S; Jónasson, H | 1 |
| Duncan, R; Krzanowski, J; Lockey, R; Martin, DF; Perez-Cruet, M; Polson, J; Shimoda, T | 1 |
| Clark, RB; Green, DA | 2 |
| Abe, H; Chihara, K; Kaji, H; Okimura, Y; Tai, S | 1 |
| Barbieri, L; Bergamaschi, F; Ferini-Strambi, L; Guazzoni, G; Montorsi, F; Rigatti, P | 1 |
| Barbieri, L; Bergamaschi, F; Da Pozzo, L; Guazzoni, G; Montorsi, F; Orlandini, A; Rigatti, P | 1 |
| Bergamaschi, F; Dodesini, A; Guazzoni, G; Miani, A; Montorsi, F; Pizzini, G; Rigatti, P | 1 |
| Kubota, M; Nakabou, Y; Ojima, M; Takada, K | 1 |
| Del Noce, G; Fontana, D; Rolle, L; Rosso, C; Tamagnone, A | 1 |
| Bergamaschi, F; Guazzoni, G; Miani, A; Montorsi, F; Pizzini, G; Pozza, G; Rigatti, P; Zucconi, M | 1 |
| Hollenberg, MD; Muramatsu, I | 1 |
| Goldstein, I; Moreland, RB; Palmer, MS; Traish, AM | 1 |
| Sogari, PR; Souto, CA; Telöken, C | 1 |
| Baniel, J; Israilov, S; Livne, P; Segenreich, E; Shmueli, J | 1 |
| Kakiailatu, FA | 1 |
| Baniel, J; Engelstein, D; Israilov, S; Livne, PM; Niv, E; Segenreich, E; Shmueli, J | 1 |
| Kharlamb, AB; Krauss, AH; Nieves, AL; Nilsson, SF; Toris, CB; Woodward, DF | 1 |
| Goldstein, I | 1 |
1 trial(s) available for atropine and alprostadil
| Article | Year |
|---|---|
Atropine role in the pharmacological erection test: study of 228 patients.
Topics: Adult; Aged; Alprostadil; Atropine; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Phentolamine; Risk Factors; Vasodilator Agents | 1997 |
36 other study(ies) available for atropine and alprostadil
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Differential coupling of muscarinic receptors to Ca2+ mobilization and cyclic AMP in SH-SY5Y and IMR 32 neuroblastoma cells.
Topics: Acetylcholine; Alprostadil; Atropine; Calcium; Carbachol; Cyclic AMP; Humans; Methacholine Chloride; Muscarine; Neuroblastoma; Pertussis Toxin; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Carbachol enhances forskolin-stimulated cyclic AMP accumulation via activation of calmodulin system in human neuroblastoma SH-SY5Y cells.
Topics: Adenosine; Alprostadil; Atropine; Calmodulin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Drug Synergism; Humans; Kinetics; Naphthalenes; Neuroblastoma; Pertussis Toxin; Polycyclic Compounds; Protein Kinase C; Trifluoperazine; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1991 |
Contraction of porcine ocular ciliary muscle by epidermal growth factor-urogastrone.
Topics: Alprostadil; Animals; Atropine; Calcium; Ciliary Body; Epidermal Growth Factor; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Phentolamine; Prostaglandins; Recombinant Proteins; Swine; Tetrodotoxin; Vasopressins | 1990 |
Gastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alprostadil; Animals; Atropine; Duodenal Ulcer; Female; Gastric Acid; Injections, Subcutaneous; Misoprostol; Omeprazole; Prostaglandins; Rats; Rats, Inbred F344; Stomach Ulcer; Time Factors | 1990 |
Prostaglandin interaction with histamine release and parietal cell activity in isolated gastric glands.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Alprostadil; Aminopyrine; Animals; Atropine; Dinoprostone; Drug Interactions; Gastric Mucosa; Histamine Release; Male; Oxygen Consumption; Parietal Cells, Gastric; Pentagastrin; Prostaglandins; Prostaglandins E; Rabbits; Somatostatin | 1986 |
Chronic exposure to pertussis toxin alters muscarinic receptor-mediated regulation of cyclic AMP metabolism in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Atropine; Carbachol; Cyclic AMP; Glioma; Hybrid Cells; Neuroblastoma; Pertussis Toxin; Receptors, Muscarinic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Comparison of the effects of primary prostaglandins on isolated human urinary bladder.
Topics: Acetylcholine; Aged; Alprostadil; Atropine; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Phentolamine; Prostaglandins; Prostaglandins E; Prostaglandins F; Urinary Bladder | 1985 |
Effect of intragastric pH, prostaglandins and prostaglandin synthesis inhibitors on the release of gastrin and somatostatin into the gastric lumen of anaesthetized rats.
