atropine has been researched along with alprenolol in 42 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (alprenolol) | Trials (alprenolol) | Recent Studies (post-2010) (alprenolol) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 1,146 | 121 | 59 |
| Protein | Taxonomy | atropine (IC50) | alprenolol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.0031 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.007 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.63 | |
| Beta-3 adrenergic receptor | Homo sapiens (human) | 0.0023 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0049 | |
| Squalene synthase | Rattus norvegicus (Norway rat) | 4.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (50.00) | 18.7374 |
| 1990's | 8 (19.05) | 18.2507 |
| 2000's | 8 (19.05) | 29.6817 |
| 2010's | 5 (11.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Hib, J | 1 |
| Pöntinen, PJ | 2 |
| Elonen, E | 1 |
| Chiba, S | 2 |
| Chiba, S; Imai, Y | 1 |
| Firestein, S; Shepherd, GM | 1 |
| Fekete, Z; Murty, VL; Sengupta, S; Slomiany, A; Slomiany, BL | 1 |
| Piotrowski, E; Sengupta, S; Slomiany, A; Slomiany, BL | 2 |
| de Borda, LS; Gimeno, AL; Gimeno, MF | 1 |
| Hashimoto, K; Kubota, K | 1 |
| Hayman, DG; Ireson, JD; Leslie, GB; Smith, S | 1 |
| Day, MD; Roach, AG | 1 |
| Polidoro, J; Seeber, AM; Taquini, AC | 1 |
| Combre, A; Delort, P; Duchène-Marullaz, P; Lapalus, P | 1 |
| Holmberg, S; Husaini, MH; Kvasnicka, J; Ryèn, L | 1 |
| Bassett, AL; Danilo, P; Gelband, H; Nilsson, K; Wiggins, JR | 1 |
| Folkow, B; Hallbäck, M | 1 |
| Endoh, M; Hashimoto, K; Kimura, T | 1 |
| Battersby, LA; Cruickshank, JM; Prichard, BN | 1 |
| Brown, LA; Longmore, WJ | 1 |
| Cosentino, M; Costa, A; Crema, A; D'Angelo, L; De Ponti, F; Frigo, G; Gibelli, G; Girani, M | 1 |
| Fukada, Y; Haga, K; Haga, T; Kameyama, K; Katada, T; Kontani, K | 1 |
| Baranowska, B; Kawalec, M; Krawczyk, E; Płlonowski, A; Radzikowska, M; Roguski, K; Wasilewska-Dziubińska, E | 1 |
| Ogawa, N | 1 |
2 review(s) available for atropine and alprenolol
| Article | Year |
|---|---|
Overdosage with beta-adrenergic blocking agents.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Atropine; Blood Glucose; Cardiovascular System; Central Nervous System; Drug Tolerance; Heart Rate; Humans; Kinetics; Oxprenolol; Pindolol; Propranolol; Respiration; Sotalol | 1984 |
[Analysis and characterization of ligand-receptor binding systems].
Topics: Alprenolol; Animals; Atropine; Binding, Competitive; Carbachol; Dihydroalprenolol; Humans; Ligands; Metoprolol; Receptors, Cell Surface; Receptors, Neurotransmitter | 1997 |
40 other study(ies) available for atropine and alprenolol
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors | 1980 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Effects of autonomic drugs on epididymal contractions.
Topics: Acetylcholine; Alprenolol; Animals; Atropine; Epididymis; Epinephrine; Male; Metaproterenol; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Sympatholytics | 1976 |
Cardiovascular effects of local adrenaline infiltration during halothane anaesthesia and adrenergic beta-receptor blockade in man.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Alprenolol; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Child; Epinephrine; Female; Halothane; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Monitoring, Physiologic; Practolol; Propranolol | 1978 |
Cardiovascular effects of local adrenaline infiltration during neurolept analgesia and adrenergic beta-receptor blockade in man.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Arrhythmias, Cardiac; Atropine; Blood Pressure; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Neuroleptanalgesia; Propranolol | 1978 |
Effect of beta-adrenoceptor blocking drugs, physostigmine, and atropine on the toxicity of doxepin in mice.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atropine; Doxepin; Drug Interactions; Electrocardiography; Heart Rate; Male; Mice; Physostigmine; Practolol; Propanolamines; Propranolol | 1975 |
Mechanism of chronotropic and inotropic effects of phenylephrine.
Topics: Alprenolol; Animals; Atropine; Depression, Chemical; Desipramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Heart Ventricles; In Vitro Techniques; Injections, Intra-Arterial; Levobunolol; Methoxamine; Myocardial Contraction; Phentolamine; Phenylephrine; Stimulation, Chemical; Tetrodotoxin | 1977 |
Positive chronotropic and negative inotropic actions of vasopressin in isolated blood-perfused canine atrium.
Topics: Acetylcholine; Alprenolol; Animals; Atrial Function; Atropine; Blood; Dogs; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; Myocardial Contraction; Norepinephrine; Sinoatrial Node; Vasopressins | 1977 |
Pharmacologic analysis of papaverine-induced positive chronotropic and inotropic effects.
Topics: Alprenolol; Animals; Atropine; Desipramine; Heart; Heart Rate; In Vitro Techniques; Manganese; Myocardial Contraction; Norepinephrine; Papaverine; Stimulation, Chemical; Tetrodotoxin; Tyramine | 1976 |
Neurotransmitter antagonists block some odor responses in olfactory receptor neurons.
Topics: 2-Amino-5-phosphonovalerate; Alprenolol; Ambystoma; Animals; Atropine; Cyclic GMP; Electric Stimulation; Epithelium; In Vitro Techniques; Neurons; Neurotransmitter Agents; Nose; Odorants; Propranolol; Receptors, Neurotransmitter; Sensory Receptor Cells | 1992 |
Adrenergic and cholinergic regulation of phospholipid release in sublingual salivary gland in vitro.
