Compounds > atropine
Page last updated: 2024-09-05

atropine and acetylcysteine

atropine has been researched along with acetylcysteine in 14 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(acetylcysteine)		Trials
(acetylcysteine)		Recent Studies (post-2010) (acetylcysteine)
26,7111,2591,69714,5801,0465,960

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's2 (14.29)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ostler, HB1
Archer, SL; Chesler, E; Kulik, TJ; Weir, EK1
Bergman, NA; Waltemath, CL1
Alphin, RS; Callaham, EM; Foxwell, MH; Smith, WL; Yanni, JM1
Bowden, CA; Krenzelok, EP1
Hahn, LJ; Jeng, JH; Kuo, MY; Kuo, YS; Tsai, CL; Yang, PJ1
Bast, A; den Hartog, GJ; Haenen, GR; van der Vijgh, WJ; Vegt, E1
Birdane, YO; Buyukokuroglu, ME; Cemek, M; Yavuz, Y; Yurumez, Y1
El-Ebiary, AA; Elsharkawy, RE; Hashem, AA; Soliman, MA; Soliman, NA1

Reviews

2 review(s) available for atropine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical applications of commonly used contemporary antidotes. A US perspective.
    Drug safety, 1997, Volume: 16, Issue:1

    Topics: Acetylcysteine; Antidotes; Antivenins; Atropine; Deferoxamine; Flumazenil; Humans; Hydroxocobalamin; Naloxone; Physostigmine; Poisoning; Succimer

1997

Trials

1 trial(s) available for atropine and acetylcysteine

ArticleYear
N-acetylcysteine in Acute Organophosphorus Pesticide Poisoning: A Randomized, Clinical Trial.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:2

    Topics: Acetylcysteine; Adolescent; Adult; Atropine; Dose-Response Relationship, Drug; Egypt; Female; Glutathione; Hospitalization; Humans; Length of Stay; Male; Malondialdehyde; Middle Aged; Organophosphate Poisoning; Oxidative Stress; Pesticides; Respiration, Artificial; Treatment Outcome; Young Adult

2016

Other Studies

11 other study(ies) available for atropine and acetylcysteine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Corneal perforation in nontuberculous (staphylococcal) phlyctenular keratoconjunctivitis.
    American journal of ophthalmology, 1975, Volume: 79, Issue:3

    Topics: Acetylcysteine; Adolescent; Adrenal Cortex Hormones; Atropine; Blepharitis; Contact Lenses; Corneal Ulcer; Culture Techniques; Humans; Keratoconjunctivitis; Male; Ophthalmic Solutions; Sodium; Staphylococcal Infections; Sulfacetamide; Time Factors

1975
The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 183, Issue:1

    Topics: Acetylcysteine; Animals; Aorta; Atropine; Blood Pressure; Dinoprost; Dogs; Hypoxia; Lung; Meclofenamic Acid; Methylene Blue; Prostaglandins F; Pulmonary Artery; Substance P; Vascular Resistance; Vasoconstriction

1986
Increased respiratory resistance provoked by endotracheal administration of aerosols.
    The American review of respiratory disease, 1973, Volume: 108, Issue:3

    Topics: Acetylcysteine; Adult; Aerosols; Aged; Airway Resistance; Atropine; Bronchi; Humans; Intubation, Intratracheal; Lung Compliance; Middle Aged; Water

1973
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response.
    International archives of allergy and applied immunology, 1984, Volume: 74, Issue:4

    Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Expectorants; Hypersensitivity, Immediate; Immune Sera; Methods; Methysergide; Mucus; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains; Trachea

1984
Arecoline cytotoxicity on human oral mucosal fibroblasts related to cellular thiol and esterase activities.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:7

    Topics: Acetylcysteine; Antimetabolites; Areca; Arecoline; Atropine; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Esterases; Expectorants; Fibroblasts; Ganglionic Stimulants; Humans; Maleates; Mouth Mucosa; Muscarinic Antagonists; Plants, Medicinal; Sulfhydryl Compounds; Thiolester Hydrolases

1999
Hypochlorous acid is a potent inhibitor of acetylcholinesterase.
    Toxicology and applied pharmacology, 2002, Jun-15, Volume: 181, Issue:3

    Topics: Acetylcholinesterase; Acetylcysteine; Animals; Atropine; Cholinergic Fibers; Cholinesterase Inhibitors; Electric Stimulation; Expectorants; Guinea Pigs; Hypochlorous Acid; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; Muscle Tonus; Muscle, Smooth; Trachea

2002
Beneficial effect of N-acetylcysteine against organophosphate toxicity in mice.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Acetylcysteine; Animals; Atropine; Cholinesterase Inhibitors; Drug Therapy, Combination; Fenthion; Free Radical Scavengers; Glutathione; Injections, Intraperitoneal; Injections, Subcutaneous; Insecticides; Kaplan-Meier Estimate; Male; Malondialdehyde; Mice; Nitrates; Nitrites; Oxidative Stress; Time Factors

2007