atrasentan has been researched along with captopril in 4 studies
| Studies (atrasentan) | Trials (atrasentan) | Recent Studies (post-2010) (atrasentan) | Studies (captopril) | Trials (captopril) | Recent Studies (post-2010) (captopril) |
|---|---|---|---|---|---|
| 358 | 41 | 108 | 10,320 | 1,514 | 890 |
| Protein | Taxonomy | atrasentan (IC50) | captopril (IC50) |
|---|---|---|---|
| Leukotriene A-4 hydrolase | Homo sapiens (human) | 3.6 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.084 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.0173 | |
| Succinyl-diaminopimelate desuccinylase | Haemophilus influenzae Rd KW20 | 3.3 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.1004 | |
| Beta-lactamase | Pseudomonas aeruginosa | 5 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.011 | |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | 3.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burke, SE; Dayton, BD; Gagne, GD; Lubbers, NL; Opgenorth, TJ; Wegner, CD; Wessale, JL | 1 |
| Davis, G; Hammad, FT; Wheatley, AM | 1 |
| Dobešová, Z; Kuneš, J; Vaněčková, I; Vernerová, Z; Zicha, J | 1 |
| El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R | 1 |
4 other study(ies) available for atrasentan and captopril
| Article | Year |
|---|---|
Selective antagonism of the ET(A) receptor reduces neointimal hyperplasia after balloon-induced vascular injury in pigs.
Topics: Angioplasty, Balloon; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Blood Pressure; Captopril; Carotid Artery Injuries; Carotid Artery, Common; Collagen; Endothelin Receptor Antagonists; Endothelin-1; Hyperplasia; Iliac Artery; Male; Muscle, Smooth, Vascular; Pyrrolidines; Receptor, Endothelin A; Swine; Swine, Miniature; Tunica Intima | 1997 |
Role of endothelin ET(A) receptor antagonism in the post-transplant renal response to angiotensin II in the rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Blood Pressure; Captopril; Cold Temperature; Endothelin Receptor Antagonists; Glomerular Filtration Rate; Ischemia; Kidney Transplantation; Male; Pyrrolidines; Rats; Rats, Inbred Lew; Receptor, Endothelin A; Renal Circulation; Renin-Angiotensin System; Sodium | 2001 |
Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet.
Topics: Animal Feed; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Calcium; Calcium Channels, L-Type; Captopril; Endothelin A Receptor Antagonists; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Pentolinium Tartrate; Pyrrolidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 2015 |
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 2016 |