Topics: Alprostadil; Animals; Aspirin; Atropine; Dinoprostone; Electric Stimulation; Gastric Mucosa; Gastrins; Hydrogen-Ion Concentration; Indomethacin; Male; Prostaglandins; Prostaglandins A; Prostaglandins E; Pyloric Antrum; Rats; Rats, Inbred Strains; Somatostatin; Vagus Nerve | 1986 |
Mechanisms underlying the small intestinal fluid secretion caused by arachidonic acid, prostaglandin E1 and prostaglandin E2 in the rat in vivo.
Topics: Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Body Water; Cyclic AMP; Denervation; Dinoprostone; Hexamethonium; Hexamethonium Compounds; Injections, Intra-Arterial; Intestinal Absorption; Intestinal Secretions; Jejunum; Male; Rats; Rats, Inbred Strains | 1987 |
L6 cells as a tissue culture model for thyroid hormone effects on skeletal muscle metabolism.
Topics: Adult; Alprostadil; Atropine; Carbachol; Cyclic AMP; Female; Fibroblasts; Humans; Kinetics; Pregnancy; Prostaglandins E; Quinuclidinyl Benzilate; Receptors, Muscarinic; Skin | 1985 |
Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line.
Topics: Alprostadil; Atropine; Barium; Bumetanide; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane; Chlorides; Colon; Cyclic AMP; Drug Synergism; Electric Conductivity; Epithelium; Humans; Kinetics; Potassium; Vasoactive Intestinal Peptide | 1986 |
Muscarinic cholinergic receptor-induced enhancement of PGE1-stimulated cAMP accumulation in neuroblastoma X glioma cells: prevention by pertussis toxin.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Atropine; Carbachol; Cell Line; Cyclic AMP; Enzyme Activation; Glioma; GTP-Binding Proteins; Neuroblastoma; Pertussis Toxin; Receptors, Muscarinic; Receptors, Prostaglandin; Virulence Factors, Bordetella | 1986 |
Atropine-antagonized miosis induced in the goat by intravenous infusions of prostaglandin E (PGE1 and PGE2).
Topics: Alprostadil; Animals; Arginine Vasopressin; Atropine; Body Temperature; Dinoprost; Dinoprostone; Diuresis; Female; Goats; Infusions, Parenteral; Kidney; Meiosis; Prostaglandins E; Prostaglandins F; Pupil; Water | 1986 |
Lower airway smooth muscle contraction induced by Ptychodiscus brevis (red tide) toxin.
Topics: Acetylcholine; Alprostadil; Animals; Atropine; Dogs; Marine Toxins; Muscle Contraction; Muscle, Smooth; Neostigmine; Tetrodotoxin; Verapamil | 1987 |
Comparison of the muscarinic-cholinergic and lysophosphatidate inhibition of fibroblast adenylate cyclase demonstrating desensitization to the cholinergic stimulus.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Atropine; Carbachol; Cyclic AMP; Epinephrine; Fibroblasts; Half-Life; Humans; Lysophospholipids; Phosphatidic Acids; Prostaglandins E; Receptors, Cholinergic; Receptors, Muscarinic | 1981 |
Specific muscarinic-cholinergic desensitization in the neuroblastoma-glioma hybrid NG108-15.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Atropine; Carbachol; Cell Line; Glioma; Hybrid Cells; Mice; Neuroblastoma; Prostaglandins E; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1982 |
Neurokinin receptor antagonists inhibit the binding of growth hormone-releasing peptide to EP-1 human neuroblastoma cells.
Topics: Alprostadil; Animals; Atropine; Carbachol; Cell Line; Growth Hormone-Releasing Hormone; Guanylyl Imidodiphosphate; HeLa Cells; Humans; Hypothalamus; Kinetics; Neuroblastoma; Neuropeptides; Oligopeptides; Pituitary Gland; Rats; Receptors, Tachykinin; Structure-Activity Relationship; Tumor Cells, Cultured | 1995 |
Four-drug intracavernous therapy for impotence due to corporeal veno-occlusive dysfunction.
Topics: Alprostadil; Atropine; Drug Administration Schedule; Drug Combinations; Erectile Dysfunction; Follow-Up Studies; Humans; Injections; Male; Middle Aged; Papaverine; Penile Erection; Penis; Peripheral Vascular Diseases; Phentolamine; Self Administration; Solutions | 1993 |
Intracavernous vasoactive pharmacotherapy: the impact of a new self-injection device.
