atrasentan has been researched along with nitroarginine in 4 studies
| Studies (atrasentan) | Trials (atrasentan) | Recent Studies (post-2010) (atrasentan) | Studies (nitroarginine) | Trials (nitroarginine) | Recent Studies (post-2010) (nitroarginine) |
|---|---|---|---|---|---|
| 358 | 41 | 108 | 3,935 | 11 | 175 |
| Protein | Taxonomy | atrasentan (IC50) | nitroarginine (IC50) |
|---|---|---|---|
| Nitric oxide synthase, endothelial | Bos taurus (cattle) | 1.2 | |
| Nitric oxide synthase, endothelial | Homo sapiens (human) | 0.38 | |
| Nitric oxide synthase, brain | Homo sapiens (human) | 1.265 | |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | 4.12 | |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | 0.5 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 6.2 | |
| Nitric oxide synthase, brain | Mus musculus (house mouse) | 0.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braam, B; Gröne, HJ; Joles, JA; Koomans, HA; Opgenorth, TJ; Rabelink, TJ; Verhagen, AM | 1 |
| Gariepy, CE; Tykocki, NR; Watts, SW | 1 |
| Hamel, E; Ongali, B; Papadopoulos, P | 1 |
| Kimura, K; Koyama, M; Matsumura, Y; Ohkita, M | 1 |
4 other study(ies) available for atrasentan and nitroarginine
| Article | Year |
|---|---|
Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitric oxide synthase inhibition.
Topics: Animals; Atrasentan; Blood Pressure; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; Kidney; Male; Nitric Oxide Synthase; Nitroarginine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Time Factors | 1998 |
Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Atrasentan; Dinoprost; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Nitroarginine; Oligopeptides; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Endothelin A; Receptor, Endothelin B; Tunica Intima; Tunica Media; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Venae Cavae; Viper Venoms | 2009 |
Selective in vivo antagonism of endothelin receptors in transforming growth factor-beta1 transgenic mice that mimic the vascular pathology of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Atrasentan; Blood Vessels; Brain; Cerebral Arteries; Cerebrovascular Circulation; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Female; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitroarginine; Pyrrolidines; Transforming Growth Factor beta1; Vasoconstriction; Vasodilation; Vasodilator Agents; Vibrissae | 2010 |
Reduced NO production rapidly aggravates renal function through the NF-κB/ET-1/ETA receptor pathway in DOCA-salt-induced hypertensive rats.
Topics: Animals; Atrasentan; Desoxycorticosterone; Disease Models, Animal; Disease Susceptibility; Endothelin-1; Hypertension; Kidney Diseases; Male; NF-kappa B; Nitric Oxide; Nitroarginine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Severity of Illness Index; Sodium Chloride, Dietary; Thiocarbamates | 2012 |