Page last updated: 2024-09-04

atrasentan and zoledronic acid

atrasentan has been researched along with zoledronic acid in 2 studies

Compound Research Comparison

Studies
(atrasentan)
Trials
(atrasentan)
Recent Studies (post-2010)
(atrasentan)
Studies
(zoledronic acid)
Trials
(zoledronic acid)
Recent Studies (post-2010) (zoledronic acid)
358411084,1086202,610

Protein Interaction Comparison

ProteinTaxonomyatrasentan (IC50)zoledronic acid (IC50)
Carbonic anhydrase 12Homo sapiens (human)0.316
Geranylgeranyl pyrophosphate synthaseHomo sapiens (human)0.318
Carbonic anhydrase 2Homo sapiens (human)0.062
72 kDa type IV collagenaseHomo sapiens (human)7
Farnesyl pyrophosphate synthaseHomo sapiens (human)0.2144
Farnesyl diphosphate synthaseEscherichia coli K-121.1
Farnesyl pyrophosphate synthase Leishmania donovani0.11
Geranylgeranyl pyrophosphate synthaseSaccharomyces cerevisiae S288C0.424
Carbonic anhydrase 9Homo sapiens (human)5.323
Carbonic anhydrase 14Homo sapiens (human)0.092

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carducci, MA; Walczak, JR1
Kantoff, P; Kaufman, DS; Michaelson, MD; Oh, WK; Smith, MR1

Reviews

1 review(s) available for atrasentan and zoledronic acid

ArticleYear
Pharmacological treatments for prostate cancer.
    Expert opinion on investigational drugs, 2002, Volume: 11, Issue:12

    Topics: Antibodies, Monoclonal; Atrasentan; Dendritic Cells; Diphosphonates; Genetic Therapy; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Male; Microtubules; Prostatic Neoplasms; Pyrrolidines; Radiopharmaceuticals; Zoledronic Acid

2002

Trials

1 trial(s) available for atrasentan and zoledronic acid

ArticleYear
Randomized phase II study of atrasentan alone or in combination with zoledronic acid in men with metastatic prostate cancer.
    Cancer, 2006, Aug-01, Volume: 107, Issue:3

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Atrasentan; Biomarkers, Tumor; Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Disease Progression; Dyspnea; Edema; Humans; Imidazoles; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Pyrrolidines; Treatment Outcome; Zoledronic Acid

2006