Page last updated: 2024-09-05

atropine and 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione

atropine has been researched along with 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione in 6 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione)
Trials
(2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione)
Recent Studies (post-2010) (2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione)
26,7111,2591,69770221

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baker, R; Book, T; Freedman, SB; Herbert, RH; Kneen, CO; MacLeod, AM; Merchant, KJ; Saunders, J; Showell, GA; Street, LJ1
Baker, R; Cassidy, M; Freedman, SB; Harley, EA; Iversen, LL; Kneen, C; MacLeod, AM; Merchant, KJ; Saunders, J; Snow, RJ1
Baker, R; Freedman, SB; Harley, EA; Saunders, J; Showell, GA; Snow, RJ1
Cheung, CL; De Boer, T; Tonnaer, JA1
Ortegón, ME; Raffa, RB; Watson, M1
Ferree, AW; Isacson, O; Seo, H1

Other Studies

6 other study(ies) available for atropine and 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione

ArticleYear
Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:10

    Topics: Animals; Cerebral Cortex; In Vitro Techniques; Ligands; Oxadiazoles; Parasympathomimetics; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

1990
Novel quinuclidine-based ligands for the muscarinic cholinergic receptor.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:4

    Topics: Animals; Binding Sites; Cerebral Cortex; Computer Simulation; Kinetics; Models, Chemical; Oxadiazoles; Quinuclidines; Rats; Receptors, Muscarinic; Structure-Activity Relationship

1990
2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Dioxolanes; Dioxoles; In Vitro Techniques; Inositol Phosphates; Male; Molecular Conformation; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Spiro Compounds; Structure-Activity Relationship

1988
cGMP formation and phosphoinositide turnover in rat brain slices are mediated by pharmacologically distinct muscarinic acetylcholine receptors.
    European journal of pharmacology, 1991, Jul-12, Volume: 207, Issue:3

    Topics: Animals; Atropine; Brain; Carbachol; Cyclic GMP; Guanylate Cyclase; Hippocampus; Inositol Phosphates; Male; Nitroprusside; Phosphatidylinositols; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Succinimides

1991
Reciprocal hindlimb scratching and putative subtype-selective muscarinic agents.
    European journal of pharmacology, 1988, Dec-13, Volume: 158, Issue:3

    Topics: Animals; Atropine; Binding Sites; Diamines; Dose-Response Relationship, Drug; Drug Antagonism; Hindlimb; Injections, Spinal; Male; Mice; Parasympathomimetics; Pilocarpine; Receptors, Muscarinic; Succinimides; Trihexyphenidyl

1988
Cortico-hippocampal APP and NGF levels are dynamically altered by cholinergic muscarinic antagonist or M1 agonist treatment in normal mice.
    The European journal of neuroscience, 2002, Volume: 15, Issue:3

    Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Atropine; Cerebral Cortex; Cholinergic Fibers; Down-Regulation; Drug Interactions; Female; Hippocampus; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Nerve Growth Factor; Parasympathomimetics; Receptor, Muscarinic M1; Receptors, Muscarinic; Succinimides; Synaptic Transmission

2002