Compounds > atropine
Page last updated: 2024-09-05

atropine and 2-chloroadenosine

atropine has been researched along with 2-chloroadenosine in 6 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(2-chloroadenosine)		Trials
(2-chloroadenosine)		Recent Studies (post-2010) (2-chloroadenosine)
26,7111,2591,6978891347

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)2-chloroadenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.5377
Adenosine receptor A1Rattus norvegicus (Norway rat)0.037
Adenosine receptor A2bRattus norvegicus (Norway rat)0.16
Adenosine receptor A2aRattus norvegicus (Norway rat)0.16

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ballati, L; Manzini, S1
Gustafsson, LE1
Carneiro, FS; Giachini, FR; Inscho, EW; Leite, R; Tostes, RC; Webb, RC1

Reviews

1 review(s) available for atropine and 2-chloroadenosine

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993

Other Studies

5 other study(ies) available for atropine and 2-chloroadenosine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea-pigs.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anesthesia; Animals; Atropine; Bronchi; Capsaicin; Drug Resistance; Guinea Pigs; Inosine; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Serotonin; Vagus Nerve

1990
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
    Acta physiologica Scandinavica, 1984, Volume: 122, Issue:2

    Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Rolipram; Synaptic Transmission; Tetrodotoxin; Theophylline

1984
Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Tosylate; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Penile Erection; Phenylephrine; Prazosin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles

2007