atrasentan has been researched along with avosentan in 5 studies
| Studies (atrasentan) | Trials (atrasentan) | Recent Studies (post-2010) (atrasentan) | Studies (avosentan) | Trials (avosentan) | Recent Studies (post-2010) (avosentan) |
|---|---|---|---|---|---|
| 358 | 41 | 108 | 29 | 10 | 15 |
| Protein | Taxonomy | atrasentan (IC50) | avosentan (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Homo sapiens (human) | 0.9 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.0023 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ritz, E; Wenzel, RR | 1 |
| Kohan, DE; Rabelink, TJ | 1 |
| Angelini, ML; Baraldi, O; Cianciolo, G; Iorio, M; Stefoni, S | 1 |
| Cheng, G; Li, B; Li, Y; Liu, D; Lu, S; Xiao, J; Yuan, W; Zhao, Z | 1 |
| Chi, J; Dong, B; Huang, Y; Lv, W; Wang, YG; Zhou, Y | 1 |
4 review(s) available for atrasentan and avosentan
| Article | Year |
|---|---|
Endothelin receptor blockade in patients with diabetic nephropathy.
Topics: Atrasentan; Clinical Trials as Topic; Creatinine; Diabetic Nephropathies; Endothelin Receptor Antagonists; Glomerular Filtration Rate; Humans; Pyridines; Pyrimidines; Pyrrolidines; Serum Albumin | 2011 |
Emerging drugs for chronic kidney disease.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Glycosaminoglycans; Humans; Pyridines; Pyridoxamine; Pyrimidines; Pyrrolidines; Renal Insufficiency, Chronic | 2014 |
Endothelin-receptor antagonist can reduce blood pressure in patients with hypertension: a meta-analysis.
Topics: Antihypertensive Agents; Atrasentan; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Bosentan; Endothelin Receptor Antagonists; Humans; Hypertension; Middle Aged; Models, Statistical; Phenylpropionates; Pyridines; Pyrimidines; Pyrrolidines; Randomized Controlled Trials as Topic; Sulfonamides; Survival Analysis; Tetrazoles | 2017 |
Efficacy and safety of endothelin receptor antagonists in type 2 diabetic kidney disease: A systematic review and meta-analysis of randomized controlled trials.
Topics: Albuminuria; Atrasentan; Bosentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelin Receptor Antagonists; Heart Failure; Humans; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic | 2021 |
1 other study(ies) available for atrasentan and avosentan
| Article | Year |
|---|---|
Endothelin antagonist as add-on treatment for proteinuria in diabetic nephropathy: is there light at the end of the tunnel?
Topics: Albuminuria; Atrasentan; Diabetic Nephropathies; Endothelins; Glomerular Filtration Rate; Humans; Proteinuria; Pyridines; Pyrimidines; Pyrrolidines; Renin-Angiotensin System; Treatment Outcome | 2011 |