atrasentan has been researched along with angiotensin ii in 16 studies
| Studies (atrasentan) | Trials (atrasentan) | Recent Studies (post-2010) (atrasentan) | Studies (angiotensin ii) | Trials (angiotensin ii) | Recent Studies (post-2010) (angiotensin ii) |
|---|---|---|---|---|---|
| 358 | 41 | 108 | 38,152 | 1,089 | 7,413 |
| Protein | Taxonomy | atrasentan (IC50) | angiotensin ii (IC50) |
|---|---|---|---|
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.002 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.002 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0018 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.0055 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.004 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 11 (68.75) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chiou, WJ; Dickinson, R; Opgenorth, TJ; Wu-Wong, JR | 1 |
| Burke, SE; Cox, BF; Ford, TT; Fu, KI; Lubbers, NL; Nelson, RA; Padley, RJ; Wegner, CD | 1 |
| Alexander, BT; Cockrell, KL; Granger, JP; Herrington, JN; Rinewalt, AN | 1 |
| Derebail, VK; Pollock, DM; Pollock, JS; Yamamoto, T | 1 |
| Ballew, JR; Fink, GD | 1 |
| Davis, G; Hammad, FT; Wheatley, AM | 1 |
| Boemke, W; Francis, RC; Höhne, C; Kaczmarczyk, G | 2 |
| Boemke, W; Donaubauer, B; Francis, RC; Höhne, C; Kaisers, U; Klein, A | 1 |
| Banes-Berceli, AK; Ketsawatsomkron, P; Marrero, MB; Ogbi, S; Patel, B; Pollock, DM | 1 |
| Boemke, W; Francis, RC; Höhne, C; Kaisers, U; Klein, A; Pickerodt, P | 1 |
| Agharazii, M; Bélanger, S; Larivière, R; Lebel, M; Lemieux, P; Therrien, F | 1 |
| Boesen, EI; Pollock, DM; Pollock, JS | 1 |
| Alexander, BT; Intapad, S; Ojeda, NB; Royals, TP; Varney, E | 1 |
| El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R | 1 |
| Červenka, L; Gawrys, O; Jíchová, Š; Kala, P; Kompanowska-Jezierska, E; Maxová, H; Miklovič, M; Sadowski, J; Škaroupková, P; Táborský, M; Vaněčková, I; Vaňourková, Z; Veselka, J; Walkowska, A | 1 |
16 other study(ies) available for atrasentan and angiotensin ii
| Article | Year |
|---|---|
Endothelin attenuates apoptosis in human smooth muscle cells.
Topics: Angiotensin II; Annexin A5; Apoptosis; Atrasentan; Cell Survival; DNA Fragmentation; Endothelin Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Male; Muscle, Smooth; Paclitaxel; Pericardium; Phosphatidylserines; Propidium; Prostate; Pyrrolidines | 1997 |
Evidence for vasoconstriction mediated by the endothelin-B receptor in domestic swine.
Topics: Angiotensin II; Animals; Animals, Domestic; Atrasentan; Blood Pressure; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Femoral Artery; Protein Precursors; Pyrrolidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Swine; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2000 |
Enhanced renal expression of preproendothelin mRNA during chronic angiotensin II hypertension.
Topics: Angiotensin II; Animals; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Gene Expression Regulation; Glomerular Filtration Rate; Hemodynamics; Hypertension; Infusions, Intravenous; Kidney; Kidney Cortex; Kidney Medulla; Male; Protein Precursors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Renal Circulation; RNA, Messenger; Transcription, Genetic; Urodynamics | 2001 |
Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Role of ET(A) receptors in experimental ANG II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Heart Rate; Hypertension; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium Chloride, Dietary; Vasoconstrictor Agents; Water-Electrolyte Balance | 2001 |
Role of endothelin ET(A) receptor antagonism in the post-transplant renal response to angiotensin II in the rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Blood Pressure; Captopril; Cold Temperature; Endothelin Receptor Antagonists; Glomerular Filtration Rate; Ischemia; Kidney Transplantation; Male; Pyrrolidines; Rats; Rats, Inbred Lew; Receptor, Endothelin A; Renal Circulation; Renin-Angiotensin System; Sodium | 2001 |
Haemodynamic and hormonal changes during haemorrhage in conscious dogs treated with an endothelin-A receptor antagonist.
Topics: Action Potentials; Acute Disease; Angiotensin II; Animals; Atrasentan; Blood Pressure; Cardiac Output; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Hemorrhage; Norepinephrine; Pyrrolidines; Random Allocation; Receptor, Endothelin A; Vascular Resistance; Vasodilator Agents; Vasopressins | 2002 |
Effect of angiotensin II and endothelin-1 receptor blockade on the haemodynamic and hormonal changes after acute blood loss and after retransfusion in conscious dogs.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Blood Transfusion; Cardiac Output; Dogs; Endothelin-1; Epinephrine; Female; Glomerular Filtration Rate; Hemodynamics; Hemorrhage; Losartan; Norepinephrine; Pyrrolidines; Receptor, Endothelin A; Stroke Volume; Urine; Vascular Resistance; Vasopressins | 2004 |
Endothelin-a receptor blockade does not debilitate the cardiovascular and hormonal adaptation to xenon or isoflurane anesthesia in dogs.
Topics: Acclimatization; Anesthetics, Inhalation; Angiotensin II; Animals; Atrasentan; Cardiovascular Physiological Phenomena; Dogs; Endothelin A Receptor Antagonists; Epinephrine; Female; Isoflurane; Norepinephrine; Pyrrolidines; Vasopressins; Xenon | 2006 |
Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrrolidines; Rats; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Tetrazoles; Time Factors; Tyrphostins; Vasodilation | 2007 |
ETA-receptor blockade impairs vasoconstriction after hemorrhage in xenon-anesthetized dogs treated with an AT1-receptor antagonist.
Topics: Anesthesia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrasentan; Blood Pressure; Dogs; Endothelin A Receptor Antagonists; Endothelin-1; Female; Hemodynamics; Hemorrhage; Losartan; Pyrrolidines; Vascular Resistance; Vasoconstriction; Vasopressins; Xenon | 2008 |
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency | 2009 |
Contrasting effects of intervention with ETA and ETB receptor antagonists in hypertension induced by angiotensin II and high-salt diet.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Hypertension; Male; Nitrates; Nitrites; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Treatment Outcome | 2010 |
Sex-Specific Effect of Endothelin in the Blood Pressure Response to Acute Angiotensin II in Growth-Restricted Rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Blood Pressure; Blotting, Western; Enalapril; Endothelin Receptor Antagonists; Endothelin-1; Female; Fetal Growth Retardation; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Ovariectomy; Pregnancy; Pyrrolidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; Sex Factors | 2015 |
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 2016 |
Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Endothelin-1; Endothelins; Fistula; Heart Failure; Hypertension; Rats; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptor, Endothelin A | 2023 |