atropine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 21 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 3,530 | 7 | 389 |
| Protein | Taxonomy | atropine (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 13 (61.90) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP | 1 |
| Kung, HF; Kung, MP; Zhuang, ZP | 1 |
| Feniuk, W; Humphrey, PP; Perren, MJ | 1 |
| Osborne, NN | 1 |
| Akaike, A; Hirose, A; Sasa, M; Takaori, S | 1 |
| Dreteler, GH; Saxena, PR; Wouters, W | 1 |
| Jordan, D; Ramage, AG; Shepheard, SL | 1 |
| Arvidsson, LE; Gradin, K; Hedner, T; Hjorth, S; Persson, B; Pettersson, A | 1 |
| Fozard, JR; Ramage, AG | 1 |
| Cortés, R; Palacios, JM; Pazos, A | 1 |
| Jednak, MA; Judge, K; Ram, JL | 1 |
| Buchheit, KH; Buhl, T | 1 |
| Hong, E; Meneses, A | 1 |
| Cassel, JC; Jackisch, R; Jeltsch, H; Lauth, D; Neufang, B; Szabo, B | 1 |
| Ahlénius, S; Björkstrand, E; Smedh, U; Uvnäs-Moberg, K | 1 |
| Alper, RH; Bowman, M; Braun, CJ; Szabó, A | 1 |
| Henley, WN; Vladic, F | 1 |
| Cocks, TM; Moffatt, JD; Page, CP | 1 |
| Astier, B; Blier, P; Chouvet, G; Debonnel, G; Faure, C; Haddjeri, N; Lucas, G; Mnie-Filali, O; Renaud, B | 1 |
| Barthelmebs, M; García, M; Luisa Martín, M; Morán, A; San Román, L | 1 |
| Bland, BH; Crooks, R; Jackson, J | 1 |
21 other study(ies) available for atropine and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetral in (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Iodine Radioisotopes; Ligands; Rats; Receptors, Serotonin; Stereoisomerism; Tetrahydronaphthalenes; Tritium | 1993 |
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Ganglionic Blockers; In Vitro Techniques; Indoles; Ketanserin; Methiothepin; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Serotonin; Saphenous Vein; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents | 1991 |
Effects of GTP, forskolin, sodium fluoride, serotonin, dopamine, and carbachol on adenylate cyclase in Teleost retina.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Atropine; Carbachol; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fishes; GTP-Binding Proteins; Guanosine Triphosphate; Pertussis Toxin; Retina; Serotonin; Sodium Fluoride; Tetrahydronaphthalenes; Virulence Factors, Bordetella | 1990 |
Inhibition of hippocampal CA1 neurons by 5-hydroxytryptamine, derived from the dorsal raphe nucleus and the 5-hydroxytryptamine1A agonist SM-3997.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Atropine; Hippocampus; Iontophoresis; Isoindoles; Male; Neurons; Parasympathetic Nervous System; Piperazines; Pyramidal Tracts; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1990 |
Comparison of the cardiovascular effects of the 5-HT1A receptor agonist flesinoxan with that of 8-OH-DPAT in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Decerebrate State; Heart Rate; Hemodynamics; Imidazoles; In Vitro Techniques; Male; Naphthalenes; Ondansetron; Piperazines; Piperidines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
Actions of 8-OH-DPAT on sympathetic and respiratory drives, blood pressure and heart rate in the rabbit.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Anesthesia; Animals; Atropine; Blood Pressure; Heart; Heart Rate; Kidney; Male; Pentobarbital; Phrenic Nerve; Rabbits; Respiration; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes; Urethane | 1990 |
Cardiovascular effects in the Sprague-Dawley rat of 8-hydroxy-2(di-N-propylamino) tetralin, a selective 5-hydroxytryptamine receptor agonist.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Blood Pressure; Heart Rate; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Male; Methiothepin; Naphthalenes; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Time Factors | 1985 |
Evidence that the putative 5-HT1A receptor agonists, 8-OH-DPAT and ipsapirone, have a central hypotensive action that differs from that of clonidine in anaesthetised cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Cats; Clonidine; Dioxanes; Heart Rate; Idazoxan; Male; Naphthalenes; Neurons; Pyrimidines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Trimethaphan; Vagotomy | 1987 |