Topics: Alprostadil; Atropine; Drug Combinations; Equipment Design; Erectile Dysfunction; Humans; Injections; Male; Papaverine; Penile Erection; Phentolamine; Self Administration; Syringes | 1993 |
Effectiveness and safety of multidrug intracavernous therapy for vasculogenic impotence.
Topics: Alprostadil; Atropine; Drug Synergism; Drug Therapy, Combination; Erectile Dysfunction; Humans; Injections, Intravenous; Male; Papaverine; Penis; Phentolamine | 1993 |
A possible approach to the suppression of side effects induced by PGE1.
Topics: Alprostadil; Animals; Atropine; Capillary Permeability; Gabexate; Guanidines; Guinea Pigs; Histamine; Ileum; Inflammation; Male; Muscle Contraction; Papaverine; Piperidines; Rats | 1995 |
[The pharmaco-erection test].
Topics: Alprostadil; Atropine; Diagnosis, Differential; Drug Combinations; Erectile Dysfunction; Humans; Impotence, Vasculogenic; Male; Papaverine; Penile Diseases; Penile Erection; Phentolamine; Vasodilator Agents | 1994 |
Clinical reliability of multi-drug intracavernous vasoactive pharmacotherapy for diabetic impotence.
Topics: Adult; Aged; Alprostadil; Atropine; Diabetes Complications; Drug Combinations; Erectile Dysfunction; Follow-Up Studies; Humans; Injections; Male; Middle Aged; Papaverine; Penile Erection; Phentolamine; Self Administration; Treatment Outcome | 1994 |
Potentiation of sensory tachykininergic and parasympathetic cholinergic transmission by epidermal growth factor.
Topics: Acetylcholine; Alprostadil; Animals; Atropine; Capsaicin; Epidermal Growth Factor; Female; Genistein; In Vitro Techniques; Indomethacin; Iris; Isoflavones; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Rabbits; Synaptic Transmission; Tachykinins | 1993 |
Expression of functional muscarinic acetylcholine receptor subtypes in human corpus cavernosum and in cultured smooth muscle cells.
Topics: Adenylyl Cyclases; Alprostadil; Atropine; Carbachol; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Humans; In Situ Hybridization; Isoproterenol; Kinetics; Male; Models, Biological; Muscle, Smooth; Penis; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; RNA, Messenger; Transcription, Genetic | 1995 |
Progressive treatment of erectile dysfunction with intracorporeal injections of different combinations of vasoactive agents.
Topics: Adult; Aged; Aged, 80 and over; Alprostadil; Atropine; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penis; Phentolamine; Vasodilator Agents | 1999 |
The role of nitric oxide in the mechanism of penile erection.
Topics: Acetylcholine; Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Fibers; Alprostadil; Animals; Atropine; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; Isoenzymes; Isoproterenol; Macaca nemestrina; Male; Microcirculation; Models, Biological; Muscarinic Antagonists; Muscle, Smooth; Muscle, Smooth, Vascular; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Penile Erection; Penis; Propranolol; Second Messenger Systems; Vasodilator Agents | 2000 |
Intracavernous injections for erectile dysfunction in patients with cardiovascular diseases and failure or contraindications for sildenafil citrate.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Alprostadil; Atropine; Cardiovascular Diseases; Coitus; Contraindications; Drug Combinations; Erectile Dysfunction; Follow-Up Studies; Humans; Injections; Male; Middle Aged; Muscarinic Antagonists; Papaverine; Penis; Phentolamine; Piperazines; Purines; Retreatment; Sildenafil Citrate; Sulfones; Treatment Failure; Vasodilator Agents | 2002 |
Prostanoid EP4 receptor stimulation produces ocular hypotension by a mechanism that does not appear to involve uveoscleral outflow.
Topics: Alprostadil; Animals; Anterior Chamber; Antihypertensive Agents; Aqueous Humor; Atropine; Ciliary Body; Dextrans; Dinoprostone; Disease Models, Animal; Female; Fluorescein-5-isothiocyanate; Fluorophotometry; Humans; Intraocular Pressure; Isometric Contraction; Macaca fascicularis; Muscle, Smooth; Ocular Hypotension; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Sclera; Tonometry, Ocular; Transfection; Uvea | 2009 |
My pet peeve.
Topics: Adrenergic alpha-Antagonists; Advertising; Alprostadil; Atropine; Attitude of Health Personnel; Drug Therapy, Combination; Ejaculation; Humans; Injections, Intravenous; Male; Papaverine; Parasympatholytics; Patient Education as Topic; Penile Induration; Penis; Phentolamine; Sexual Dysfunction, Physiological; Truth Disclosure; Vasodilator Agents | 2010 |