Page last updated: 2024-09-05

atropine and ajmaline

atropine has been researched along with ajmaline in 27 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(ajmaline)
Trials
(ajmaline)
Recent Studies (post-2010) (ajmaline)
26,7111,2591,69794243123
26,7111,2591,697904

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)ajmaline (IC50)
Cytochrome P450 2D6Homo sapiens (human)1
Sodium channel protein type 1 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 4 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 7 subunit alphaHomo sapiens (human)8.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.04
Sodium channel protein type 5 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 9 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 2 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 3 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 11 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 8 subunit alphaHomo sapiens (human)8.2
Sodium channel protein type 10 subunit alphaHomo sapiens (human)8.2

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199020 (74.07)18.7374
1990's3 (11.11)18.2507
2000's1 (3.70)29.6817
2010's3 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duck, HJ; Fleischmann, JH; Neugebauer, A; Schauer, J; Trenckmann, H1
Chazov, EI1
Csapo, G1
Bär, FW; Farré, J; Ross, D; Vanagt, EJ; Wellens, HJ; Wiener, I1
Arlotti, M; Brera, V; Finzi, A; Lotto, A1
Barnay, C; Medvedowsky, JL1
Alday, LE; Amuchástegui, LM; Moreyra, E1
Chiche, P; Denizeau, JP; Lellouch, A1
Gil, R; Kaźmierczak, J; Kornacewicz-Jach, Z; Zinka, E1
Gil, R1
Pidrman, V; Pleskot, M; Tilser, P1
Diedrich, R; Hardewig, A1
Hasegawa, T; Narusawa, T; Saito, O; Suzuki, Y; Uchijima, H1
Bender, F1
Di Matteo, J; Guize, L; Heulin, A; Le Pailleur, C; Meilhac, B; Vacheron, A2
Neuss, H; Schlepper, M1
Narula, OS1
Cherrier, F; Faivre, G; Perrot, B1
Barousse, AP; Ferreiro, F; Vita, NA1
Bettini, R; Dal Forno, P; Disertori, M; Furlanello, F; Inama, G; Stefenelli, C; Vergara, G; Zuechi, S1
Bressan, M; Buja, GF; Dalla Volta, S; Marinato, PG; Melacini, P; Nava, A1
Eichler, HG; Gouya, G; Schmetterer, L; Wolzt, M; Zanaschka, G1
Trappe, HJ1
Bänsch, D; Gromann, A; Noack, T; Patejdl, R1
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1

Reviews

3 review(s) available for atropine and ajmaline

ArticleYear
[Treatment of arrhythmia at coronary care units].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Volume: 32, Issue:9

    Topics: Adult; Aged; Ajmaline; Animals; Arrhythmias, Cardiac; Atropine; Bretylium Compounds; Cardiac Complexes, Premature; Coronary Care Units; Dogs; Electrocardiography; Female; Heart Block; Humans; Isoproterenol; Lidocaine; Male; Myocardial Infarction; Pacemaker, Artificial; Phenytoin; Procainamide; Quinidine; Tachycardia; Ventricular Fibrillation

1974
Wolff-Parkinson-White Syndrome. A review.
    Circulation, 1973, Volume: 47, Issue:4

    Topics: Adult; Ajmaline; Atropine; Cardiac Catheterization; Digitalis Glycosides; Electric Stimulation; Electrocardiography; Heart; Heart Atria; Heart Conduction System; Humans; Male; Methods; Pacemaker, Artificial; Procainamide; Propranolol; Quinidine; Tachycardia; Vagus Nerve; Wolff-Parkinson-White Syndrome

1973
[Progress in arrhythmology].
    Giornale italiano di cardiologia, 1981, Volume: 11 Suppl 1

    Topics: Adolescent; Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiac Pacing, Artificial; Child; Electrocardiography; Exercise Test; Heart Conduction System; Humans; Middle Aged; Propafenone; Propiophenones; Sick Sinus Syndrome; Stimulation, Chemical; Verapamil; Wolff-Parkinson-White Syndrome

1981

Trials

1 trial(s) available for atropine and ajmaline

ArticleYear
Is the ECG measure RSh a promising technique for detecting class I antiarrhythmic drug action in men?
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Adenosine; Adult; Ajmaline; Anti-Arrhythmia Agents; Atropine; Disopyramide; Electrocardiography; Humans; Injections, Intravenous; Isoproterenol; Male; Norepinephrine; Propranolol; Reproducibility of Results; Sodium Channel Blockers; Verapamil

