Page last updated: 2024-09-05

atropine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

atropine has been researched along with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine in 16 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(1-(5-isoquinolinesulfonyl)-2-methylpiperazine)
Trials
(1-(5-isoquinolinesulfonyl)-2-methylpiperazine)
Recent Studies (post-2010) (1-(5-isoquinolinesulfonyl)-2-methylpiperazine)
26,7111,2591,6973,41241631

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's10 (62.50)18.2507
2000's2 (12.50)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Obara, K; Usuki, T; Yabu, H1
Francis, J; Pon, DJ; Qu, Y; Sen, AK; Torchia, J1
Yau, WM1
Dandona, P; Jeremy, JY1
Dehaye, JP; Turner, RJ; Valdez, IH1
Garg, LC; Mohuczy-Dominiak, D; Saha, PK1
Artemenko, IP; Hokin, LE; Los, GV1
Almazan, G; Larocca, JN1
Eguchi, T; Ishida, H; Ishikawa, Y; Skowronski, MT1
Chakder, S; Rattan, S1
Alroy, G; Su, H; Yaari, Y1
Büyükafsar, K; Levent, A1
Jin, L; Priviero, FB; Teixeira, CE; Webb, RC; Ying, Z1
Allain, AV; Kadowitz, PJ; Lasker, GF; Murthy, SN; Pankey, EA; Stasch, JP1
Beil, M; Danhof, M; Fu, F; Luttringer, O; Ploeger, BA; Rigel, DF; Snelder, N; Stanski, DR1

Other Studies

16 other study(ies) available for atropine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Calcium and potassium channel regulation by protein phosphorylation in smooth muscle cells of guinea pig taenia coli.
    Advances in experimental medicine and biology, 1992, Volume: 311

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Atropine; Calcium Channels; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Isoquinolines; Marine Toxins; Membrane Potentials; Models, Biological; Muscle, Smooth; Nifedipine; Oxazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Piperazines; Potassium Channels; Protein Kinase C

1992
Carbachol-stimulated phosphorylation of a 170-kDa endogenous protein in avian salt gland cells.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Atropine; Carbachol; Ducks; Ionomycin; Isoquinolines; Kinetics; Molecular Weight; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Proteins; Salt Gland; Staurosporine; Tetradecanoylphorbol Acetate

1991
Mode of stimulation of gallbladder contraction by substance K.
    The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Female; Gallbladder; Guinea Pigs; Isoquinolines; Kinetics; Muscle Contraction; Muscle, Smooth; Neurokinin A; Piperazines; Tetrodotoxin

1990
Fluoride but not phorbol esters stimulate rat urinary bladder prostanoid synthesis: investigations into the roles of G proteins and protein kinase C.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 29, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atropine; Bucladesine; Calcimycin; Carbachol; Fluorides; GTP-Binding Proteins; Isoquinolines; Nifedipine; Phorbol Esters; Piperazines; Prostaglandins; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Urinary Bladder; Verapamil

1987
Beta-adrenergic stimulation and cAMP mobilize Ca2+ from an IP3-insensitive pool in rat submandibular granular ducts.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Alkaloids; Animals; Atenolol; Atropine; Calcium; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Isoquinolines; Kinetics; Male; Phentolamine; Piperazines; Propanolamines; Propranolol; Protein Kinase C; Protein Kinase Inhibitors; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Staurosporine; Submandibular Gland

1993
Cholinergic inhibition of Na-K-ATPase via activation of protein kinase C in Madin-Darby canine kidney cells.
    Journal of the American Society of Nephrology : JASN, 1993, Volume: 4, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Atropine; Carbachol; Cells, Cultured; Dogs; Enzyme Activation; Epithelium; Inositol Phosphates; Isoquinolines; Kidney; Naphthalenes; Parasympathomimetics; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Staurosporine; Sulfonamides

1993
Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers.
    Advances in enzyme regulation, 1996, Volume: 36

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzyme Inhibitors; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Maleimides; Neuroblastoma; Nickel; Phosphatidylinositols; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Tumor Cells, Cultured

1996
Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors.
    Journal of neuroscience research, 1997, Dec-01, Volume: 50, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Atropine; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Cholinergic Agents; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate

1997
Acetylcholine acts on M3 muscarinic receptors and induces the translocation of aquaporin5 water channel via cytosolic Ca2+ elevation in rat parotid glands.
    Biochemical and biophysical research communications, 1998, Apr-28, Volume: 245, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Aquaporin 5; Aquaporins; Atropine; Calcimycin; Calcium; Calcium Channel Blockers; Cytosol; Diamines; Enzyme Inhibitors; Gallic Acid; Ion Channels; Ionophores; Male; Membrane Proteins; Parasympatholytics; Parotid Gland; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Staurosporine

1998
Mechanisms and sites of action of endothelins 1 and 2 on the opossum internal anal sphincter smooth muscle tone in vitro.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic Agents; Anal Canal; Animals; Atropine; Calcium Channel Blockers; Calmodulin; Cyclooxygenase Inhibitors; Endothelin-1; Endothelin-2; Enzyme Inhibitors; Guanethidine; In Vitro Techniques; Indomethacin; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; omega-Conotoxin GVIA; Opossums; Peptides; Polymethacrylic Acids; Protein Kinase C; Substance P; Sulfonamides; Tachyphylaxis; Tetrodotoxin

1999
Protein kinase C mediates muscarinic block of intrinsic bursting in rat hippocampal neurons.
    The Journal of physiology, 1999, Jul-01, Volume: 518, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Atropine; Carbachol; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyramidal Cells; Rats; Receptors, Muscarinic; Signal Transduction; Tetraethylammonium; Tetrodotoxin

1999
Expression of Rho-kinase (ROCK-1 and ROCK-2) and its substantial role in the contractile activity of the sheep ureter.
    British journal of pharmacology, 2004, Volume: 143, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Aorta; Atropine; Blotting, Western; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Guanethidine; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Sheep; Tetrodotoxin; Ureter; Vasoconstrictor Agents; Vasodilator Agents

2004
Comparative pharmacological analysis of Rho-kinase inhibitors and identification of molecular components of Ca2+ sensitization in the rat lower urinary tract.
    Biochemical pharmacology, 2007, Aug-15, Volume: 74, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Animals; Atropine; Blotting, Western; Calcium Signaling; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Enzyme Inhibitors; Guanine Nucleotide Dissociation Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Urethra; Urinary Bladder

2007
The selective Rho-kinase inhibitor azaindole-1 has long-lasting erectile activity in the rat.
    Urology, 2013, Volume: 81, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Area Under Curve; Atropine; Blood Pressure; Diamines; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Male; Muscarinic Antagonists; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Peripheral Nerve Injuries; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; rho-Associated Kinases; Signal Transduction; Time Factors

2013
Drug effects on the CVS in conscious rats: separating cardiac output into heart rate and stroke volume using PKPD modelling.
    British journal of pharmacology, 2014, Volume: 171, Issue:22

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Amlodipine; Animals; Atropine; Enalapril; Hemodynamics; Hydrochlorothiazide; Hypertension; Male; Models, Biological; Prazosin; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY

2014