Page last updated: 2024-09-04

atrasentan and dinoprost

atrasentan has been researched along with dinoprost in 3 studies

Compound Research Comparison

Studies
(atrasentan)
Trials
(atrasentan)
Recent Studies (post-2010)
(atrasentan)
Studies
(dinoprost)
Trials
(dinoprost)
Recent Studies (post-2010) (dinoprost)
3584110811,5549401,936

Protein Interaction Comparison

ProteinTaxonomyatrasentan (IC50)dinoprost (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.0025
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.0713
Prostaglandin G/H synthase 1Homo sapiens (human)0.14
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.3
Prostaglandin G/H synthase 2Homo sapiens (human)0.14
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)4.2
Prostaglandin F2-alpha receptorBos taurus (cattle)0.14
Prostaglandin F2-alpha receptorHomo sapiens (human)0.0139
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.216
Prostaglandin D2 receptorHomo sapiens (human)4.5
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.287

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dabbs Loomis, E; Elmarakby, AA; Pollock, DM; Pollock, JS1
Gariepy, CE; Tykocki, NR; Watts, SW1
Chen, CC; Hsu, YJ; Lee, TM1

Other Studies

3 other study(ies) available for atrasentan and dinoprost

ArticleYear
ETA receptor blockade attenuates hypertension and decreases reactive oxygen species in ETB receptor-deficient rats.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Atrasentan; Blood Pressure; Dinoprost; Disease Models, Animal; Down-Regulation; Endothelin A Receptor Antagonists; Endothelins; Hypertension; Male; Pyrrolidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Sodium Chloride, Dietary; Superoxides; Time Factors

2004
Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Atrasentan; Dinoprost; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Nitroarginine; Oligopeptides; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Endothelin A; Receptor, Endothelin B; Tunica Intima; Tunica Media; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Venae Cavae; Viper Venoms

2009
Impact of elevated uric acid on ventricular remodeling in infarcted rats with experimental hyperuricemia.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Allopurinol; Analysis of Variance; Animals; Antioxidants; Atrasentan; Biomarkers; Cyclic N-Oxides; Dinoprost; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Fibrosis; Gout Suppressants; Hypertrophy, Left Ventricular; Hyperuricemia; Isoprostanes; Male; Myocardial Infarction; Myocardium; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Spin Labels; Superoxides; Time Factors; Up-Regulation; Uric Acid; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling; Xanthine Oxidase

2011