1995

Other Studies

23 other study(ies) available for atropine and ajmaline

ArticleYear
[Drug therapy of myocardial infarct in ambulatory practice].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1975, Apr-15, Volume: 30, Issue:8

    Topics: Acidosis; Adrenergic beta-Antagonists; Aftercare; Ajmaline; Ambulatory Care; Anticoagulants; Arrhythmias, Cardiac; Atropine; Cardiac Complexes, Premature; Cardiac Glycosides; Glucocorticoids; Heart Block; Heart Failure; Hospitalization; Humans; Lidocaine; Meperidine; Metaproterenol; Morphine; Myocardial Infarction; Nitroglycerin; Tachycardia

1975
[Treatment of rhythm and conduction disorders].
    Kardiologiia, 1975, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Ajmaline; Arrhythmias, Cardiac; Atropine; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Inosine; Isoproterenol; Quinidine

1975
Paroxysmal nonreentrant tachycardias due to simultaneous conduction in dual atrioventricular nodal pathways.
    The American journal of cardiology, 1979, Volume: 43, Issue:5

    Topics: Adult; Ajmaline; Atrial Fibrillation; Atrioventricular Node; Atropine; Bundle of His; Cardiac Pacing, Artificial; Electrocardiography; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Metoprolol; Models, Biological; Tachycardia, Paroxysmal; Verapamil

1979
Reciprocal tachycardias using accessory pathways with long conduction times.
    The American journal of cardiology, 1979, Volume: 44, Issue:6

    Topics: Adult; Ajmaline; Atropine; Bundle-Branch Block; Cardiac Pacing, Artificial; Child; Electrocardiography; Female; Heart Conduction System; Humans; Male; Physical Exertion; Tachycardia; Tachycardia, Paroxysmal; Time Factors; Wolff-Parkinson-White Syndrome

1979
[Second degree A-V block with "minimal increment" wenckebach phenomenon, simulating a mobitz type II block. Electrophysiological and pharmacological study (author's transl)].
    Giornale italiano di cardiologia, 1979, Volume: 9, Issue:11

    Topics: Aged; Ajmaline; Atropine; Bundle of His; Bundle-Branch Block; Cardiac Pacing, Artificial; Diagnosis, Differential; Electric Stimulation; Electrocardiography; Female; Heart Block; Humans; Male; Middle Aged

1979
[Significance of pharmacodynamics tests in the study of sinus node function].
    Archives des maladies du coeur et des vaisseaux, 1976, Volume: 69, Issue:1

    Topics: Ajmaline; Atropine; Benzofurans; Electric Stimulation; Glucagon; Heart Block; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Pharmacology

1976
Mobitz II AV block within the His bundle, with progression to complete heart block.
    British heart journal, 1976, Volume: 38, Issue:8

    Topics: Ajmaline; Atropine; Bundle of His; Electrocardiography; Female; Heart Block; Heart Conduction System; Humans; Middle Aged; Time Factors

1976
Autonomic influences and cardiac conduction in patients with sinus node disease.
    Cardiology, 1976, Volume: 61 suppl 1

    Topics: Adult; Aged; Ajmaline; Arrhythmia, Sinus; Atropine; Blood Pressure; Bradycardia; Bundle of His; Digitalis Glycosides; Female; Heart Arrest; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Neostigmine; Pacemaker, Artificial; Sinoatrial Block

1976
[Mitral valve prolapse. Atrial stimulation, ajmaline test and "pharmacological denervation" in the evaluation of ventricular repolarization].
    Kardiologia polska, 1992, Volume: 37, Issue:8

    Topics: Adolescent; Adult; Ajmaline; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart; Heart Atria; Heart Ventricles; Humans; Male; Middle Aged; Mitral Valve Prolapse; Propranolol

1992
[Evaluation of the activity of the heart conduction system with special reference to the sinoatrial node automatism in patients with mitral valve prolapse syndrome].
    Annales Academiae Medicae Stetinensis, 1991, Volume: 37

