Compounds > atrasentan
Page last updated: 2024-09-04

atrasentan and abt 869

atrasentan has been researched along with abt 869 in 1 studies

Compound Research Comparison

Studies
(atrasentan)		Trials
(atrasentan)		Recent Studies (post-2010)
(atrasentan)		Studies
(abt 869)		Trials
(abt 869)		Recent Studies (post-2010) (abt 869)
35841108841559

Protein Interaction Comparison

ProteinTaxonomyatrasentan (IC50)abt 869 (IC50)
Aurora kinase AHomo sapiens (human)0.76
Cyclin-dependent kinase 1Homo sapiens (human)9.8
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.0321
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)1.9
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0492
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.0313
Fibroblast growth factor receptor 1Homo sapiens (human)5.479
AromataseHomo sapiens (human)0.0418
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.015
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.0364
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.1309
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.0312
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0126
Cyclin-dependent kinase 8Homo sapiens (human)2.158
Angiopoietin-1 receptorHomo sapiens (human)0.0601
Cyclin-dependent kinase 19Homo sapiens (human)0.024

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albert, DH; Banfor, PN; Cox, BF; Davidsen, SK; Franklin, PA; Fryer, RM; Gintant, GA; Segreti, JA; Widomski, DL1

Other Studies

1 other study(ies) available for atrasentan and abt 869

ArticleYear
ETA receptor blockade with atrasentan prevents hypertension with the multitargeted tyrosine kinase inhibitor ABT-869 in telemetry-instrumented rats.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Area Under Curve; Atrasentan; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Endothelin A Receptor Antagonists; Heart Rate; Hypertension; Indazoles; Male; Phenylurea Compounds; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Telemetry

2009