Quantitative receptor autoradiography: application to the characterization of multiple receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Autoradiography; Benzodiazepinones; Binding, Competitive; Brain; Carbachol; Hippocampus; Indoles; Oxotremorine; Pindolol; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Serotonin; Superior Colliculi; Tetrahydronaphthalenes | 1984 |
Antagonists of cholinergic and serotonergic responses of Aplysia buccal muscle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Aplysia; Atropine; Cholinergic Antagonists; Hexamethonium; In Vitro Techniques; Mecamylamine; Muscle Contraction; Muscle, Smooth; Piperazines; Pirenzepine; Serotonin Antagonists | 1994 |
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ligands; Male; Metoclopramide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; para-Aminobenzoates; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Tetrodotoxin; Tropanes; Tropisetron | 1994 |
Mechanism of action of 8-OH-DPAT on learning and memory.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Association Learning; Atropine; Conditioning, Operant; Dextroamphetamine; Fenclonine; Food; Learning; Male; Memory; Rats; Rats, Wistar | 1994 |
Downregulation of muscarinic- and 5-HT1B-mediated modulation of [3H]acetylcholine release in hippocampal slices of rats with fimbria-fornix lesions and intrahippocampal grafts of septal origin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Brain Tissue Transplantation; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Cholinesterase Inhibitors; Diffusion Chambers, Culture; Down-Regulation; Electric Stimulation; Female; Hippocampus; Hydroxyindoleacetic Acid; Mecamylamine; Methiothepin; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Norepinephrine; Oxotremorine; Physostigmine; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Serotonin; Septal Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 1995 |
The oxytocin receptor antagonist 1-deamino-2-D-Tyr-(OEt)-4-Thr-8-Orn-oxytocin inhibits effects of the 5-HT1A receptor agonist 8-OH-DPAT on plasma levels of insulin, cholecystokinin and somatostatin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Cholecystokinin; Gastrins; Immune Sera; Insulin; Iodine Radioisotopes; Male; Oxytocin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Serotonin Receptor Agonists; Somatostatin; Vasotocin | 1996 |
Cardiovascular effects produced by R-(+)-8-hydroxy-2-(di-n-propylamino) tetralin in the preoptic area of conscious rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Hemodynamics; Male; Methiothepin; Microinjections; Parasympatholytics; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 1996 |
Hypothyroid-induced changes in autonomic control have a central serotonergic component.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Atropine; Autonomic Nervous System; Blood Pressure; Body Temperature; Brain; Cardiovascular System; Heart Rate; Hypothyroidism; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Receptor Agonists | 1997 |
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Boron Compounds; Botulinum Toxins, Type A; Calcium Channel Blockers; Calcium Channels; Cartilage; Electric Stimulation; Epithelial Cells; Epithelium; Female; Ganglia, Parasympathetic; Inositol 1,4,5-Trisphosphate Receptors; Ketanserin; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; omega-Conotoxin GVIA; Receptors, Cytoplasmic and Nuclear; Serotonin; Surface-Active Agents; Tetrodotoxin; Trachea | 2004 |
In-vivo modulation of central 5-hydroxytryptamine (5-HT1A) receptor-mediated responses by the cholinergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Body Temperature; Male; Motor Activity; Muscarinic Antagonists; Neurons; Parasympathetic Nervous System; Paroxetine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Swimming | 2004 |
The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Blood Pressure; Diabetes Mellitus, Experimental; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Spinal Cord; Tryptamines; Vasoconstriction | 2006 |
Dissociable pathways facilitate theta and non-theta states in the median raphe--septohippocampal circuit.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adjuvants, Anesthesia; Anesthetics, Local; Animals; Atropine; Brain Waves; Fourier Analysis; Functional Laterality; Hippocampus; Male; Neural Pathways; Procaine; Raphe Nuclei; Rats; Rats, Long-Evans; Serotonin Receptor Agonists | 2012 |