atrasentan has been researched along with ng-nitroarginine methyl ester in 8 studies
Studies (atrasentan) | Trials (atrasentan) | Recent Studies (post-2010) (atrasentan) | Studies (ng-nitroarginine methyl ester) | Trials (ng-nitroarginine methyl ester) | Recent Studies (post-2010) (ng-nitroarginine methyl ester) |
---|---|---|---|---|---|
358 | 41 | 108 | 12,640 | 117 | 2,342 |
Protein | Taxonomy | atrasentan (IC50) | ng-nitroarginine methyl ester (IC50) |
---|---|---|---|
Neutrophil elastase | Homo sapiens (human) | 2.7 | |
Nitric oxide synthase, endothelial | Homo sapiens (human) | 2.1 | |
Nitric oxide synthase, brain | Homo sapiens (human) | 1.1167 | |
Nitric oxide synthase, inducible | Mus musculus (house mouse) | 2.6 | |
Nitric oxide synthase, inducible | Homo sapiens (human) | 8 | |
Collagenase 3 | Homo sapiens (human) | 2.7 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (25.00) | 18.2507 |
2000's | 3 (37.50) | 29.6817 |
2010's | 2 (25.00) | 24.3611 |
2020's | 1 (12.50) | 2.80 |
Authors | Studies |
---|---|
Opgenorth, TJ; Polakowski, JS; Pollock, DM; Wegner, CD | 1 |
Opgenorth, TJ; Polakowski, JS; Pollock, DM; Pollock, JS | 1 |
Banes, AK; Chen, AF; Fink, GD; Galligan, JJ; Li, L; Watts, SW | 1 |
Abassi, Z; Bishara, B; Hoffman, A; Karram, T; Khatib, S; Winaver, J | 1 |
Agharazii, M; Bélanger, S; Larivière, R; Lebel, M; Lemieux, P; Therrien, F | 1 |
Bkaily, G; Brochu, I; D'Orléans-Juste, P; Desbiens, L; Gobeil, F; Houde, M; Semaan, W; Simard, E | 1 |
Dobešová, Z; Kuneš, J; Vaněčková, I; Vernerová, Z; Zicha, J | 1 |
Abdelhady, SA; Darwish, IE; El-Deeb, NM; El-Mas, MM; Gowayed, MA; Habib, YH | 1 |
8 other study(ies) available for atrasentan and ng-nitroarginine methyl ester
Article | Year |
---|---|
Beneficial effect of ETA receptor blockade in a rat model of radiocontrast-induced nephropathy.
Topics: Acute Kidney Injury; Animals; Atrasentan; Contrast Media; Creatinine; Diatrizoate; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Antagonists; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1997 |
Role of endothelin ET(A) receptors in the hypertension produced by 4-day L-nitroarginine methyl ester and cyclosporine treatment.
Topics: Animals; Atrasentan; Cyclosporine; Drinking Behavior; Endothelin Receptor Antagonists; Enzyme Inhibitors; Feeding Behavior; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin | 1998 |
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension.
Topics: Acetophenones; Allopurinol; Animals; Atrasentan; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Venae Cavae; Viper Venoms; Xanthine Oxidase | 2003 |
Adverse effects of pneumoperitoneum on renal function: involvement of the endothelin and nitric oxide systems.
Topics: Animals; Atrasentan; Blood Pressure; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroglycerin; Pneumoperitoneum, Artificial; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation; Renal Plasma Flow; Vasodilator Agents | 2008 |
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency | 2009 |
High salt-induced hypertension in B2 knockout mice is corrected by the ETA antagonist, A127722.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Atrasentan; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Peptides, Cyclic; Pyrrolidines; Receptor, Bradykinin B2; Sodium; Sodium Chloride, Dietary; Telemetry | 2013 |
Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet.
Topics: Animal Feed; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Calcium; Calcium Channels, L-Type; Captopril; Endothelin A Receptor Antagonists; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Pentolinium Tartrate; Pyrrolidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 2015 |
Modulation by antenatal therapies of cardiovascular and renal programming in male and female offspring of preeclamptic rats.
Topics: Animals; Atrasentan; Cardiovascular Diseases; Disease Models, Animal; Endothelin A Receptor Antagonists; Female; Kidney Diseases; Male; Methyldopa; Naphthalenes; NG-Nitroarginine Methyl Ester; Pre-Eclampsia; Pregnancy; Prenatal Care; Propionates; Rats; Receptors, Thromboxane A2, Prostaglandin H2; Sex Factors; Sympatholytics | 2021 |