Page last updated: 2024-09-05

atropine and alfentanil

atropine has been researched along with alfentanil in 20 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(alfentanil)
Trials
(alfentanil)
Recent Studies (post-2010) (alfentanil)
26,7111,2591,6971,731757172

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)alfentanil (IC50)
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0389
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.015

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's3 (15.00)18.2507
2000's5 (25.00)29.6817
2010's5 (25.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bauer, H; Böhrer, H; Jürs, G; Stubbig, K1
Dzwonczyk, RR; Hoffer, LJ; Howie, MB; Kryc, J; McDonald, JS; McSweeney, TD; Reitz, J1
Jarvis, AP; Prys-Roberts, C; Richards, MJ; Skues, MA1
Dick, W; Janik, R1
Hoffmann, P; Schockenhoff, B1
Löffler, B1
Schaps, D; Seitz, W; Striebel, H; Zuk, J1
Bragg, P; Bryson, G; Curran, M; Hull, K; Kitts, JB; Lindsay, P; Martineau, RJ; Miller, DR; Watson, JB1
Fuchs-Buder, T; Rifat, K; Sansonetti, A; Tramèr, MR1
Brearley, J; Lehnus, KS1
Brearley, JC; Gittel, C; Walters, K1

Reviews

1 review(s) available for atropine and alfentanil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

7 trial(s) available for atropine and alfentanil

ArticleYear
[Optimized analgesic sedation techniques for ESWL].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1991, Volume: 26, Issue:6

    Topics: Aged; Alfentanil; Analgesia; Atropine; Clorazepate Dipotassium; Droperidol; Female; Hemodynamics; Humans; Lithotripsy; Male; Middle Aged; Oxygen; Preanesthetic Medication

1991
A comparison of enflurane with alfentanil anaesthesia for gynaecological surgery.
    European journal of anaesthesiology, 1989, Volume: 6, Issue:4

    Topics: Adult; Alfentanil; Anesthetics; Atropine; Electroencephalography; Enflurane; Female; Fentanyl; Genitalia, Female; Hemodynamics; Humans; Middle Aged; Preanesthetic Medication

1989
Preinduction atropine or glycopyrrolate and hemodynamic changes associated with induction and maintenance of anesthesia with propofol and alfentanil.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:3

    Topics: Adult; Alfentanil; Anesthesia Recovery Period; Anesthetics; Atropine; Blood Pressure; Double-Blind Method; Female; Fentanyl; Glycopyrrolate; Heart Rate; Humans; Male; Middle Aged; Phenols; Postoperative Period; Preanesthetic Medication; Propofol; Pyrrolidines; Random Allocation

1989
[The effect of atropine, fentanyl and alfentanyl on cardiocirculatory parameters and thoracic rigidity in the induction phase of intubation anesthesia].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1988, Volume: 23, Issue:5

    Topics: Adult; Alfentanil; Anesthesia, Endotracheal; Anesthetics; Arrhythmias, Cardiac; Atropine; Blood Pressure; Fentanyl; Heart Rate; Humans; Muscle Tonus; Pectoralis Muscles; Urologic Diseases

1988
Edrophonium requirements for reversal of deep neuromuscular block following infusion of mivacurium.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:11

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Alfentanil; Ambulatory Surgical Procedures; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Atropine; Cholinesterase Inhibitors; Cholinesterases; Double-Blind Method; Edrophonium; Female; Genotype; Humans; Isoquinolines; Male; Middle Aged; Mivacurium; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Placebos; Propofol; Stereoisomerism

1995
Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:1

    Topics: Adolescent; Alfentanil; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Atropine; Child; Child, Preschool; Confidence Intervals; Elective Surgical Procedures; Hospitalization; Humans; Incidence; Injections, Intravenous; Isoflurane; Lidocaine; Mydriatics; Ondansetron; Postoperative Complications; Propofol; Reflex, Oculocardiac; Risk Factors; Strabismus; Thiopental; Vomiting

1998
Evaluation of two different radiotherapy anaesthetic protocols for dogs: a randomized clinical crossover trial.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:6

    Topics: Adjuvants, Anesthesia; Alfentanil; Anesthesia; Anesthetics, Intravenous; Animals; Atropine; Cross-Over Studies; Dog Diseases; Dogs; Female; Male; Preanesthetic Medication; Propofol; Radiotherapy

2019

Other Studies

12 other study(ies) available for atropine and alfentanil

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
[Alfentanil for neuroleptanesthesia in short operations].
    Der Anaesthesist, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Alfentanil; Atropine; Blood Pressure; Female; Fentanyl; Heart Rate; Humans; Male; Middle Aged; Neuroleptanalgesia; Pancuronium; Preanesthetic Medication; Time Factors

1985
[Alfentanil in routine clinical use. A study of 50 patients].
    Der Anaesthesist, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia, General; Atropine; Blood Pressure; Child; Etomidate; Female; Fentanyl; Hemodynamics; Humans; Male; Methohexital; Middle Aged; Muscle Rigidity; Nitrous Oxide; Preanesthetic Medication; Thiopental

1985
[Modification of cardiac circulation and respiratory parameters by alfentanil].
    Der Anaesthesist, 1984, Volume: 33, Issue:5

    Topics: Adult; Alfentanil; Analgesics, Opioid; Atropine; Female; Fentanyl; Hemodynamics; Humans; Injections, Intravenous; Male; Respiration; Time Factors

1984
The effect of preanaesthetic oral trazodone hydrochloride on the induction dose of propofol: a preliminary retrospective study.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:5

    Topics: Alfentanil; Anesthetics, Intravenous; Animals; Atropine; Dogs; Humans; Propofol; Retrospective Studies; Trazodone

2022