Topics: Alprenolol; Animals; Atropine; Choline; In Vitro Techniques; Isoproterenol; Male; Parasympathetic Nervous System; Phospholipids; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Salivary Glands; Sympathetic Nervous System | 1991 |
Adrenergic and cholinergic regulation of gastric mucus phospholipid secretion.
Topics: Alprenolol; Animals; Atropine; Autonomic Agents; Cells, Cultured; Gastric Mucosa; Isoproterenol; Male; Phospholipids; Pilocarpine; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Role of adrenergic and cholinergic mediators in gastric mucus phospholipid secretion.
Topics: Alprenolol; Animals; Atropine; Autonomic Agents; Choline; Gastric Mucosa; Isoproterenol; Lysophosphatidylcholines; Male; Phospholipids; Pilocarpine; Rats; Rats, Inbred Strains | 1991 |
Frequency-force relationship on isolated rat and guinea pig atria. Effects of cholinergic and adrenergic receptor antagonists.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Atropine; Electric Stimulation; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Parasympatholytics; Phentolamine; Rats; Stimulation, Chemical | 1974 |
Positive chronotropic effect of ouabain in the excised and blood-perfused canine SA node preparation of the dog.
Topics: Acetylcholine; Alprenolol; Animals; Atropine; Calcium; Dogs; Electrocardiography; Electrodes; Glucagon; Heart Arrest; Heart Rate; Manganese; Norepinephrine; Ouabain; Perfusion; Propranolol; Reserpine; Sinoatrial Node; Stimulation, Chemical; Tetrodotoxin; Tyramine | 1974 |
The effects of some beta adrenergic blocking agents on the central and peripheral actions of tremorine and oxotremorine.
Topics: Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Atropine; Central Nervous System; Drug Antagonism; Ethanolamines; Hypothermia; Male; Mice; Oxotremorine; Parasympathomimetics; Propranolol; Sympatholytics; Tremor; Tremorine | 1972 |
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors | 1974 |
Cardiac pressoreceptors in rat.
Topics: Alprenolol; Animals; Aorta; Atropine; Heart; Heart Rate; Heart Ventricles; Medulla Oblongata; Neural Pathways; Pressoreceptors; Rats; Vagotomy; Vagus Nerve | 1972 |
[Nycthemeral variation in the cardiac frequency of dogs with chronic auriculo-ventricular dissociation. Role of extrinsic cardiac innervation].
Topics: Alprenolol; Animals; Atropine; Dogs; Heart Conduction System; Heart Rate; Periodicity; Pindolol; Propranolol | 1972 |
Action of verapamil on sinus node, atrioventricular, and intraventricular conduction.
Topics: Adult; Aged; Alprenolol; Arrhythmias, Cardiac; Atropine; Electrocardiography; Heart Block; Heart Conduction System; Humans; Middle Aged; Pacemaker, Artificial; Sinoatrial Node; Verapamil | 1973 |
Direct and indirect inotropic effects of nicotine on cat ventricular muscle.
Topics: Alprenolol; Animals; Atropine; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Heart Rate; Heart Ventricles; Hexamethonium Compounds; Nicotine; Papillary Muscles; Propranolol; Reserpine; Stimulation, Chemical; Time Factors; Tyramine | 1974 |
Cardiovascular responses to acute mental 'stress' in spontaneously hypertensive rats.
Topics: Alprenolol; Animals; Atropine; Blood Pressure; Depression, Chemical; Epinephrine; Female; Heart Rate; Humans; Hypertension; Light; Male; Noise; Rats; Stimulation, Chemical; Stress, Psychological; Vibration | 1974 |
Effects of perivascular nerve stimulation on the contraction and automaticity of the blood-perfused canine papillary muscle.
Topics: Alprenolol; Animals; Atropine; Cocaine; Dogs; Electric Stimulation; Female; Guanethidine; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Papillary Muscles; Perfusion; Pindolol; Propranolol; Reserpine; Tetrodotoxin | 1972 |
Adrenergic and cholinergic regulation of lung surfactant secretion in the isolated perfused rat lung and in the alveolar type II cell in culture.
Topics: Acetylcholine; Alprenolol; Animals; Atropine; Cells, Cultured; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Kinetics; Lung; Male; Perfusion; Phentolamine; Phenylephrine; Pulmonary Alveoli; Pulmonary Surfactants; Rats | 1981 |
Inhibitory effects of SR 58611A on canine colonic motility: evidence for a role of beta 3-adrenoceptors.
Topics: Adrenergic beta-Agonists; Alprenolol; Animals; Atropine; Colon; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Heart Rate; Isoproterenol; Receptors, Adrenergic, beta; Ritodrine; Tetrahydronaphthalenes | 1995 |
Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase.
Topics: Alprenolol; Animals; Atropine; Base Sequence; beta-Adrenergic Receptor Kinases; Carbachol; Cattle; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; G-Protein-Coupled Receptor Kinase 2; Genetic Vectors; GTP-Binding Proteins; Humans; Isoproterenol; Kinetics; Lung; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Protein Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Muscarinic; Recombinant Proteins; Rhodopsin; Transfection | 1993 |
Effects of PACAP and VIP on adrenal progesterone release.
Topics: Adrenal Glands; Alprenolol; Animals; Atropine; Cells, Cultured; Culture Media, Serum-Free; Female; Granulosa Cells; Hexamethonium; Hysterectomy; Naltrexone; Neuropeptides; Neurotransmitter Agents; Ovariectomy; Pituitary Adenylate Cyclase-Activating Polypeptide; Progesterone; Rats; Rats, Inbred WKY; Vasoactive Intestinal Peptide | 1996 |