Page last updated: 2024-09-05

atropine and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

atropine has been researched along with 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one in 6 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
Trials
(7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
Recent Studies (post-2010) (7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
26,7111,2591,697217016

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one (IC50)
Substance-P receptorHomo sapiens (human)0.03
Substance-P receptorCavia porcellus (domestic guinea pig)0.032

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Joos, GF; Kips, JC; Pauwels, RA1
Damas, J1
Freire-Maia, L; Leite, R; Matos, IM; Teixeira, MM1
Couture, R; Lessard, A1
De Man, JG; De Schepper, HU; De Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC1
Dickson, EJ; Hennig, GW; Heredia, DJ; McCann, CJ; Smith, TK1

Other Studies

6 other study(ies) available for atropine and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

ArticleYear
In vivo characterization of the tachykinin receptors involved in the direct and indirect bronchoconstrictor effect of tachykinins in two inbred rat strains.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:5

    Topics: Airway Resistance; Animals; Atropine; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Captopril; Dose-Response Relationship, Drug; Indoles; Isoindoles; Male; Methysergide; Neurokinin A; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Serotonin; Substance P; Thiorphan

1994
Thermolytic salivation, substance P and kinins in rats.
    Archives of physiology and biochemistry, 1995, Volume: 103, Issue:4

    Topics: Albumins; Animals; Atropine; Body Temperature Regulation; Body Weight; Hot Temperature; Indoles; Isoindoles; Kininogens; Kinins; Male; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Reference Values; Salivation; Substance P

1995
Pharmacological evidence that neuropeptides mediate part of the actions of scorpion venom on the guinea pig ileum.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Animals; Atropine; Biphenyl Compounds; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Isoindoles; Muscarinic Antagonists; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Neuropeptides; Scorpion Venoms; Stereoisomerism; Substance P

1999
Modulation of cardiac activity by tachykinins in the rat substantia nigra.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Benzamides; Blood Pressure; Hemodynamics; Indoles; Isoindoles; Male; Microinjections; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; Oligopeptides; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P; Substantia Nigra; Tachycardia; Tachykinins

2001
Functional characterisation of tachykinin receptors in the circular muscle layer of the mouse ileum.
    Regulatory peptides, 2005, Sep-15, Volume: 130, Issue:3

    Topics: Action Potentials; Analgesics; Animals; Antipsychotic Agents; Atropine; Electric Stimulation; Ileum; Indoles; Isoindoles; Mice; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurons; Nitroarginine; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P

2005
The mechanisms underlying the generation of the colonic migrating motor complex in both wild-type and nNOS knockout mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:2

    Topics: Action Potentials; Analgesics; Animals; Atropine; Colon; Enzyme Inhibitors; Intestinal Mucosa; Isoindoles; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscarinic Antagonists; Muscle, Smooth; Myoelectric Complex, Migrating; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroarginine

2010