atrasentan has been researched along with rifampin in 2 studies
| Studies (atrasentan) | Trials (atrasentan) | Recent Studies (post-2010) (atrasentan) | Studies (rifampin) | Trials (rifampin) | Recent Studies (post-2010) (rifampin) |
|---|---|---|---|---|---|
| 358 | 41 | 108 | 20,468 | 1,499 | 6,552 |
| Protein | Taxonomy | atrasentan (IC50) | rifampin (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 2.949 | |
| Caspase-1 | Homo sapiens (human) | 8.319 | |
| Alpha-synuclein | Homo sapiens (human) | 7.1 | |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | 0.03 | |
| DNA-directed RNA polymerase subunit beta | Mycobacterium tuberculosis H37Rv | 0.01 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.5 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Achari, R; Carr, RA; Doan, TT; Jankowski, JR; Katz, DA; Locke, CS; Sleep, DJ; Wang, P; Xiong, H | 1 |
| Gordi, T | 1 |
1 trial(s) available for atrasentan and rifampin
| Article | Year |
|---|---|
Dual effects of rifampin on the pharmacokinetics of atrasentan.
Topics: Adult; Area Under Curve; Atrasentan; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Synergism; Endothelin A Receptor Antagonists; Enzyme Induction; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pyrrolidines; Rifampin | 2007 |
1 other study(ies) available for atrasentan and rifampin
| Article | Year |
|---|---|
Comments on "Dual effects of rifampin on the pharmacokinetics of atrasentan".
Topics: Area Under Curve; Atrasentan; Drug Interactions; Half-Life; Humans; Protein Binding; Pyrrolidines; Rifampin; Tissue Distribution | 2007 |