Page last updated: 2024-09-04

atrasentan and hydralazine

atrasentan has been researched along with hydralazine in 2 studies

Compound Research Comparison

Studies (atrasentan)	Trials (atrasentan)	Recent Studies (post-2010) (atrasentan)	Studies (hydralazine)	Trials (hydralazine)	Recent Studies (post-2010) (hydralazine)
358	41	108	4,580	364	393

Protein Interaction Comparison

Protein	Taxonomy	hydralazine (IC50)
Myeloperoxidase	Homo sapiens (human)	1.265
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	3.649
Lactoperoxidase	Bos taurus (cattle)	1.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, NC; Chen, CC; Lee, TM; Lin, MS	1
Agharazii, M; Bélanger, S; Larivière, R; Lebel, M; Lemieux, P; Therrien, F	1

Other Studies

2 other study(ies) available for atrasentan and hydralazine

Article	Year
Effect of endothelin receptor antagonists on ventricular susceptibility in postinfarcted rats. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atrasentan; Blotting, Western; Bosentan; Cardiac Pacing, Artificial; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; GAP-43 Protein; Hemodynamics; Hydralazine; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Myocardial Infarction; Myocardium; Nerve Growth Factor; Neurofilament Proteins; Norepinephrine; Polymerase Chain Reaction; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Sympathetic Nervous System; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation	2008
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat. European journal of pharmacology, 2009, Apr-01, Volume: 607, Issue:1-3 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency	2009

Article

Year

Effect of endothelin receptor antagonists on ventricular susceptibility in postinfarcted rats.

American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atrasentan; Blotting, Western; Bosentan; Cardiac Pacing, Artificial; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; GAP-43 Protein; Hemodynamics; Hydralazine; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Myocardial Infarction; Myocardium; Nerve Growth Factor; Neurofilament Proteins; Norepinephrine; Polymerase Chain Reaction; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Sympathetic Nervous System; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation

2008

Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.

European journal of pharmacology, 2009, Apr-01, Volume: 607, Issue:1-3

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency

2009