    Topics: Action Potentials; Adolescent; Adult; Ajmaline; Arrhythmia, Sinus; Atrial Function, Right; Atropine; Female; Heart Conduction System; Humans; Male; Middle Aged; Mitral Valve Prolapse; Propranolol; Sinoatrial Node; Tachycardia, Supraventricular; Ventricular Function, Right

1991
[Combinations of anti-arrhythmia agents and the heart conduction system].
    Vnitrni lekarstvi, 1988, Volume: 34, Issue:1

    Topics: Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atropine; Drug Therapy, Combination; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Male; Metaproterenol; Middle Aged

1988
[What is assured in the treatment of heart arrhythmia?].
    Der Internist, 1972, Volume: 13, Issue:12

    Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Cardiac Complexes, Premature; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil

1972
[Modern therapy of cardiac arrhythmias].
    Schweizerische medizinische Wochenschrift, 1973, Feb-24, Volume: 103, Issue:8

    Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil

1973
[Importance of auricular stimulation and pharmacodynamic tests in the diagnosis of syncopes with a normal electrocardiogram].
    Archives des maladies du coeur et des vaisseaux, 1974, Volume: 67, Issue:7

    Topics: Adolescent; Adult; Aged; Ajmaline; Atropine; Bundle of His; Electrocardiography; Female; Heart Atria; Heart Block; Humans; Male; Methods; Middle Aged; Pacemaker, Artificial; Stimulation, Chemical; Syncope

1974
[Value of recording the bundle of His potential with pharmacodynamic tests in heart conduction disorders].
    Annales de medecine interne, 1974, Volume: 125, Issue:4

    Topics: Action Potentials; Adolescent; Adult; Aged; Ajmaline; Atrioventricular Node; Atropine; Bundle of His; Bundle-Branch Block; Electrocardiography; Female; Heart Block; Heart Conduction System; Humans; Male; Middle Aged; Procainamide; Sinoatrial Node

1974
Changes of refractory periods in the A-V conduction system induced by antiarrhythmic drugs. A study using His bundle recordings.
    Acta cardiologica, 1974, Volume: Suppl 18

    Topics: Adult; Ajmaline; Aniline Compounds; Anti-Arrhythmia Agents; Atrial Function; Atropine; Bundle of His; Bundle-Branch Block; Diethylamines; Electrocardiography; Female; Heart Atria; Heart Conduction System; Heart Rate; Humans; Indans; Male; Middle Aged; Neural Conduction; Refractory Period, Electrophysiological; Sparteine

1974
[Values of the effective anterograde refractory period of the bundle of His].
    Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74, Issue:4

    Topics: Ajmaline; Atropine; Bundle of His; Electric Stimulation; Electrocardiography; Electrophysiology; Heart Atria; Heart Block; Heart Conduction System; Humans

1981
[Incomplete right bundle-branch block in chronic Chagas' disease patients].
    Medicina, 1983, Volume: 43, Issue:1

    Topics: Ajmaline; Atropine; Blood Pressure; Bundle-Branch Block; Carotid Sinus; Chagas Cardiomyopathy; Electrocardiography; Exercise Test; Female; Humans; Male; Massage

1983
A pharmacological approach to the study of AV conduction in man.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Aged; Ajmaline; Atrioventricular Node; Atropine; Female; Heart Conduction System; Humans; Male; Middle Aged; Neural Conduction; Refractory Period, Electrophysiological; Verapamil

1980
[Life-threatening brady- and tachyarrhythmias].
    Der Internist, 2010, Volume: 51, Issue:8

    Topics: Adenosine; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atropine; Bradycardia; Defibrillators, Implantable; Electric Countershock; Electrocardiography; Emergencies; Epinephrine; Heart Rate; Humans; Pacemaker, Artificial; Signal Processing, Computer-Assisted; Tachycardia

2010
Effects of ajmaline on contraction patterns of isolated rat gastric antrum and portal vein smooth muscle strips and on neurogenic relaxations of gastric fundus.
    Pflugers Archiv : European journal of physiology, 2019, Volume: 471, Issue:7

    Topics: Ajmaline; Animals; Atropine; Electric Stimulation; Female; Gastric Fundus; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Portal Vein; Pyloric Antrum; Rats; Rats, Wistar; Synaptic Transmission; Tetrodotoxin

2019
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010